Research Topics
| Cole TrapnellSummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
TopHat: discovering splice junctions with RNA-SeqCole Trapnell
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
Bioinformatics 25:1105-11. 2009..TopHat is an efficient read-mapping algorithm designed to align reads from an RNA-Seq experiment to a reference genome without relying on known splice sites...
How to map billions of short reads onto genomesCole Trapnell
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA
Nat Biotechnol 27:455-7. 2009..Mapping the vast quantities of short sequence fragments produced by next-generation sequencing platforms is a challenge. What programs are available and how do they work?..
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationCole Trapnell
Department of Computer Science, University of Maryland, College Park, Maryland, USA
Nat Biotechnol 28:511-5. 2010..These results suggest that Cufflinks can illuminate the substantial regulatory flexibility and complexity in even this well-studied model of muscle development and that it can improve transcriptome-based genome annotation...
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeBen Langmead
Center for Bioinformatics and Computational Biology, Institute for Advanced Computer Studies, University of Maryland, College Park, MD 20742, USA
Genome Biol 10:R25. 2009..Multiple processor cores can be used simultaneously to achieve even greater alignment speeds. Bowtie is open source (http://bowtie.cbcb.umd.edu)...
Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99ASteven L Salzberg
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
BMC Genomics 9:204. 2008..We report here on the complete genome sequence of strain PXO99A and its comparison to two previously sequenced strains, KACC10331 and MAFF311018, which are highly similar to one another...
High-throughput sequence alignment using Graphics Processing UnitsMichael C Schatz
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA
BMC Bioinformatics 8:474. 2007....
