Shuxia Wang

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
    Shuxia Wang
    Department of Vascular Biology, Jerome H Holland Laboratory, American Red Cross, Rockville, Maryland 20855, USA
    J Cell Biochem 91:766-76. 2004
  2. ncbi Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-beta activation in mesangial cells
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, The Cell Adhesion and Matrix Research Center, University of Alabama, Birmingham 35294 0019, USA
    J Biol Chem 277:9880-8. 2002
  3. ncbi Expression of constitutively active cGMP-dependent protein kinase prevents glucose stimulation of thrombospondin 1 expression and TGF-beta activity
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diabetes 52:2144-50. 2003
  4. ncbi Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, The Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
    J Biol Chem 279:34311-22. 2004
  5. ncbi Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury
    Shu Liu
    Graduate Center for Nutritional Sciences, University of Kentucky, Wethington Bldg Rm 517, 900 S Limestone St, Lexington, KY 40536, USA
    Am J Physiol Renal Physiol 293:F1727-35. 2007

Collaborators

Detail Information

Publications5

  1. ncbi Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
    Shuxia Wang
    Department of Vascular Biology, Jerome H Holland Laboratory, American Red Cross, Rockville, Maryland 20855, USA
    J Cell Biochem 91:766-76. 2004
    ..These results indicate that TSP-1 binding to LRP-1 does not require prior or concomitant interaction with cell surface HSPG but suggest subsequent endocytosis requires high-affinity heparin-binding...
  2. ncbi Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-beta activation in mesangial cells
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, The Cell Adhesion and Matrix Research Center, University of Alabama, Birmingham 35294 0019, USA
    J Biol Chem 277:9880-8. 2002
    ..These results show that high glucose mediates increases in TSP1 expression and TSP1-dependent TGF-beta bioactivity through down-modulation of NO-cGMP-dependent protein kinase signaling...
  3. ncbi Expression of constitutively active cGMP-dependent protein kinase prevents glucose stimulation of thrombospondin 1 expression and TGF-beta activity
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diabetes 52:2144-50. 2003
    ....
  4. ncbi Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2
    Shuxia Wang
    Department of Pathology, Division of Molecular and Cellular Pathology, The Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
    J Biol Chem 279:34311-22. 2004
    ....
  5. ncbi Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury
    Shu Liu
    Graduate Center for Nutritional Sciences, University of Kentucky, Wethington Bldg Rm 517, 900 S Limestone St, Lexington, KY 40536, USA
    Am J Physiol Renal Physiol 293:F1727-35. 2007
    ..Type 1 diabetes onset further augmented the urinary albumin excretion and glomerular hypertrophy in the USF2 (Tg) mice. These findings suggest that overexpression of USF2 accelerates the development of diabetic nephropathy...