Research Topics
| Kent A WeigelSummaryAffiliation: University of Wisconsin Country: USA Publications
| Collaborators |
Detail Information
Publications
Prospects for improving reproductive performance through genetic selectionKent A Weigel
Department of Dairy Science, University of Wisconsin, 1675 Observatory Drive, Madison, WI 53706, USA
Anim Reprod Sci 96:323-30. 2006..Such systems will allow selection of animals that can remain healthy and fertile while producing large quantities of milk...
Potential gains in lifetime net merit from genomic testing of cows, heifers, and calves on commercial dairy farmsK A Weigel
Department of Dairy Science, University of Wisconsin, Madison 53706, USA
J Dairy Sci 95:2215-25. 2012....
Genomic evaluations with many more genotypesPaul M Vanraden
Animal Improvement Programs Laboratory, USDA, Building 5 BARC West, Beltsville, MD 20705 2350, USA
Genet Sel Evol 43:10. 2011..Algorithms to combine different densities need to be efficient because numbers of genotyped animals and markers may continue to grow quickly...
Accuracy of direct genomic values derived from imputed single nucleotide polymorphism genotypes in Jersey cattleK A Weigel
Department of Dairy Science, University of Wisconsin, Madison, Wisconsin 53706, USA
J Dairy Sci 93:5423-35. 2010..San Diego, CA) in Jersey cattle. However, if fewer than 1,500 SNP are genotyped, the accuracy of DGV may be limited by errors in the imputed genotypes of selection candidates...
Prediction of unobserved single nucleotide polymorphism genotypes of Jersey cattle using reference panels and population-based imputation algorithmsK A Weigel
Department of Dairy Science, University of Wisconsin, Madison, Wisconsin 53706, USA
J Dairy Sci 93:2229-38. 2010..g., >40,000 SNP) from a reference population. Accurate imputation of high-density genotypes from inexpensive low- or medium-density platforms could greatly enhance the efficiency of whole-genome selection programs in dairy cattle...
Predictive ability of direct genomic values for lifetime net merit of Holstein sires using selected subsets of single nucleotide polymorphism markersK A Weigel
Department of Dairy Science, University of Wisconsin, Madison 53706, USA
J Dairy Sci 92:5248-57. 2009....
Application of support vector regression to genome-assisted prediction of quantitative traitsNanye Long
Department of Animal Sciences, University of Wisconsin, 1675 Observatory Dr, Animal Science Bldg, Madison, WI 53706, USA
Theor Appl Genet 123:1065-74. 2011..It is concluded that a nonlinear RBF kernel may be an optimal choice for SVR, especially when phenotypes to be predicted have a nonlinear dependency on genotypes, as it might have been the case in the wheat data...
Radial basis function regression methods for predicting quantitative traits using SNP markersNanye Long
Department of Animal Sciences, University of Wisconsin, Madison, WI 53706, USA
Genet Res (Camb) 92:209-25. 2010..Extension of Bayes A to include all additive, dominance and epistatic effects could improve its prediction accuracy. RBF I was generally better than RBF II, and was able to identify relevant SNPs in the toy example...
Predicting complex quantitative traits with Bayesian neural networks: a case study with Jersey cows and wheatDaniel Gianola
Dept of Animal Sciences, University of Wisconsin, Madison, WI 53706, USA
BMC Genet 12:87. 2011..ANNs are interesting candidates for analysis of traits affected by cryptic forms of gene action...
Long-term impacts of genome-enabled selectionNanye Long
Department of Animal Sciences, University of Wisconsin Madison, WI 53706, USA
J Appl Genet 52:467-80. 2011..Selection changed quantitative trait loci (QTL) allele frequencies and generated new but unfavorable LD for prediction. Family effects had a considerable contribution to GEBV accuracy in early generations of selection...
Semi-parametric genomic-enabled prediction of genetic values using reproducing kernel Hilbert spaces methodsGustavo de Los Campos
University of Wisconsin Madison, 1675 Observatory Drive, WI 53706, USA
Genet Res (Camb) 92:295-308. 2010....
Bayesian model averaging for evaluation of candidate gene effectsXiao Lin Wu
Department of Dairy Science, University of Wisconsin, Madison, WI 53706, USA
Genetica 138:395-407. 2010..Features of the method are demonstrated using a simulated data set with ten candidate genes under consideration...
Modeling relationships between calving traits: a comparison between standard and recursive mixed modelsEvangelina López de Maturana
Department of Animal Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA
Genet Sel Evol 42:1. 2010..All recursive models considered here postulate heterogeneous recursive relationships between GL and liabilities to CD and SB, and between liability to CD and liability to SB, depending on categories of GL phenotype...
Comparison of classification methods for detecting associations between SNPs and chick mortalityNanye Long
Department of Animal Sciences, University of Wisconsin, Madison, WI 53706, USA
Genet Sel Evol 41:18. 2009..Use of extreme samples seems to enhance the ability of feature selection procedures to select influential SNPs in genetic association studies...
Nonparametric methods for incorporating genomic information into genetic evaluations: an application to mortality in broilersOscar González-Recio
Departamento de Produccion Animal, E T S I Agrónomos Universidad Politécnica de Madrid, 28040 Madrid, Spain
Genetics 178:2305-13. 2008..Predictive ability, assessed by cross-validation, indicated advantages of the RKHS approach, where accuracy was increased from 25 to 150%, relative to other methods...
A primer on high-throughput computing for genomic selectionXiao Lin Wu
Department of Dairy Science, University of Wisconsin Madison, WI, USA
Front Genet 2:4. 2011..Eventually, HTC may change our view of data analysis as well as decision-making in the post-genomic era of selection programs in animals and plants, or in the study of complex diseases in humans...
Marker-assisted prediction of non-additive genetic valuesNanye Long
Department of Animal Sciences, University of Wisconsin Madison, 1675 Observatory Dr Animal Science Bldg, Madison, WI 53706, USA
Genetica 139:843-54. 2011....
Genome-assisted prediction of a quantitative trait measured in parents and progeny: application to food conversion rate in chickensOscar González-Recio
Department of Dairy Science, University of Wisconsin, Madison, WI 53706, USA
Genet Sel Evol 41:3. 2009..Bayes A and RKHS regression were equally accurate (_r(S)) = 0.27) when all 3481 SNPs were included in the model. However, RKHS with 400 pre-selected informative SNPs was more accurate than Bayes A with all SNPs...
Exploring biological relationships between calving traits in primiparous cattle with a Bayesian recursive modelEvangelina López de Maturana
Department of Animal Sciencs, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 181:277-87. 2009..The model indicated that gestations of approximately 274 days of length (3 days shorter than the average) would lead to the lowest CD and SB and confirmed the existence of an intermediate optimum of GL with respect to these traits...
