Research Topics
| Chuanfeng WangSummaryAffiliation: University of Minnesota Country: USA Publications
Research Grants
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Detail Information
Publications
The lighter side of BDNFEmily E Noble
Veterans Affairs Medical Center, GRECC 11G, One Veterans Drive, Minneapolis, MN, USA
Am J Physiol Regul Integr Comp Physiol 300:R1053-69. 2011....
Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditureChuanfeng Wang
Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Brain Res 1336:66-77. 2010..In conclusion, VMH BDNF reduces body weight by decreasing food intake and increasing EE consequent to increased SPA and RMR, suggesting that the VMH is an important site of BDNF action to influence energy balance...
Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat dietChuanfeng Wang
Veterans Affairs Medical Center, Research Service 151, One Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 298:R1320-32. 2010..These BDNF effects were greatest in the H body fat group. These data indicate that BDNF reduced HFD-induced obesity and metabolic syndrome-like measures, and the animals with the most body fat had the most significant response to BDNF...
Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intakeChuanfeng Wang
Veterans Affairs Medical Center, Research Service 151, One Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 293:R1003-12. 2007..Furthermore, BDNF appears to interact with NPY in its anorectic actions, although a direct effect on NPY remains to be established...
Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rateChuanfeng Wang
Veterans Affairs Medical Center, Research Service 151, One Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 293:R992-1002. 2007..These data suggest that the PVN is an important site of BDNF action to influence energy balance...
Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intakeChuanfeng Wang
Veterans Affairs Medical Center, Research Service 151 One Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 293:R1037-45. 2007..Furthermore, the anorectic effects of BDNF in this site appear to be mediated by NPY. These data suggest that the VMH is an important site of action for BDNF in its effects on energy metabolism...
Urocortin in the lateral septal area modulates feeding induced by orexin A in the lateral hypothalamusChuanfeng Wang
Veterans Affairs Medical Center, Geriatric, Research, Education and Clinical Center and Research Service, Minneapolis 55417, USA
Am J Physiol Regul Integr Comp Physiol 283:R358-67. 2002..These data define the LSi as an important site for UCN-induced anorexia and indicate that LSi UCN may influence orexin A feeding signals in the LH...
Urocortin in the hypothalamic PVN increases leptin and affects uncoupling proteins-1 and -3 in ratsCatherine M Kotz
Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 282:R546-51. 2002....
Evaluation of a quantitative magnetic resonance imaging system for whole body composition analysis in rodentsJoshua P Nixon
Minnesota Craniofacial Research Training Program, School of Dentistry, University of Minnesota, Minneapolis, Minnesota, USA
Obesity (Silver Spring) 18:1652-9. 2010..Despite these caveats, we conclude that the EchoMRI QMR system offers a fast in vivo method of body composition analysis, well correlated to but with greater overall precision than CCA...
Diminished feeding responsiveness to orexin A (hypocretin 1) in aged rats is accompanied by decreased neuronal activationCatherine M Kotz
Veterans Affairs Medical Center, GRECC 11G, One Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Regul Integr Comp Physiol 289:R359-R366. 2005..These data suggest that delayed and diminished feeding responses in old animals may be due to ineffective neural signaling and implicate the orexin A network as one feeding system affected by aging...
Feeding and activity induced by orexin A in the lateral hypothalamus in ratsCatherine M Kotz
Veterans Affairs Medical Center, One Veterans Drive, Research Service 151, Minneapolis, MN 55417, USA
Regul Pept 104:27-32. 2002..These data show that LH orexin A stimulation of feeding is not always coincident with increased activity, suggesting that feeding induced by LH-injected orexin A is not consequent to enhanced arousal...
Orexin A (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in ratsKohji Kiwaki
Endocrine Research Unit, Joseph 5-194, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA
Am J Physiol Endocrinol Metab 286:E551-9. 2004..Thus orexin A can act in PVN to increase nonfeeding-associated physical activity, suggesting that this neuropeptide might be a mediator of NEAT...
Peptides that regulate food intake: regional, metabolic, and circadian specificity of lateral hypothalamic orexin A feeding stimulationAndrew J Thorpe
Veterans Affairs Medical Center and Minnesota Obesity Center, Minneapolis 55417, USA
Am J Physiol Regul Integr Comp Physiol 284:R1409-17. 2003..These data suggest that the rostral LH is the only region of the LH sensitive to the injection of OX-A, and the metabolic status of the animal at the time of injection may influence the feeding response to OX-A...
Novel peptide-peptide cooperation may transform feeding behaviorAbba J Kastin
Veterans Affairs Medical Center and Tulane University School of Medicine, 1601 Perdido Street, New Orleans, LA 70112 1262, USA
Peptides 23:2189-96. 2002..Such a novel interaction between two peptides at the BBB opens new approaches for general study of the dynamic regulatory role of the BBB in brain-body communication as well as the specific study of obesity...
Caloric restriction and physical activity in zebrafish (Danio rerio)Colleen M Novak
Endocrine Research Unit, Mayo Clinic and Mayo Foundation, St Mary s Hospital, Rochester, MN 55905, USA
Neurosci Lett 383:99-104. 2005..Thus, the association between negative energy balance and reductions in PA occurs across genera in biology and is associated with predictable neurological changes in brain gene expression...
Research Grants
- Brain-derived neurotrophic factor induced weight loss: neural mechanismsChuanfeng Wang; Fiscal Year: 2009....
- Brain-derived neurotrophic factor induced weight loss: neural mechanismsChuanfeng Wang; Fiscal Year: 2010....
