Research Topics
| K M WassumSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Transient extracellular glutamate events in the basolateral amygdala track reward-seeking actionsKate M Wassum
Department of Psychology, University of California, Los Angeles, CA 90095, USA
J Neurosci 32:2734-46. 2012..Such novel rapid glutamate recordings during instrumental performance identify a role for glutamatergic signaling within the BLA in instrumental reward-seeking actions...
International Narcotics Research Conference - 39th Annual MeetingKate M Wassum
University of California, Los Angeles, Los Angeles, CA 90095, USA
IDrugs 11:646-9. 2008
Distinct opioid circuits determine the palatability and the desirability of rewarding eventsK M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90024, USA
Proc Natl Acad Sci U S A 106:12512-7. 2009..Rather, changes in palatability and in the incentive value assigned to rewarding events seem to be mediated by distinct neural processes...
Disruption of endogenous opioid activity during instrumental learning enhances habit acquisitionK M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA
Neuroscience 163:770-80. 2009..These data suggest that an intact endogenous opioid system is necessary for normal goal-directed learning and more importantly, reveal that a compromised endogenous opioid system during learning enhances the habitual control of actions...
Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food rewardKate M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California 90024, USA
J Neurosci 31:1591-9. 2011....
Differential dependence of Pavlovian incentive motivation and instrumental incentive learning processes on dopamine signalingKate M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California 90024, USA
Learn Mem 18:475-83. 2011....
Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioningSean B Ostlund
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California 90024, USA
J Neurosci 31:200-7. 2011..Together, the results indicate that tonic DA contributes to the control of instrumental performance by conveying information about the costs and benefits of responding to different striatal subregions...
Research Grants
- Opioid and Glutamate Modulation of Reward Value During Goal-Directed BehaviorKATE WASSUM; Fiscal Year: 2007..Consequently, this research will inform not only our understanding of how the reward systems may be usurped by addictive drugs, but also research on potential pharmacotherapies. ..
