D J Weiss

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Hemophagocytic syndrome in dogs: 24 cases (1996-2005)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    J Am Vet Med Assoc 230:697-701. 2007
  2. ncbi Evaluation of proliferative disorders in canine bone marrow by use of flow cytometric scatter plots and monoclonal antibodies
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Vet Pathol 38:512-8. 2001
  3. ncbi A retrospective study of the incidence and the classification of bone marrow disorders in the dog at a veterinary teaching hospital (1996-2004)
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 20:955-61. 2006
  4. ncbi New insights into the physiology and treatment of acquired myelodysplastic syndromes and aplastic pancytopenia
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Vet Clin North Am Small Anim Pract 33:1317-34. 2003
  5. ncbi Gene expression and antimicrobial activity of bovine macrophages in response to Mycobacterium avium subsp. paratuberculosis
    D J Weiss
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, MN 55018, USA
    Vet Pathol 41:326-37. 2004
  6. ncbi Sequential patterns of gene expression by bovine monocyte-derived macrophages associated with ingestion of mycobacterial organisms
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    Microb Pathog 37:215-24. 2004
  7. ncbi Comparison of three arginine-glycine-aspartate-containing peptides as inhibitors of equine platelet aggregation
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, USA
    J Vet Pharmacol Ther 27:377-9. 2004
  8. ncbi Recognition and classification of dysmyelopoiesis in the dog: a review
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Vet Intern Med 19:147-54. 2005
  9. ncbi Sideroblastic anemia in 7 dogs (1996-2002)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Vet Intern Med 19:325-8. 2005
  10. ncbi Differentiating benign and malignant causes of lymphocytosis in feline bone marrow
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    J Vet Intern Med 19:855-9. 2005

Collaborators

Detail Information

Publications63

  1. ncbi Hemophagocytic syndrome in dogs: 24 cases (1996-2005)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    J Am Vet Med Assoc 230:697-701. 2007
    ..To determine the frequency, potential causes, and clinical and clinicopathologic features of hemophagocytic syndrome in dogs...
  2. ncbi Evaluation of proliferative disorders in canine bone marrow by use of flow cytometric scatter plots and monoclonal antibodies
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Vet Pathol 38:512-8. 2001
    ..As additional lineage-specific monoclonal antibodies become available, immunophenotyping should become a valuable tool for determination of the lineage of cells in canine myeloproliferative disorders...
  3. ncbi A retrospective study of the incidence and the classification of bone marrow disorders in the dog at a veterinary teaching hospital (1996-2004)
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 20:955-61. 2006
    ..An 8-year retrospective study was conducted to evaluate the prevalence and the classification of canine bone marrow disorders in a clinical pathology service at a university referral hospital...
  4. ncbi New insights into the physiology and treatment of acquired myelodysplastic syndromes and aplastic pancytopenia
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Vet Clin North Am Small Anim Pract 33:1317-34. 2003
    ..Treatment and outcome are dependent on determining the underlying cause of the bone marrow failure...
  5. ncbi Gene expression and antimicrobial activity of bovine macrophages in response to Mycobacterium avium subsp. paratuberculosis
    D J Weiss
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, MN 55018, USA
    Vet Pathol 41:326-37. 2004
    ..Although the intracellular fate of mycobacterial organisms appears to be dependent on a complex interaction between macrophage and organism, phagosome acidification and apoptosis may play central roles in organism survival...
  6. ncbi Sequential patterns of gene expression by bovine monocyte-derived macrophages associated with ingestion of mycobacterial organisms
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    Microb Pathog 37:215-24. 2004
    ..Although multiple genes and metabolic pathways are involved, the capacity of cells to acidify phagosomes and induce apoptosis appears to play a prominent role...
  7. ncbi Comparison of three arginine-glycine-aspartate-containing peptides as inhibitors of equine platelet aggregation
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, USA
    J Vet Pharmacol Ther 27:377-9. 2004
  8. ncbi Recognition and classification of dysmyelopoiesis in the dog: a review
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Vet Intern Med 19:147-54. 2005
    ..Differentiation of the various causes of dysmyelopoiesis is essential for establishing an appropriate therapeutic plan and for determining prognosis...
  9. ncbi Sideroblastic anemia in 7 dogs (1996-2002)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Vet Intern Med 19:325-8. 2005
    ....
  10. ncbi Differentiating benign and malignant causes of lymphocytosis in feline bone marrow
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    J Vet Intern Med 19:855-9. 2005
    ..Cat age, presence of severe anemia, and evidence of inflammatory disease also should be considered...
  11. ncbi Mucosal immune response in cattle with subclinical Johne's disease
    D J Weiss
    Department of Veterinary Biomedical Sciences, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, USA
    Vet Pathol 43:127-35. 2006
    ..avium subsp. paratuberculosis organisms in subclinically infected cows. This effect may be induced, at least in part, by proliferation of regulatory T cells that nonspecifically suppress mucosal immune responsiveness...
  12. ncbi Detection of activated platelets in dogs with primary immune-mediated hemolytic anemia
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 20:682-6. 2006
    ..These data provide support for the hypothesis that platelets circulate in an activated state in many dogs with IMHA...
  13. ncbi Primary myelodysplastic syndromes of dogs: a report of 12 cases
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 14:491-4. 2000
    ..Dogs with primary refractory anemia tend to have prolonged survival and respond to erythropoietin treatment, whereas dogs with primary myelodysplasia have short survival and do not respond to standard treatments...
  14. ncbi Bone marrow pathology in dogs and cats with non-regenerative immune-mediated haemolytic anaemia and pure red cell aplasia
    D J Weiss
    Department of Veterinary and Biomedical Sciences, University of Minnesota, St Paul, MN, USA
    J Comp Pathol 138:46-53. 2008
    ....
  15. ncbi Pure white cell aplasia in a dog
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA
    Vet Clin Pathol 36:373-5. 2007
    ....
  16. ncbi Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium
    Douglas J Weiss
    Department of Veterinary, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, USA
    J Leukoc Biol 83:48-55. 2008
    ..Therefore, signaling through the TLR2 receptor appears to play a role in phagosome trafficking and antimicrobial responses in MAP-infected bovine mononuclear phagocytes...
  17. ncbi Evaluation of antineutrophil IgG antibodies in persistently neutropenic dogs
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Vet Intern Med 21:440-4. 2007
    ..Immune-mediated neutropenia (IMN) is one of several causes of persistent neutropenia in dogs. A test to detect IMN in dogs is not available...
  18. ncbi Review paper: modulation of mononuclear phagocyte function by Mycobacterium avium subsp. paratuberculosis
    D J Weiss
    Department of Veterinary and Biomedical Sciences, University of Minnesota, St Paul, MN 55108, USA
    Vet Pathol 45:829-41. 2008
    ....
  19. ncbi Hematologic alterations in adult cats fed 6 or 12% propylene glycol
    M C Bauer
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    Am J Vet Res 53:69-72. 1992
    ..These data indicate that PG-containing diets cause a dose-dependent erythrocyte destruction, even when fed at concentrations as low as 6%...
  20. ncbi Evaluation of monoclonal antibodies for identification of subpopulations of myeloid cells in bone marrow obtained from dogs
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA
    Am J Vet Res 62:1229-33. 2001
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Four monoclonal antibodies for use in detecting subpopulations of canine bone marrow cells were evaluated. These antibodies should be useful in differentiating the origin of leukemic cells in dogs...
  21. ncbi Hematological alterations in kittens induced by 6 and 12% dietary propylene glycol
    M C Bauer
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    Vet Hum Toxicol 34:127-31. 1992
    ..The increase in reticulocyte count and reduction in RBC lifespan was greater than observed in adult cats. The greater effect in kittens may be due to greater PG intake and not to an inate susceptibility of kitten RBC to PG...
  22. ncbi Expression of interleukin-10 and suppressor of cytokine signaling-3 associated with susceptibility of cattle to infection with Mycobacterium avium subsp paratuberculosis
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 66:1114-20. 2005
    ....
  23. ncbi Use of monoclonal antibodies to refine flow cytometric differential cell counting of canine bone marrow cells
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA
    Am J Vet Res 62:1273-8. 2001
    ..These techniques have potential applications to clinical bone marrow examination and preclinical toxicity studies...
  24. ncbi Effects of propylene glycol-containing diets on acetaminophen-induced methemoglobinemia in cats
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    J Am Vet Med Assoc 196:1816-9. 1990
    ..Methemoglobin concentrations were significantly greater in cats in PG diets after acetaminophen administration. These data indicate that RBC from cats fed PG diets are more susceptible to oxidative stress...
  25. ncbi Effects of nuclear factor-kappaB on regulation of cytokine expression and apoptosis in bovine monocytes exposed to Mycobacterium avium subsp paratuberculosis
    Douglas J Weiss
    Department of Veterinary and Biomedical Science, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 69:804-10. 2008
    ..To evaluate the role of the nuclear factor-kappaB (NF-kappaB) in the response of bovine monocytes to exposure to Mycobacterium avium subsp paratuberculosis (MAP)...
  26. ncbi A critical role of interleukin-10 in the response of bovine macrophages to infection by Mycobacterium avium subsp paratuberculosis
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 66:721-6. 2005
    ..CONCLUSIONS AND CLINICAL RELEVANCE: The capacity of M avium subsp paratuberculosis to induce IL-10 expression may be a major determinant of virulence for this organism...
  27. ncbi Platelet kinetics in dogs treated with a glycoprotein IIb/IIIa peptide antagonist
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Toxicol Pathol 28:310-6. 2000
    ..Platelet counts returned to baseline within 1 week after discontinuation of treatment. These data indicate that RPR 109891 causes rapid and selective sequestration of platelets in the spleen...
  28. ncbi Regulation of expression of major histocompatibility antigens by bovine macrophages infected with Mycobacterium avium subsp. paratuberculosis or Mycobacterium avium subsp. avium
    D J Weiss
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, Minnesota 55108, USA
    Infect Immun 69:1002-8. 2001
    ..avium subsp. paratuberculosis and M. avium subsp. avium for cattle is dependent on a difference in the capacity of the organisms to suppress mycobacterial antigen presentation to T lymphocytes...
  29. ncbi Evaluation of dysmyelopoiesis in cats: 34 cases (1996-2005)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    J Am Vet Med Assoc 228:893-7. 2006
    ..Differentiating between myelodysplastic syndrome with excessive numbers of blast cells and myelodysplastic syndrome with refractory cytopenias was useful in predicting clinical outcome...
  30. ncbi Role of the mitogen-activated protein kinase pathway in the differential response of bovine monocytes to Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium
    Cleverson D Souza
    Department of Veterinary Science, University of Minnesota, St Paul, MN 55108, USA
    Microbes Infect 9:1545-52. 2007
    ..Taken together these data indicate that early transient activation of MAPK-p38 in bovine mononuclear phagocytes by MAP organisms may be a key mechanism involved in the capacity of MAP to survive in bovine monocytes...
  31. ncbi Flow cytometric and immunophenotypic evaluation of acute lymphocytic leukemia in dog bone marrow
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 15:589-94. 2001
    ..Results of this study indicate marked variation in the morphology and immunophenotype of canine lymphocytic leukemia...
  32. ncbi Cell membrane receptors on bovine mononuclear phagocytes involved in phagocytosis of Mycobacterium avium subsp paratuberculosis
    Cleverson D Souza
    Department of Veterinary and Biomedical Science, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 68:975-80. 2007
    ..To determine cell membrane receptors involved in phagocytosis of Mycobacterium avium subsp paratuberculosis (MAP) organisms...
  33. ncbi Role of the MAPK(ERK) pathway in regulation of cytokine expression by Mycobacterium avium subsp paratuberculosis-exposed bovine monocytes
    Cleverson D Souza
    Department of Veterinary and Biomedical Science, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 68:625-30. 2007
    ..To evaluate the role of the mitogen-activated protein kinase extracellular signal-regulated kinase (MAPK(ERK)) pathway in the interaction between Mycobacterium avium subsp paratuberculosis (MAP) organisms and bovine monocytes...
  34. ncbi Evaluation of flow cytometric and automated methods for detection of activated platelets in dogs with inflammatory disease
    Andreas Moritz
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 66:325-9. 2005
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Platelet surface-associated P-selectin and MPC appeared to be useful to detect activated platelets in most dogs with septic and nonseptic inflammatory disease...
  35. ncbi Bone marrow necrosis in dogs: 34 cases (1996-2004)
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    J Am Vet Med Assoc 227:263-7. 2005
    ....
  36. ncbi Differential response of human and bovine platelets to bovine von Willebrand factor and vascular subendothelium
    G H Rao
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA
    Platelets 12:150-5. 2001
    ..In contrast, bovine platelets in blood with low molecular weight heparin as anticoagulant adhered more readily than human cells. These findings suggest that different mechanisms are involved in hemostasis in human and bovine species...
  37. ncbi Determination of differential cell counts in feline bone marrow by use of flow cytometry
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Am J Vet Res 62:474-8. 2001
    ..When combined with fluorescent labeling of lymphocytes, the scatterplot method has potential to provide rapid semiquantitative assessment of bone marrow differential cell counts in cats...
  38. ncbi Mitogen activated protein kinase p38 pathway is an important component of the anti-inflammatory response in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytes
    Cleverson D Souza
    Department of Veterinary and Biomedical Sciences, 1971 Commonwealth Ave, University of Minnesota, St Paul, MN 55108, USA
    Microb Pathog 41:59-66. 2006
    ..Taken together, these results indicated that selective activation of MAPK p38 may be a major mechanism exploited by M. avium subsp. paratuberculosis to circumvent the antimycobacterial effects of mononuclear phagocytes...
  39. ncbi Primary pure red cell aplasia in dogs: 13 cases (1996-2000)
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    J Am Vet Med Assoc 221:93-5. 2002
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Dogs with PRCA appear to respond readily to treatment with immunosuppressive drugs; however, hematologic responses may not be observed for weeks to months after initiation of treatment...
  40. ncbi Liver cytology
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    Vet Clin North Am Small Anim Pract 32:1267-91, vi. 2002
    ....
  41. ncbi Regulation by Jun N-terminal kinase/stress activated protein kinase of cytokine expression in Mycobacterium avium subsp paratuberculosis-infected bovine monocytes
    Cleverson D Souza
    Department of Veterinary and Biomedical Science, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55018, USA
    Am J Vet Res 67:1760-5. 2006
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Activation of JNK/SAPK may be an important mechanism used by Mptb to regulate cytokine expression in bovine monocytes for survival and to alter inflammatory and immune responses...
  42. ncbi A retrospective study of aplastic pancytopenia in the dog: 9 cases (1996-2003)
    Jennifer L Brazzell
    Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA
    Vet Clin Pathol 35:413-7. 2006
    ..Several causes of acquired aplastic pancytopenia are known; however, in some cases, an underlying cause is never determined...
  43. ncbi Aplastic anemia in cats - clinicopathological features and associated disease conditions 1996-2004
    Douglas J Weiss
    Department of Veterinary Biomedical Sciences, University of Minnesota, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA
    J Feline Med Surg 8:203-6. 2006
    ..In some cats, starvation may play a role in the development of marrow aplasia. Some cats with aplastic anemia can have prolonged survival without resolution of the pancytopenia...
  44. ncbi Equine immune-mediated hemolytic anemia associated with Clostridium perfringens infection
    Douglas J Weiss
    Department of Veterinary PathoBiology University of Minnesota, St Paul, MN 55108, USA
    Vet Clin Pathol 32:22-6. 2003
    ..Previous studies have suggested an association between equine immune-mediated hemolytic anemia and clostridial infections or neck abscesses...
  45. ncbi A retrospective study of 19 cases of canine myelofibrosis
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 16:174-8. 2002
    ..Half of the dogs with secondary myelofibrosis recovered from their cytopenias and were alive from 4 months to 5 years after diagnosis...
  46. ncbi Flow cytometric evaluation of canine bone marrow based on intracytoplasmic complexity and CD45 expression
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA
    Vet Clin Pathol 33:96-101. 2004
    ..Several flow cytometric methods have been described, but all have limitations...
  47. ncbi Flow cytometric evaluation of hemophagocytic disorders in canine
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Vet Clin Pathol 31:36-41. 2002
    ..Cytomorphologic evaluation alone may be inadequate to consistently differentiate between benign and malignant forms of hemophagocytic disorders...
  48. ncbi Differential responses of bovine macrophages to Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium
    Douglas J Weiss
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, Minnesota 55108, USA
    Infect Immun 70:5556-61. 2002
    ..Therefore, the combination of inherent resistance to intracellular degradation and suppression of macrophage activation through oversecretion of IL-10 may contribute to the virulence of M. avium subsp. paratuberculosis in cattle...
  49. ncbi Application of flow cytometric techniques to veterinary clinical hematology
    Douglas J Weiss
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, MN 55108, USA
    Vet Clin Pathol 31:72-82. 2002
    ..This report will briefly review the technical aspects of flow cytometry and then focus on techniques with present or potential application to the veterinary clinical laboratory...
  50. ncbi Role of cell membrane receptors in the suppression of monocyte anti-microbial activity against Mycobacterium avium subsp. paratuberculosis
    Cleverson D Souza
    Departments of Veterinary and Biomedical Science, University of Minnesota, St Paul, MN 55108, USA
    Microb Pathog 44:215-23. 2008
    ....
  51. ncbi An indirect flow cytometric test for detection of anti-neutrophil antibodies in dogs
    Douglas J Weiss
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 68:464-7. 2007
    ..To develop a clinically applicable assay for detection of serum anti-neutrophil antibodies in dogs...
  52. ncbi Idiopathic hypereosinophilic syndrome in 3 Rottweilers
    J E Sykes
    Department of Small Animal Clinical Sciences, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 15:162-6. 2001
    ..Despite an extensive search, no underlying cause for the eosinophilia could be identified. In this study, cytogenetic analysis and measurement of serum IgE concentrations were used to differentiate IHES and eosinophilic leukemia...
  53. ncbi Leukocyte response to toxic injury
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    Toxicol Pathol 21:135-40. 1993
    ..Therefore, the time course of onset of leukopenia after drug or chemical exposure and the rapidity of hematopoietic recovery give clues to the mechanism by which granulopoiesis is suppressed...
  54. ncbi Evaluation of lipopolysaccharide-induced activation of equine neutrophils
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Am J Vet Res 63:811-5. 2002
    ..The tests used to detect activated neutrophils in this study may be useful in detecting in vivo neutrophil activation in horses with sepsis and endotoxemia...
  55. ncbi In vitro evaluation of the role of platelet-activating factor and interleukin-8 in Mannheimia haemolytica-induced bovine pulmonary endothelial cell injury
    David J McClenahan
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Am J Vet Res 63:394-401. 2002
    ....
  56. ncbi Evaluation of leukocyte cell surface markers in dogs with septic and nonseptic inflammatory diseases
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Am J Vet Res 65:59-63. 2004
    ..Many dogs with MODS have a compensatory anti-inflammatory response that may compromise their responses to antimicrobials...
  57. ncbi The sepsis-coagulant axis: a review
    D J Weiss
    Department of Veterinary Pathobiology, Colege of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    J Vet Intern Med 12:317-24. 1998
    ..Presently available treatments (i.e., heparin and aspirin) are relatively ineffective in treating DIC; however, newer, more potent drugs may soon be available for clinical use...
  58. ncbi Hematologic response of adult brown mink to oxidative stress
    D J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul
    Vet Hum Toxicol 36:109-11. 1994
    ..However, the high food intake and the mink's position at the top of the food chain may increase its exposure to environmental contaminants...
  59. ncbi Regulation of interleukin-8 expression in porcine alveolar macrophages by bacterial lipopolysaccharide
    G Lin
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    J Biol Chem 269:77-85. 1994
    ..These observations indicate that the expression of IL-8 is an early event in the sequelae to bacterial infection in the lung...
  60. ncbi Evaluation of activated neutrophils in the blood of horses with colic
    Douglas J Weiss
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Am J Vet Res 64:1364-8. 2003
    ..Additional studies are needed to determine whether activated neutrophils contribute directly to the adverse outcome in horses with strangulating colic...
  61. ncbi Canine and feline hematology reference values for the ADVIA 120 hematology system
    Andreas Moritz
    Clinic for Internal Medicine and Forensic Affairs, Faculty of Veterinary Medicine, Justus Liebig University, Giessen, Germany
    Vet Clin Pathol 33:32-8. 2004
    ..The ADVIA 120 is a laser-based hematology analyzer with software applications for animal species. Accurate reference values would be useful for the assessment of new hematologic parameters and for interlaboratory comparisons...
  62. ncbi Effects of short-term racing activity on platelet and neutrophil activation in dogs
    Andreas Moritz
    Clinic for Internal Medicine and Forensic Affairs, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany
    Am J Vet Res 64:855-9. 2003
    ..Additional studies will be needed to determine whether these changes have adverse effects on animal performance or induce tissue injury...
  63. ncbi Flow cytometric detection of activated platelets in the dog
    Andreas Moritz
    Clinic for Internal Medicine and Forensic Affairs, Faculty of Veterinary Medicine, Justus-Liebig University, Giessen, Germany
    Vet Clin Pathol 32:6-12. 2003
    ..The capacity to use EDTA-anticoagulated blood samples and to fix platelets for evaluation at a later time makes the test attractive as a routine diagnostic tool...