Research Topics
| Li WangSummaryAffiliation: University of Southern California Country: USA Publications
| Collaborators |
Detail Information
Publications
Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategyLi Wang
Molecular and Computational Biology, Department of Biology Sciences, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089 2910, USA
Genome Biol 9:R174. 2008..We discovered that lethality is more conserved at the module level than at the gene level and we identified several potentially 'new' cancer-related biological processes...
A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in DrosophilaLi Wang
Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA
BMC Genomics 10:220. 2009..Therefore, integrating RNAi screening results with other information, such as protein-protein interaction (PPI), may help to address these issues...
CGI: a new approach for prioritizing genes by combining gene expression and protein-protein interaction dataXiaotu Ma
Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089 2910, USA
Bioinformatics 23:215-21. 2007..Several integrative methods have been developed when a set of candidate genes for the phenotype is available. However, how to prioritize genes for phenotypes when no candidates are available is still a challenging problem...
Further understanding human disease genes by comparing with housekeeping genes and other genesZhidong Tu
Molecular and Computational Biology Program, University of Southern California, Los Angeles, California 90089, USA
BMC Genomics 7:31. 2006..Here we perform a comparative study on the features of human essential, disease, and other genes...
An integrative approach for causal gene identification and gene regulatory pathway inferenceZhidong Tu
Molecular and Computational Biology Program, University of Southern California, Los Angeles, USA
Bioinformatics 22:e489-96. 2006..New potential gene regulatory pathways are generated and presented as a global network. AVAILABILITY: Source code is available upon request...
