Research Topics
| Marc J WeigensbergSummaryAffiliation: University of Southern California Country: USA Publications
Research Grants
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Detail Information
Publications
Association between the metabolic syndrome and serum cortisol in overweight Latino youthMarc J Weigensberg
Department of Pediatrics, University of Southern California, 2250 Alcazar Street, CSC 200, Los Angeles, California 90089 9073, USA
J Clin Endocrinol Metab 93:1372-8. 2008..The purpose of this report is to investigate the associations between metabolic syndrome (MS) and levels of morning serum cortisol in a cohort of overweight Latino youth...
Acute effects of stress-reduction Interactive Guided Imagery(SM) on salivary cortisol in overweight Latino adolescentsMarc J Weigensberg
Department of Pediatrics, Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Altern Complement Med 15:297-303. 2009....
Ethnic differences in insulin action in obese African-American and Latino adolescentsRebecca E Hasson
University of Southern California, Department of Preventive Medicine, 2250 Alcazar Street, Clinical Sciences Center, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 95:4048-51. 2010..It is unclear whether African-Americans demonstrate an exaggerated insulin response to an oral glucose challenge and whether any differences are seen in more obese children in advanced pubertal development...
Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: a longitudinal assessmentMichael I Goran
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Int J Pediatr Obes 1:139-45. 2006..To examine 1-year changes in insulin dynamics in overweight Hispanic children at high-risk of type 2 diabetes as a function of body composition and pubertal transition...
Dietary intake and the metabolic syndrome in overweight Latino childrenEmily E Ventura
Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
J Am Diet Assoc 108:1355-9. 2008..Increases in soluble fiber through the daily consumption of fruits, vegetables, and beans may improve metabolic health in Latino children...
Birth weight and body composition in overweight Latino youth: a longitudinal analysisLouise A Kelly
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 16:2524-8. 2008....
Aerobic and strength training reduces adiposity in overweight Latina adolescentsJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Med Sci Sports Exerc 41:1494-503. 2009....
Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetesMichael I Goran
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 89:207-12. 2004....
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumptionJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Am J Clin Nutr 92:1522-7. 2010..Animal models have also shown that PNPLA3 expression can be regulated by dietary carbohydrate...
Physical activity, sedentary behavior, and the metabolic syndrome in minority youthYa Wen Hsu
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 91803, USA
Med Sci Sports Exerc 43:2307-13. 2011..This study aimed to determine the associations among physical activity, sedentary behavior, and the metabolic syndrome (MetS) in Latino and African American youth using both subjective and objective measures of activity levels...
Randomized control trial to improve adiposity and insulin resistance in overweight Latino adolescentsJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 17:1542-8. 2009..In conclusion, this intense, culturally tailored intervention resulted in no significant intervention effects on measured risk factors with the exception of a beneficial effect on glycemic response to oral glucose...
Longitudinal changes in insulin sensitivity, insulin secretion, and beta-cell function during pubertyGeoff D C Ball
Department of Preventive Medicine, University of Southern California, Los Angeles, USA
J Pediatr 148:16-22. 2006..Future studies are needed to identify whether this difference contributes to the increased risk of type II diabetes in young blacks...
Fasting indicators of insulin sensitivity: effects of ethnicity and pubertal statusTanja C Adam
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes Care 34:994-9. 2011....
Influence of breastfeeding on obesity and type 2 diabetes risk factors in Latino youth with a family history of type 2 diabetesJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes Care 30:784-9. 2007..To determine whether breastfeeding is related to total adiposity, regional adiposity, and glucose and insulin dynamics in overweight Latino youth throughout puberty...
The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivityMartha L Cruz
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
J Clin Endocrinol Metab 89:108-13. 2004..Improving insulin resistance may be crucial for the prevention of chronic disease in this at-risk population...
Decreased beta-cell function in overweight Latino children with impaired fasting glucoseMarc J Weigensberg
Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Diabetes Care 28:2519-24. 2005..The actual risk of progression of IFG to type 2 diabetes remains to be determined by prospective longitudinal studies...
Insulin sensitivity as an independent predictor of fat mass gain in Hispanic adolescentsTanja C Adam
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes Care 32:2114-5. 2009..The purpose of this study was to examine the relationship between changes in insulin sensitivity and subsequent changes in fat mass in obese Hispanic children over 3 consecutive years...
The relation of sugar intake to beta cell function in overweight Latino childrenJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Am J Clin Nutr 82:1004-10. 2005..These results emphasize the need for early nutritional interventions to reduce daily sugar intake in overweight Latino children and potentially reduce their risk for type 2 diabetes...
Ethnic differences in pancreatic fat accumulation and its relationship with other fat depots and inflammatory markersKim Anne Le
Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
Diabetes Care 34:485-90. 2011..Our aim was to assess ethnic and sex differences in PFF and its relationship to other fat depots, circulating free fatty acids (FFA), insulin secretion and sensitivity, and inflammation in obese adolescents and young adults...
Cortisol is negatively associated with insulin sensitivity in overweight Latino youthTanja C Adam
University of Southern California, Department of Preventive Medicine, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 95:4729-35. 2010..The purpose of the present study was to investigate the cross-sectional and longitudinal associations of serum morning cortisol and aspects of insulin action in Latino children and adolescents (8-13 yr) at risk for type 2 diabetes...
Association of breakfast skipping with visceral fat and insulin indices in overweight Latino youthKatharine E Alexander
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 17:1528-33. 2009..Eating breakfast is associated with lower visceral adiposity in overweight Latino youth. Interventions focused on increasing breakfast consumption are warranted...
Parental history and risk of type 2 diabetes in overweight Latino adolescents: a longitudinal analysisLouise A Kelly
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes Care 30:2700-5. 2007....
Associations of dietary sugar and glycemic index with adiposity and insulin dynamics in overweight Latino youthJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Am J Clin Nutr 86:1331-8. 2007..Few studies have examined the relation between dietary carbohydrate quality, adiposity, and insulin dynamics in children...
Persistence of the metabolic syndrome over 3 annual visits in overweight Hispanic children: association with progressive risk for type 2 diabetesEmily E Ventura
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
J Pediatr 155:535-41. 2009..To examine an association between persistent metabolic syndrome (MetS) and the risk for type 2 diabetes in overweight Hispanic children...
Insulin sensitivity, cardiorespiratory fitness, and physical activity in overweight Hispanic youthGeoff D C Ball
Department of Preventive Medicine, Los Angeles County University of Southern California Medical Center, University of Southern California, Los Angeles, California 90089, USA
Obes Res 12:77-85. 2004..To determine whether cardiorespiratory fitness and/or physical activity (PA) were related to measures of insulin sensitivity and secretion independent of body composition in overweight Hispanic children...
Interventions for improving metabolic risk in overweight Latino youthJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USA
Int J Pediatr Obes 5:451-5. 2010..In conclusion, ST, CAST, and a modified carbohydrate nutrition program with separate parental classes were all successful components of the interventions that decreased obesity and related metabolic diseases...
Relation between acanthosis nigricans and insulin sensitivity in overweight Hispanic children at risk for type 2 diabetesHassan A Kobaissi
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Health Sciences Campus, 1540 Alcazar Street, Rm. 208-D, Los Angeles, CA 90033, USA
Diabetes Care 27:1412-6. 2004..In addition, scale scoring AN seems of minimal usefulness in clinically estimating the severity of insulin resistance over and above assessing the presence or absence of AN and calculating BMI...
Subclinical atherosclerosis in Latino youth: progression of carotid intima-media thickness and its relationship to cardiometabolic risk factorsClaudia M Toledo-Corral
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
J Pediatr 158:935-40. 2011..To assess carotid artery intima-media thickness (CIMT) change over 2 years in overweight Latino adolescents and examine its relationship to cardiometabolic risk...
Pubertal changes of insulin sensitivity, acute insulin response, and ?-cell function in overweight Latino youthLouise A Kelly
Department of Exercise Science, California Lutheran University, Los Angeles, CA, USA
J Pediatr 158:442-6. 2011..To examine changes in insulin sensitivity (SI), compensatory acute insulin response (AIR), and ?-cell function/disposition index (DI) across puberty in overweight Latino boys and girls...
A high-sugar/low-fiber meal compared with a low-sugar/high-fiber meal leads to higher leptin and physical activity levels in overweight Latina femalesDonna Spruijt-Metz
University of Southern California, Keck School of Medicine, USC IPR, 1000 S Fremont, Unit 8, Room 4101, Alhambra, CA 91803, USA
J Am Diet Assoc 109:1058-63. 2009..High-sugar meals sustain glucose and leptin levels longer, which may play an important role in modulating levels of physical activity in this group at high risk for obesity-related disease...
Effects of resistance training on insulin sensitivity in overweight Latino adolescent malesGabriel Q Shaibi
Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA 90033, USA
Med Sci Sports Exerc 38:1208-15. 2006..9+/-12.9% in controls (P<0.01). CONCLUSION: A twice-per-week 16-wk resistance training program can significantly increase insulin sensitivity in overweight Latino adolescent males independent of changes in body composition...
Feasibility of a home-based versus classroom-based nutrition intervention to reduce obesity and type 2 diabetes in Latino youthJaimie N Davis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Int J Pediatr Obes 2:22-30. 2007....
Cardiovascular fitness and the metabolic syndrome in overweight latino youthsGabriel Q Shaibi
Department of Biokinesiology and Physical Therapy, University of Southern California, Health Sciences Campus, Los Angeles, CA 90033, USA
Med Sci Sports Exerc 37:922-8. 2005..CONCLUSION: (.)VO(2max) is not independently associated with the metabolic syndrome or any individual feature in overweight youths of Latino ethnicity after controlling for differences in confounding variables...
Insulin-like growth factor-I is inversely related to adiposity in overweight Latino childrenClaudia M Toledo-Corral
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089 9073, USA
J Pediatr Endocrinol Metab 21:855-64. 2008..02, p = 0.85). Correlations with visceral and subcutaneous adipose tissue yielded similar results. These results demonstrate that IGF-I, IGFBP-1 and IGFBP-3 are all inversely related to adiposity in Hispanic children...
Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescentsMichael I Goran
Department of Preventive Medicine, Childhood Obesity Research Center, University of Southern California, Los Angeles, California, USA
Diabetes 59:3127-30. 2010..The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents...
Dietary fat intake and insulin resistance in black and white childrenMarc J Weigensberg
Department of Pediatrics, University of Southern California, Los Angeles, CA 90089, USA
Obes Res 13:1630-7. 2005..The mechanism(s) underlying the ethnic differences in the relationship between dietary fat intake and SI in children require further investigation...
Persistence of pre-diabetes in overweight and obese Hispanic children: association with progressive insulin resistance, poor beta-cell function, and increasing visceral fatMichael I Goran
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes 57:3007-12. 2008..To examine changes in risk factors in overweight and obese Hispanic children at high risk of developing type 2 diabetes...
CRP Is Related to Higher Leptin Levels in Minority Peripubertal Females Regardless of Adiposity LevelsDonna Spruijt-Metz
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 20:512-6. 2012..00) of the variance in leptin after adjusting %BF, TPS, ethnicity, habitual physical activity and SI. Hence, low-grade inflammation may contribute to prolonged leptin exposure and leptin resistance, even in healthy children...
Persistence of the metabolic syndrome and its influence on carotid artery intima media thickness in overweight Latino childrenClaudia M Toledo-Corral
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9073, United States
Atherosclerosis 206:594-8. 2009..The objective of this study was to examine the influence of persistence of the metabolic syndrome (Mets) and its individual components over a 3-year period on carotid intima media thickness (CIMT) in overweight Latino children...
Association between insulin sensitivity and post-glucose challenge plasma insulin values in overweight Latino youthMarc J Weigensberg
Department of Physiology and Biophysics, University of Southern California, Los Angeles, California 90089, USA
Diabetes Care 26:2094-9. 2003..The 2-h insulin may therefore be superior to fasting insulin as a single blood sample value for clinical or epidemiological estimates of SI, especially when combined with assessment of body composition...
Relationships between IGF-1 and IGFBP-1 and adiposity in obese African-American and Latino adolescentsTanya L Alderete
Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 19:933-8. 2011..These results demonstrate that the relationship between IGF-1 and SAAT as well as IGFBP-1 and HFF are different in African-American and Latino adolescents and may contribute to the higher IGF-1 levels in African-Americans...
Stress and abdominal fat: preliminary evidence of moderation by the cortisol awakening response in Hispanic peripubertal girlsCarrie J Donoho
Davis School of Gerontology, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 19:946-52. 2011..Similar to job stress in adults, school-related stress in children may contribute to central adiposity, especially for girls with high CAR...
Adiponectin independently predicts metabolic syndrome in overweight Latino youthGabriel Q Shaibi
College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, AZ 85069, USA
J Clin Endocrinol Metab 92:1809-13. 2007..Adiponectin may be important in the pathogenesis of insulin resistance and the metabolic syndrome in youth...
Predicting abdominal adipose tissue in overweight Latino youthGeoff D C Ball
University of Alberta, Edmonton, AB, Canada
Int J Pediatr Obes 1:210-6. 2006....
Frequency of hypoglycaemia during the intravenous glucose tolerance test in overweight childrenMartha L Cruz
Department of Health Promotion, College of Health Sciences, University of Texas at El Paso, El Paso, TX 79902, USA
Int J Pediatr Obes 2:122-5. 2007..5% subjects). In addition, only 1.9% of subjects (n=4) had plasma glucose<60 mg/dl at any time during the FSIVGTT. The frequency of hypoglycaemia during the insulin modified FSIVGTT is very low in overweight Hispanic youth...
Research Grants
- Guided Imagery Intervention for Obese Latino AdolescentsMarc Weigensberg; Fiscal Year: 2007..This could be an effective means of preventing both type 2 diabetes and cardiovascular disease in susceptible youth, thereby reducing both the suffering and costs associated with these diseases. ..
