Research Topics
Genomes and Genes | R James WhiteSummaryAffiliation: University of Rochester Country: USA Publications
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Publications
Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human diseaseR James White
Division of Pulmonary and Critical Care Medicine, Center for Cellular and Molecular Cardiology, Aab Institute for Biomedical Sciences, University of Rochester School of Medicine, Rochester, NY 14642, USA
Chest 128:612S-613S. 2005
Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertensionR James White
Division of Pulmonary and Critical Care Medicine, Univ of Rochester, 601 Elmwood Ave, Box 692, Rochester, NY, USA
Am J Physiol Lung Cell Mol Physiol 293:L583-90. 2007..Increased TF expression may contribute to the prothrombotic diathesis and vascular cell proliferation typical of human disease...
Novel therapeutic approaches in pulmonary arterial hypertension: focus on tadalafilY D Levin
Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY, USA
Drugs Today (Barc) 47:145-56. 2011....
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinaseDavid F Meoli
Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, 400 Red Creek Drive, Suite 110, Rochester, NY 14623, USA
Can J Physiol Pharmacol 88:830-9. 2010..This finding may help explain the striking difference in the efficacy of endothelin receptor blockers for pulmonary hypertension as compared to that for systemic cardiovascular disease...
Sildenafil therapy is associated with improved hemodynamics in liver transplantation candidates with pulmonary arterial hypertensionMichael S Gough
Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14623, USA
Liver Transpl 15:30-6. 2009..In conclusion, sildenafil was associated with improved hemodynamics in this small, uncontrolled cohort. A multicenter, prospective evaluation is warranted in this group uniformly excluded from phase III clinical trials...
Thrombin induces fibronectin-specific migration of pulmonary microvascular endothelial cells: requirement of calcium/calmodulin-dependent protein kinase IIDavid F Meoli
Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, New York, USA
Am J Physiol Lung Cell Mol Physiol 297:L706-14. 2009....
Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertensionMatthew Ferrantino
University of Rochester Medical Center, 400 Red Creek Dr, Suite 110, Rochester, NY 14623, USA
Expert Opin Pharmacother 12:2583-93. 2011....
G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular developmentJinjiang Pang
Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Circulation 119:1524-32. 2009..However, there have been no in vivo studies of GIT1 function to date...
Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging miceMin Yee
Department of Pediatrics, School of Medicine and Dentistry, The University of Rochester, Rochester, New York, USA
Am J Pathol 178:2601-10. 2011..People exposed to hyperoxia as neonates may be at increased risk for pulmonary hypertension...
