D A Tipton

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells
    D A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, 894 Union Avenue, TN 38163, Memphis, USA
    Toxicol In Vitro 17:301-10. 2003
  2. ncbi Effects of a hindered amine light stabilizer and a UV light absorber used in maxillofacial elastomers on human gingival epithelial cells and fibroblasts
    David A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Prosthet Dent 100:220-31. 2008
  3. ncbi Effect of a cyclooxygenase-2 inhibitor on interleukin-1beta-stimulated activation of the transcription factor nuclear factor-kappa B in human gingival fibroblasts
    David A Tipton
    Dental Research Center and Department of Periodontology, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontol 78:542-9. 2007
  4. ncbi Effect of myrrh oil on IL-1beta stimulation of NF-kappaB activation and PGE(2) production in human gingival fibroblasts and epithelial cells
    D A Tipton
    Dental Research Center and Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Toxicol In Vitro 20:248-55. 2006
  5. ncbi Role of the c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblasts
    David A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontol 75:360-9. 2004
  6. ncbi Cyclooxygenase-2 inhibitors decrease interleukin-1beta-stimulated prostaglandin E2 and IL-6 production by human gingival fibroblasts
    David A Tipton
    Department of Periodontology, The University of Tennessee Health Science Center, College of Dentistry, Memphis, TN 38163, USA
    J Periodontol 74:1754-63. 2003
  7. ncbi Statins regulate interleukin-1?-induced RANKL and osteoprotegerin production by human gingival fibroblasts
    S H Stein
    Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontal Res 46:483-90. 2011
  8. ncbi Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, osteoprotegerin and interleukin-6
    D A Tipton
    Department of Bioscience Research, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontal Res 46:39-47. 2011
  9. ncbi Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1beta production by human monocytes
    D A Tipton
    Department of Bioscience Research, College of Dentistry, The University of Tennessee Health Science Center, 62 South Dunlap Street, Memphis, TN 38163, USA
    Toxicol In Vitro 24:921-7. 2010
  10. ncbi Effect of cannabidiol on human gingival fibroblast extracellular matrix metabolism: MMP production and activity, and production of fibronectin and transforming growth factor ?
    S Y Rawal
    College of Dentistry Department of Periodontology Department of Bioscience Research College of Medicine Department of Molecular Sciences, The University of Tennessee Health Science Center, Memphis, TN, USA
    J Periodontal Res 47:320-9. 2012

Research Grants

  1. CELLULAR AND MOLECULAR TARGETING OF TMJ DESTRUCTION
    DAVID TIPTON; Fiscal Year: 2002

Collaborators

Detail Information

Publications10

  1. ncbi In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells
    D A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, 894 Union Avenue, TN 38163, Memphis, USA
    Toxicol In Vitro 17:301-10. 2003
    ..0025% MO, probably reflective of loss of viability. At subtoxic MO levels (0.00001-0.001%), there was a significant reduction of IL-1beta-stimulated IL-6 and IL-8 production by fibroblasts, but not by epithelial cells...
  2. ncbi Effects of a hindered amine light stabilizer and a UV light absorber used in maxillofacial elastomers on human gingival epithelial cells and fibroblasts
    David A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Prosthet Dent 100:220-31. 2008
    ..HALS inhibits polymer degradation and UVA dissipates UV radiation. Their effects on oral cells are unknown...
  3. ncbi Effect of a cyclooxygenase-2 inhibitor on interleukin-1beta-stimulated activation of the transcription factor nuclear factor-kappa B in human gingival fibroblasts
    David A Tipton
    Dental Research Center and Department of Periodontology, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontol 78:542-9. 2007
    ..The purpose of this study was to determine whether NS-398 inhibited phosphorylation of IkappaB and NF-kappaB activation...
  4. ncbi Effect of myrrh oil on IL-1beta stimulation of NF-kappaB activation and PGE(2) production in human gingival fibroblasts and epithelial cells
    D A Tipton
    Dental Research Center and Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Toxicol In Vitro 20:248-55. 2006
    ..Supported by NIDCR DE-0725.)...
  5. ncbi Role of the c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblasts
    David A Tipton
    Dental Research Center, Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontol 75:360-9. 2004
    ....
  6. ncbi Cyclooxygenase-2 inhibitors decrease interleukin-1beta-stimulated prostaglandin E2 and IL-6 production by human gingival fibroblasts
    David A Tipton
    Department of Periodontology, The University of Tennessee Health Science Center, College of Dentistry, Memphis, TN 38163, USA
    J Periodontol 74:1754-63. 2003
    ..The objective of this study was to determine the effects of COX-2 inhibitors on amounts of PGE2 and IL-6 made by IL-1beta-stimulated gingival fibroblasts...
  7. ncbi Statins regulate interleukin-1?-induced RANKL and osteoprotegerin production by human gingival fibroblasts
    S H Stein
    Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontal Res 46:483-90. 2011
    ..The purpose of this study was to evaluate OPG and RANKL production in resting and interleukin-1? (IL-1?)-activated human gingival fibroblasts (HGFs), and to determine the effect of statins on their production...
  8. ncbi Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, osteoprotegerin and interleukin-6
    D A Tipton
    Department of Bioscience Research, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Periodontal Res 46:39-47. 2011
    ....
  9. ncbi Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1beta production by human monocytes
    D A Tipton
    Department of Bioscience Research, College of Dentistry, The University of Tennessee Health Science Center, 62 South Dunlap Street, Memphis, TN 38163, USA
    Toxicol In Vitro 24:921-7. 2010
    ....
  10. ncbi Effect of cannabidiol on human gingival fibroblast extracellular matrix metabolism: MMP production and activity, and production of fibronectin and transforming growth factor ?
    S Y Rawal
    College of Dentistry Department of Periodontology Department of Bioscience Research College of Medicine Department of Molecular Sciences, The University of Tennessee Health Science Center, Memphis, TN, USA
    J Periodontal Res 47:320-9. 2012
    ..02). Conclusion:? The data suggest that the CBD may promote fibrotic gingival enlargement by increasing gingival fibroblast production of transforming growth factor?? and fibronectin, while decreasing MMP production and activity...

Research Grants1

  1. CELLULAR AND MOLECULAR TARGETING OF TMJ DESTRUCTION
    DAVID TIPTON; Fiscal Year: 2002
    ..It is hoped that completion of these three aims will provide a detailed knowledge of the biological basis of TMJ destruction via synovial fibroblasts and MMP pathway. ..