Research Topics
| Jianhua WangSummaryAffiliation: University of Miami Country: USA Publications
Research Grants
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Detail Information
Publications
Precorneal and pre- and postlens tear film thickness measured indirectly with optical coherence tomographyJianhua Wang
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
Invest Ophthalmol Vis Sci 44:2524-8. 2003..The postlens tear film is thicker than the precorneal and prelens tear films with soft contact lenses. The thickness of both pre- and postlens tear films appears to be independent of the investigated lens types...
Ultra-high resolution optical coherence tomography for imaging the anterior segment of the eyeJianhua Wang
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 1638 NW 10th Avenue, Miami, FL 33136, USA
Ophthalmic Surg Lasers Imaging 42:S15-27. 2011..The authors focused on the use of UHR-OCT for imaging of tear dynamics, contact lens interactions with the corneal surface, and in vivo histological diagnosis of disorders of the cornea, as well as the future direction in this field...
Dynamic distribution of artificial tears on the ocular surfaceJianhua Wang
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 1638 NW 10th Ave, McKnight Bldg, Room 506, Miami, FL 33136, USA
Arch Ophthalmol 126:619-25. 2008..To study the effects of artificial tear viscosity on tear film thickness, upper and lower tear menisci, and tear volume using optical coherence tomography...
Detection of magnetic particles in live DBA/2J mouse eyes using magnetomotive optical coherence tomographyJianhua Wang
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA
Eye Contact Lens 36:346-51. 2010..To demonstrate in vivo molecular imaging of the eye using spectral-domain magnetomotive optical coherence tomography (MMOCT)...
Correlations among upper and lower tear menisci, noninvasive tear break-up time, and the Schirmer testJianhua Wang
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Am J Ophthalmol 145:795-800. 2008..To determine the relationships among tear meniscus parameters, noninvasive tear break-up time (NITBUT), and the Schirmer test...
The watery eyeJianhua Wang
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA
Curr Allergy Asthma Rep 11:192-6. 2011..Recent advances in imaging technique are briefly discussed...
Relationships between central tear film thickness and tear menisci of the upper and lower eyelidsJianhua Wang
Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
Invest Ophthalmol Vis Sci 47:4349-55. 2006..To investigate the relationship between central tear film thickness (TFT) and tear menisci of the upper and lower eyelids using real-time optical coherence tomography (OCT)...
In situ visualization of tears on contact lens using ultra high resolution optical coherence tomographyJianhua Wang
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
Eye Contact Lens 35:44-9. 2009..To demonstrate the capability of directly visualizing the tear film on contact lenses using optical coherence tomography (OCT)...
Ultra-high resolution optical coherence tomography for differentiation of ocular surface squamous neoplasia and pterygiaJeremy Z Kieval
Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA
Ophthalmology 119:481-6. 2012..To assess the use of an ultra-high-resolution (UHR) optical coherence tomography (OCT) as an adjuvant diagnostic tool in distinguishing ocular surface squamous neoplasia (OSSN) and pterygia...
Reduced tear meniscus dynamics in dry eye patients with aqueous tear deficiencyYimin Yuan
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Am J Ophthalmol 149:932-938.e1. 2010..To measure the tear meniscus dynamics in aqueous tear deficiency dry eye patients using optical coherence tomography...
Extended scan depth optical coherence tomography for evaluating ocular surface shapeMeixiao Shen
Department of Ophthalmology, University of Miami, Bascom Palmer Eye Institute, 1638 NW 10th Avenue, Miami, Florida 33136, USA
J Biomed Opt 16:056007. 2011..The standard deviations of the height measurement within a 14-mm wide range were all less than 35 ?m. This work demonstrates the feasibility of using extended depth SD-OCT to perform noninvasive evaluation of the ocular surface shape...
Effect of blinking on tear volume after instillation of midviscosity artificial tearsJayachandra R Palakuru
Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Am J Ophthalmol 146:920-4. 2008..To determine by optical coherence tomography (OCT) the effect of blinking on ocular surface tear volume after instillation of artificial tears...
SD-OCT with prolonged scan depth for imaging the anterior segment of the eyeMeixiao Shen
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 1638 NW 10th Avenue, Miami, FL 33136, USA
Ophthalmic Surg Lasers Imaging 41:S65-9. 2010..The system was also tested in imaging accommodation of the same eye, demonstrating the feasibility of the novel approach for evaluating presbyopia/accommodation...
Ultra high-resolution anterior segment optical coherence tomography in the evaluation of anterior corneal dystrophies and degenerationsLejla M Vajzovic
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA
Ophthalmology 118:1291-6. 2011..To evaluate the clinical usefulness of a spectral-domain ultra high-resolution anterior segment optical coherence tomography (UHR OCT) in examination, diagnosis, and management of various anterior corneal dystrophies and degenerations...
Characterization of soft contact lens edge fitting using ultra-high resolution and ultra-long scan depth optical coherence tomographyMeixiao Shen
Departments of Ophthalmology, Bascom Palmer Eye Institute, Jacksonville, Florida, USA
Invest Ophthalmol Vis Sci 52:4091-7. 2011..To characterize the edge fitting of soft contact lenses using ultra-high resolution optical coherence tomography (UHR-OCT) and ultra-long scan depth optical coherence tomography (UL-OCT)...
Diagnosis and management of conjunctival and corneal intraepithelial neoplasia using ultra high-resolution optical coherence tomographyMohamed Abou Shousha
Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida, USA
Ophthalmology 118:1531-7. 2011..To report a novel diagnostic technique and a case series of conjunctival and corneal intraepithelial neoplasia (CCIN) diagnosed and followed up using prototype ultra high-resolution (UHR) optical coherence tomography (OCT)...
Micrometer-scale contact lens movements imaged by ultrahigh-resolution optical coherence tomographyLele Cui
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA
Am J Ophthalmol 153:275-283.e1. 2012..To dynamically evaluate contact lens movement and ocular surface shape using ultrahigh-resolution and ultralong-scan-depth optical coherence tomography (OCT)...
Use of ultra-high-resolution optical coherence tomography to detect in vivo characteristics of Descemet's membrane in Fuchs' dystrophyMohamed Abou Shousha
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
Ophthalmology 117:1220-7. 2010..2) To evaluate the use of DM characteristics and thickness in the diagnosis of Fuchs' dystrophy...
Entire contact lens imaged in vivo and in vitro with spectral domain optical coherence tomographyMeixiao Shen
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Eye Contact Lens 36:73-6. 2010..To demonstrate the capability of directly visualizing the entire ocular surface and the entire contact lens on the eye using spectral domain optical coherence tomography (SD-OCT)...
Effect of blinking on tear dynamicsJayachandra R Palakuru
Department of Ophthalmology, University of Rochester, Rochester, New York, USA
Invest Ophthalmol Vis Sci 48:3032-7. 2007..Optical coherence tomography (OCT) was used to study the impact of blinking on tear dynamics...
Repeated measurements of dynamic tear distribution on the ocular surface after instillation of artificial tearsJianhua Wang
Department of Ophthalmology, University of Rochester, NY 14642, USA
Invest Ophthalmol Vis Sci 47:3325-9. 2006..To determine the repeatability of real-time optical coherence tomography (OCT) measurements of tear film thickness (TFT) and variables of tear film menisci...
Corneal haze following disruption of epithelial basement membrane on ultra-high-resolution OCT following femtosecond LASIKPravin K Vaddavalli
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
J Refract Surg 28:72-4. 2012..To analyze in vivo structural properties of a case with interface haze that developed after femtosecond laser-assisted LASIK...
Atypical presentation of Salzmann nodular degeneration diagnosed with ultra-high-resolution optical coherence tomographyVolkan Hurmeric
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
Ophthalmic Surg Lasers Imaging 42:e122-5. 2011..UHR-OCT findings were consistent with Salzmann nodular degeneration. UHR-OCT can be used as an optical biopsy to diagnose atypical corneal degenerations without tissue sampling...
Upper and lower tear menisci on contact lensesJianhua Wang
Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Invest Ophthalmol Vis Sci 50:1106-11. 2009..The purpose of this study was to measure upper and lower tear menisci on contact lenses using real time optical coherence tomography (OCT)...
Persistent lamellar interface fluid with clear cornea after descemet stripping automated endothelial keratoplastyVolkan Hurmeric
From the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL and Institute of Vision and Optics, Department of Ophthalmology, University of Crete Medical School, Heraklion, Crete, Greece
Cornea 30:1485-7. 2011..To describe clinical properties of a patient with persistent interface fluid syndrome and clear graft, 3.5 years after Descemet stripping automated endothelial keratoplasty (DSAEK)...
Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imagingDexi Zhu
Wenzhou Medical College, School of Ophthalmology and Optometry, Wenzhou, Zhejiang 325000, China
J Biomed Opt 16:126006. 2011..Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way...
Slit-lamp-adapted ultra-high resolution OCT for imaging the posterior segment of the eyeHong Jiang
Division of Neuro ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Ophthalmic Surg Lasers Imaging 43:76-81. 2012..The authors described the system configuration, build-up, and test results of a small sample of human subjects. The comparison with a commercially available device was also included...
Repeated measurements of the anterior segment during accommodation using long scan depth optical coherence tomographyYimin Yuan
School of Ophthalmology and Optometry Y Y, F C, F L, Wenzhou Medical College, Wenzhou, China and Department of Ophthalmology Y Y, F C, M S, J W, Bascom Palmer Eye Institute Miller School of Medicine, University of Miami, Miami, FL
Eye Contact Lens 38:102-8. 2012..The aim was to determine the repeatability of ultralong scan depth spectral-domain optical coherence tomography (SD-OCT) measurements of the ocular anterior segment during accommodation...
In vivo structural characteristics of the femtosecond LASIK-induced opaque bubble layers with ultrahigh-resolution SD-OCTVolkan Hurmeric
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17 Street, Miami, FL, USA
Ophthalmic Surg Lasers Imaging 41:S109-13. 2010..UHR-OCT imaging can be used to demonstrate the structural characteristics of OBL. It has the potential to be used to predict incomplete lamellar flap dissections in patients with opaque bubble layers...
Photorefractive keratectomy in the cat eye: biological and optical outcomesLana J Nagy
Department of Ophthalmology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
J Cataract Refract Surg 33:1051-64. 2007..To quantify optical and biomechanical properties of the feline cornea before and after photorefractive keratectomy (PRK) and assess the relative contribution of different biological factors to refractive outcome...
In vivo morphologic characteristics of Salzmann nodular degeneration with ultra-high-resolution optical coherence tomographyVolkan Hurmeric
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Am J Ophthalmol 151:248-56.e2. 2011..To examine the in vivo morphologic properties of Salzmann nodular degeneration with ultra-high-resolution optical coherence tomography (OCT)...
Intraoperative use of three-dimensional spectral-domain optical coherence tomographyTakeshi Ide
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
Ophthalmic Surg Lasers Imaging 41:250-4. 2010..To develop a prototype three-dimensional anterior segment spectral-domain optical coherence tomography (SD-OCT) device and demonstrate the feasibility of its use in the operating room...
Epithelial ingrowth after Descemet stripping automated endothelial keratoplasty: description of cases and assessment with anterior segment optical coherence tomographyLeejee H Suh
Bascom Palmer Eye Institute, Miami, FL 33136, USA
Cornea 30:528-34. 2011..To describe 5 cases of epithelial ingrowth after Descemet stripping automated endothelial keratoplasty (DSAEK) and the use of anterior segment optical coherence tomography (AS-OCT) to describe the areas of ingrowth...
Three-dimensional spectral domain optical coherence tomography of a clear corneal cataract incisionTheodore Leng
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
Ophthalmic Surg Lasers Imaging 39:S132-4. 2008..SD-OCT can be used to analyze clear corneal incisions to determine optimal wound construction technique and geometry as they relate to the prevention of complications such as postoperative wound leak, infection, and epithelial ingrowth...
Tear menisci after overnight contact lens wearAizhu Tao
School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China
Optom Vis Sci 88:1433-8. 2011..To determine the effect of overnight wear of contact lenses (CL) on tear meniscus, tear film stability, and subjective comfort...
Comparison of corneal thickness measured with optical coherence tomography, ultrasonic pachymetry, and a scanning slit methodJoseph Thomas
Department of Ophthalmology, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio, USA
J Refract Surg 22:671-8. 2006..All instruments indicated corneal swelling and recovery during the first postoperative week and thickening at 1 month...
Cochlin, intraocular pressure regulation and mechanosensingManik Goel
Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
PLoS ONE 7:e34309. 2012..Taken together with previous studies, we show cochlin is involved in regulation of intraocular pressure in DBA/2J potentially through mechanosensing of the shear stress...
Improving image segmentation performance and quantitative analysis via a computer-aided grading methodology for optical coherence tomography retinal image analysisDelia Cabrera DeBuc
University of Miami, Miller School of Medicine, Bascom Palmer Eye Institute, Miami, Florida 33136, USA
J Biomed Opt 15:046015. 2010..Our methodology facilitates a more robust and localized quantification of the retinal structure in normal healthy controls and patients with clinically significant intraretinal features...
Evaluation of a transgenic mouse model of multiple sclerosis with noninvasive methodsMabel Enriquez-Algeciras
Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
Invest Ophthalmol Vis Sci 52:2405-11. 2011..To evaluate the ND4 transgenic mouse model of multiple sclerosis using noninvasive methods...
Diurnal variation of upper and lower tear menisciMeixiao Shen
School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China
Am J Ophthalmol 145:801-6. 2008..To determine diurnal variation of tear menisci around upper and lower eyelids in normal subjects...
Biometric measurement of the mouse eye using optical coherence tomography with focal plane advancementXiangtian Zhou
School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical College, Wenzhou, Zhejiang, 325003, China
Vision Res 48:1137-43. 2008..To demonstrate that high-resolution biometry is possible in mouse eyes in vivo, using real-time OCT with focal plane advancement by a stepper motor...
Corneal light backscatter measured by optical coherence tomography after LASIKJianhua Wang
Dept of Ophthalmology, Box 314, University of Rochester Medical Center, Rochester, NY 14642, USA
J Refract Surg 22:604-10. 2006..To objectively quantify corneal light backscatter after LASIK using optical coherence tomography (OCT)...
Relation between optical coherence tomography and optical pachymetry measurements of corneal swelling induced by hypoxiaJianhua Wang
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
Am J Ophthalmol 134:93-8. 2002..Although both instruments are correlated highly in all conditions tested, OCT may overestimate corneal thickness in normal and edematous corneas...
Noncontact measurements of central corneal epithelial and flap thickness after laser in situ keratomileusisJianhua Wang
School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
Invest Ophthalmol Vis Sci 45:1812-6. 2004..To investigate the changes in the epithelium and flap after laser in situ keratomileusis (LASIK), when measured with optical coherence tomography (OCT)...
Central corneal thickness and corneal hysteresis during corneal swelling induced by contact lens wear with eye closureFan Lu
School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China
Am J Ophthalmol 143:616-22. 2007..To determine if corneal hysteresis (CH) was associated with increased central corneal thickness (CCT) induced by wearing soft contact lenses during eye closure...
Objective measurements of corneal light-backscatter during corneal swelling, by optical coherence tomographyJianhua Wang
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
Invest Ophthalmol Vis Sci 45:3493-8. 2004..This study has demonstrated that corneal backscattered light increased in the anterior and posterior layers of the cornea during corneal swelling induced by contact lens wear and eye closure...
Isolation and analysis of water stress induced genes in maize seedlings by subtractive PCR and cDNA macroarrayJun Zheng
State Key Laboratory of Agrobiotechnology, National Plant Gene Research Center Beijing, China Agricultural University, Beijing 100094, China
Plant Mol Biol 55:807-23. 2004..A set of transcripts has been identified, which have significantly increased expression and probably involved in water stress signaling pathway based on data analysis...
Research Grants
- Characterization of Tear DynamicsJianhua Wang; Fiscal Year: 2007..g. dry eye). ..
