Research Topics
| S P TinlingSummaryAffiliation: University of California Country: USA Publications
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Publications
Gerbilline cholesteatoma development Part III. Increased proliferation index of basal keratinocytes of the tympanic membrane and external ear canalSteven P Tinling
Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of California Davis, Otolaryngology Research Laboratory, 1515 Newton Court, Davis, CA 95616, USA
Otolaryngol Head Neck Surg 135:116-23. 2006..To quantify the rate of basal cell division for keratinizing epithelium (KE) of the tympanic membrane (TM) and external ear canal (EAC) in spontaneous and induced gerbilline cholesteatomas...
Gerbilline cholesteatoma development. Part II: temporal histopathologic changes in the tympanic membrane and middle earSteven P Tinling
Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
Otolaryngol Head Neck Surg 134:953-60. 2006..Determine the sequence of gross and histopathologic change to the normal middle ear (ME), tympanic membrane (TM), and external auditory canal (EAC) during spontaneous gerbilline cholesteatoma development...
Gerbilline cholesteatoma development Part I: Epithelial migration pattern and rate on the gerbil tympanic membrane: comparisons with human and guinea pigSteven P Tinling
Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
Otolaryngol Head Neck Surg 134:788-93. 2006....
Microwave exposure increases bone demineralization rate independent of temperatureS P Tinling
Otolaryngology Research Laboratory, 1515 Newton Ct, Rm 209, Davis, CA 95616 4859, USA
J Microsc 215:230-5. 2004..Our results establish a positive effect of microwaves on the rate of bone demineralization which is independent of temperature...
Inhibition of post-meningitic cochlear injury with cerebrospinal fluid irrigationA H Yeung
Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA, USA
Otolaryngol Head Neck Surg 134:214-24. 2006..This study provides insight into some of the mechanisms responsible for post-meningitic hearing loss and labyrinthitis ossificans and presents a novel approach to reduce these complications...
Apical cochlear nerve exposed to perilymph in the gerbil and ratS P Tinling
Department of Otolaryngology, University of California, Davis, School of Medicine 95616
Hear Res 73:203-8. 1994....
Increased proliferation and migration of epithelium in advancing experimental cholesteatomasHyung-Jong Kim
Department of Otorhinolaryngology, College of Medicine, Hallym University, Anyang, Korea
Otol Neurotol 23:840-4. 2002..CONCLUSION: These results suggested that complex alterations of epidermal keratinocytes occur during cholesteatoma formation and that hyperproliferative and migratory processes play important roles in the pathogenesis of cholesteatoma...
Expression patterns of cytokeratins in cholesteatomas: evidence of increased migration and proliferationHyung Jong Kim
Department of Otolaryngology, College of Medicine, Hallym University, Chuncheon, Korea
J Korean Med Sci 17:381-8. 2002..The findings of this study support the basal cell hyperplasia hypotheses for the pathogenesis of aural cholesteatoma, with regard to hyperproliferation, migration, and an altered differentiation of keratinocytes...
The effects of superoxide dismutase in gerbils with bacterial meningitisNorman N Ge
Department of Otolaryngology-Head and Neck Surgery, University of California, Davis Medical Center, Davis, CA 98517, USA
Otolaryngol Head Neck Surg 131:563-72. 2004..753, P < 0.00001). CONCLUSIONS: IT injection of SOD significantly reduced cochlear fibrosis and neo-ossification, reduced the spiral ganglion cell loss, and decreased damage of the cochlear components following bacterial meningitis...
Role of tumor necrosis factor-alpha in sensorineural hearing loss after bacterial meningitisShervin Aminpour
Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
Otol Neurotol 26:602-9. 2005..Induction of meningitis with intrathecal tumor necrosis factor-alpha also resulted in hearing loss and cochlear injury similar to bacterial meningitis...
Nonhuman primate models of intrauterine cytomegalovirus infectionPeter A Barry
Department of Pathology and Laboratory Medicine, Center for Comparative Medicine, California National Primate Research Center, University of California, Davis, CA, USA
ILAR J 47:49-64. 2006....
Location and timing of initial osteoid deposition in postmeningitic labyrinthitis ossificans determined by multiple fluorescent labelsSteven P Tinling
Department of Otolaryngology, University of California, Davis, Davis, California, U.S.A
Laryngoscope 114:675-80. 2004..There was no apparent resorption of new bone and remodeling by 84 days after infection...
Fine structure histopathology of labyrinthitis ossificans in the gerbil modelSteven P Tinling
Department of Otolaryngology, University of California, Davis, School of Medicine, Davis, California, USA
Ann Otol Rhinol Laryngol 114:161-6. 2005..The destruction of the organ of Corti, spiral ganglion cells, stria vascularis, and cells of Reissner's membrane and the spiral ligament occurs even in the absence of ossification of the cochlear duct...
