Research Topics
| EVE Y VAN CAUTERSummaryAffiliation: University of Chicago Country: USA Publications
Research Grants
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Detail Information
Publications
Alterations of circadian rhythmicity and sleep in aging: endocrine consequencesE Van Cauter
Department of Medicine, University of Chicago, Ill 60637, USA
Horm Res 49:147-52. 1998....
Reciprocal interactions between the GH axis and sleepEve Van Cauter
Department of Medicine, MC 1027, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Growth Horm IGF Res 14:S10-7. 2004....
Impact of sleep and sleep loss on neuroendocrine and metabolic functionEve Van Cauter
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Horm Res 67:2-9. 2007..This trend toward shorter sleep times has occurred over the same time period as the dramatic increases in the prevalence of obesity and diabetes...
Sleep and the epidemic of obesity in children and adultsEve Van Cauter
Department of Medicine, MC1027, University of Chicago, 5841 S Maryland Avenue Chicago, Illinois 60637, USA
Eur J Endocrinol 159:S59-66. 2008..Altogether, the evidence points to a possible role of decreased sleep duration in the current epidemic of obesity...
Metabolic consequences of sleep and sleep lossEve Van Cauter
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Sleep Med 9:S23-8. 2008....
Role of sleep and sleep loss in hormonal release and metabolismRachel Leproult
Department of Medicine, University of Chicago, Chicago, Ill, USA
Endocr Dev 17:11-21. 2010..Avoiding sleep deprivation may help to prevent the development of obesity, particularly in children...
Interrelationships between growth hormone and sleepE Van Cauter
Department of Medicine, University of Chicago, Illinois 60637, USA
Growth Horm IGF Res 10:S57-62. 2000..Pharmacological stimulation of SW sleep results in increased GH release, and compounds that increase SW sleep may therefore represent a novel class of GH secretagogues...
Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy menE Van Cauter
Department of Medicine, MC 1027, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
JAMA 284:861-8. 2000..In young adults, sleep affects the regulation of growth hormone (GH) and cortisol. The relationship between decreased sleep quality in older adults and age-related changes in the regulation of GH and cortisol is unknown...
Sleep as a mediator of the relationship between socioeconomic status and health: a hypothesisE Van Cauter
Department of Medicine, University of Chicago, IL 60637, USA
Ann N Y Acad Sci 896:254-61. 1999..These results indicate that sleep loss can increase the "allostatic load" and facilitate the development of chronic conditions, such as obesity, diabetes, and hypertension, which have an increased prevalence in low SES groups...
Sex differences in nocturnal growth hormone and prolactin secretion in healthy older adults: relationships with sleep EEG variablesFederica Latta
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Sleep 28:1519-24. 2005..Improvements in the homeostatic control of sleep could have hormonal benefits in older adults...
Relationships between sleep disordered breathing and glucose metabolism in polycystic ovary syndromeEsra Tasali
Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 91:36-42. 2006..CONCLUSION: PCOS is associated with poor sleep quality, daytime sleepiness, and increased risk for OSA. Insulin levels and measures of glucose tolerance in PCOS are strongly correlated with the risk and severity of OSA...
Impact of carbohydrate-rich meals on plasma epinephrine levels: dysregulation with agingPlamen Penev
Section of Endocrinology, University of Chicago, MC 1027, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 90:6198-206. 2005....
Impact of untreated obstructive sleep apnea on glucose control in type 2 diabetesRenee S Aronsohn
Department of Medicine, MC 1027, University of Chicago, Chicago, IL 60637, USA
Am J Respir Crit Care Med 181:507-13. 2010..However, it is not known whether the severity of OSA is a predictor of glycemic control in patients with diabetes...
Loneliness and health: potential mechanismsJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
Psychosom Med 64:407-17. 2002..Two studies using cross-sectional designs explored four possible mechanisms by which loneliness may have deleterious effects on health: health behaviors, cardiovascular activation, cortisol levels, and sleep...
Association between sleep and blood pressure in midlife: the CARDIA sleep studyKristen L Knutson
Department of Health Studies, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Arch Intern Med 169:1055-61. 2009..Our objective was to examine both cross-sectional and longitudinal associations between objectively measured sleep and BP...
Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phaseOrfeu M Buxton
Department of Medicine, Section of Endocrinology, University of Chicago, Chicago, IL 60637, USA
Am J Physiol Regul Integr Comp Physiol 284:R714-24. 2003....
Impact of obstructive sleep apnea on insulin resistance and glucose tolerance in women with polycystic ovary syndromeEsra Tasali
Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 93:3878-84. 2008..Obstructive sleep apnea (OSA) has been linked to metabolic dysfunction. We studied women with and without PCOS to determine the extent to which OSA is responsible for insulin resistance and glucose intolerance in PCOS...
Associations between sleep loss and increased risk of obesity and diabetesKristen L Knutson
Department of Health Studies, University of Chicago, Chicago, IL 60637, USA
Ann N Y Acad Sci 1129:287-304. 2008..Consistent with the laboratory evidence, multiple epidemiologic studies have shown an association between short sleep and higher body mass index after controlling for a variety of possible confounders...
Obstructive sleep apnea and type 2 diabetes: interacting epidemicsEsra Tasali
University of Chicago, Department of Medicine, 5841 S Maryland Ave, MC 6026, Chicago, IL 60637, USA
Chest 133:496-506. 2008..A better understanding of the relationship between OSA and type 2 diabetes may have important public health implications...
Trends in the prevalence of short sleepers in the USA: 1975-2006Kristen L Knutson
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Sleep 33:37-45. 2010..To determine (1) whether short sleep has increased over 31 years; (2) whether trends in short sleep differed by employment status; (3) which sociodemographic factors predict short sleep; and (4) how short sleepers spend their time...
The metabolic consequences of sleep deprivationKristen L Knutson
Department of Medicine, University of Chicago, 5841 S Maryland Ave, MC 1027, Chicago, IL 60637, USA
Sleep Med Rev 11:163-78. 2007..The present article reviews the current evidence in support of these three mechanisms that might link short sleep and increased obesity and diabetes risk...
Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older menRachel Leproult
Centre d Etude des Rythmes Biologiques CERB and Laboratoire de Physiologie, Universite Libre de Bruxelles, Brussels, Belgium
Clin Endocrinol (Oxf) 63:298-304. 2005..This study aims to determine whether the potent melatonin agonist agomelatine (S-20098) is capable of phase-shifting overt circadian rhythms in older adults...
Estimating cardiac autonomic activity during sleep: impedance cardiography, spectral analysis, and Poincaré plotsHelen J Burgess
Research Laboratory on Sleep, Chronobiology and Neuroendocrinology, Section of Endocrinology, Department of Medicine, University of Chicago, Chicago, IL, USA
Clin Neurophysiol 115:19-28. 2004..To compare noninvasive measures of cardiac autonomic activity during sleep...
Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitusKristen L Knutson
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Arch Intern Med 166:1768-74. 2006..Combined with existing evidence linking sleep loss to increased diabetes risk, these data suggest that optimizing sleep duration and quality should be tested as an intervention to improve glucose control in patients with type 2 diabetes...
Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropinKarine Spiegel
Department of Medicine, MC 1027, University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 89:5762-71. 2004..During the study with 8-h bedtimes, hormonal and metabolic parameters were intermediate between those observed with 4-h and 12-h bedtimes. In conclusion, sleep modulates a major component of the neuroendocrine control of appetite...
Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelatedRachel Leproult
Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
Am J Physiol Regul Integr Comp Physiol 284:R280-90. 2003..These findings indicate that sleep deprivation has highly reproducible, but independent, effects on brain mechanisms controlling subjective and objective alertness...
Sex differences in delta and alpha EEG activities in healthy older adultsFederica Latta
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Sleep 28:1525-34. 2005....
Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetiteKarine Spiegel
University of Chicago, Chicago, Illinois, USA
Ann Intern Med 141:846-50. 2004..CONCLUSIONS: Short sleep duration in young, healthy men is associated with decreased leptin levels, increased ghrelin levels, and increased hunger and appetite...
Slow-wave sleep and the risk of type 2 diabetes in humansEsra Tasali
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 105:1044-9. 2008..Furthermore, our data suggest that reduced sleep quality with low levels of SWS, as occurs in aging and in many obese individuals, may contribute to increase the risk of type 2 diabetes...
Research Grants
- Sleep Disturbance as a Nontraditional Risk Factor in CKDEve Van Cauter; Fiscal Year: 2007..abstract_text> ..
- EXTENDED WORK SCHEDULE AND HEALTH: ROLE OF SLEEP LOSSEve Van Cauter; Fiscal Year: 2006..The results of the proposed studies are expected to provide an estimation of sleep loss and circadian disruption as risk factors for the health and well-being of many Americans who work long and/or irregular hours. ..
- Cardiometabolic Risk of Shift Work: Sleep Loss vs. Circadian DisruptionEve Van Cauter; Fiscal Year: 2009..The overall goal of this project is to define the respective roles of circadian misalignment versus sleep loss in the elevated cardiometabolic risk of shift work. ..
- Cardiometabolic Risk of Shift Work: Sleep Loss vs. Circadian DisruptionEve Van Cauter; Fiscal Year: 2010..The overall goal of this project is to define the respective roles of circadian misalignment versus sleep loss in the elevated cardiometabolic risk of shift work. ..
- SLEEP & CIRCADIAN RHYTHMICITY IN GLUCOSE REGULATIONEve Van Cauter; Fiscal Year: 1993....
- SLEEP AND CIRCADIAN RHYTHMICITY IN GLUCOSE REGULATIONEve Van Cauter; Fiscal Year: 2002....
- Sleep Disturbance as a Nontraditional Risk Factor in CKDEve Van Cauter; Fiscal Year: 2010..abstract_text> ..
