John D Tompkins

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. ncbi Exocytotic release of ATP and activation of P2X receptors in dissociated guinea pig stellate neurons
    John D Tompkins
    University of Vermont, College of Medicine, Dept of Anatomy and Neurobiology, Burlington, VT 05405, USA
    Am J Physiol Cell Physiol 291:C1062-71. 2006
  2. ncbi Identification of intracellular signaling cascades mediating the PACAP-induced increase in guinea pig cardiac neuron excitability
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 36:292-8. 2008
  3. ncbi VIP and PACAP effects on mouse major pelvic ganglia neurons
    John D Tompkins
    Departments of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 42:390-6. 2010
  4. ncbi Ca2+ influx, but not Ca2+ release from internal stores, is required for the PACAP-induced increase in excitability in guinea pig intracardiac neurons
    John D Tompkins
    Department of Anatomy and Neurobiology, University of Vermont, Burlington, VT 05405, USA
    J Neurophysiol 95:2134-42. 2006
  5. ncbi Enhancement of Ih, but not inhibition of IM, is a key mechanism underlying the PACAP-induced increase in excitability of guinea pig intrinsic cardiac neurons
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 297:R52-9. 2009
  6. ncbi Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Physiol 582:87-93. 2007
  7. ncbi Calcium-induced calcium release regulates action potential generation in guinea-pig sympathetic neurones
    Sarah A Locknar
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    J Physiol 555:627-35. 2004
  8. ncbi Calcium influx through channels other than voltage-dependent calcium channels is critical to the pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea pig cardiac neurons
    Jean C Hardwick
    Department of Biology, Ithaca College, Ithaca, NY 14850, USA
    Ann N Y Acad Sci 1070:317-21. 2006
  9. ncbi Electrophysiological effects of tachykinin agonists on sympathetic ganglia of spontaneously hypertensive rats
    John D Tompkins
    Department of Pharmacology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-1708, USA
    Auton Neurosci 97:26-34. 2002

Collaborators

Detail Information

Publications9

  1. ncbi Exocytotic release of ATP and activation of P2X receptors in dissociated guinea pig stellate neurons
    John D Tompkins
    University of Vermont, College of Medicine, Dept of Anatomy and Neurobiology, Burlington, VT 05405, USA
    Am J Physiol Cell Physiol 291:C1062-71. 2006
    ..These results suggest that ASTICs are mediated by vesicular release of ATP and activation of P2X receptors...
  2. ncbi Identification of intracellular signaling cascades mediating the PACAP-induced increase in guinea pig cardiac neuron excitability
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 36:292-8. 2008
    ..We conclude that the activation of signaling cascades downstream of cAMP mediate the PACAP-induced increase in cardiac neuron excitability...
  3. ncbi VIP and PACAP effects on mouse major pelvic ganglia neurons
    John D Tompkins
    Departments of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 42:390-6. 2010
    ..The results suggest that VIP has a role in the neural control of pelvic organ function and activation of VPAC and/or PAC1 receptors can modulate the activity of the autonomic neurons innervating pelvic organs...
  4. ncbi Ca2+ influx, but not Ca2+ release from internal stores, is required for the PACAP-induced increase in excitability in guinea pig intracardiac neurons
    John D Tompkins
    Department of Anatomy and Neurobiology, University of Vermont, Burlington, VT 05405, USA
    J Neurophysiol 95:2134-42. 2006
    ....
  5. ncbi Enhancement of Ih, but not inhibition of IM, is a key mechanism underlying the PACAP-induced increase in excitability of guinea pig intrinsic cardiac neurons
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 297:R52-9. 2009
    ....
  6. ncbi Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability
    John D Tompkins
    Department of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Physiol 582:87-93. 2007
    ..We hypothesize that in vivo PACAP released during preganglionic firing may modulate neurotransmission within the intrinsic cardiac ganglia...
  7. ncbi Calcium-induced calcium release regulates action potential generation in guinea-pig sympathetic neurones
    Sarah A Locknar
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    J Physiol 555:627-35. 2004
    ....
  8. ncbi Calcium influx through channels other than voltage-dependent calcium channels is critical to the pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea pig cardiac neurons
    Jean C Hardwick
    Department of Biology, Ithaca College, Ithaca, NY 14850, USA
    Ann N Y Acad Sci 1070:317-21. 2006
    ..Exposure to a Ca2+-deficient solution did not deplete [Ca2+]i stores but did eliminate the PACAP-induced increase in excitability. We postulate that Ca2+ influx is required for the PACAP-induced increase in excitability...
  9. ncbi Electrophysiological effects of tachykinin agonists on sympathetic ganglia of spontaneously hypertensive rats
    John D Tompkins
    Department of Pharmacology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-1708, USA
    Auton Neurosci 97:26-34. 2002
    ..In conclusion, SHRs are more responsive to ganglion stimulation by NK1 agonists due to a greater number of responsive cells within the SCG rather than an enhanced responsiveness of individual neurons...