Research Topics
| Aniko SzaboSummaryAffiliation: University of Utah Country: USA Publications
Research Grants
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Detail Information
Publications
Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assayLaurent Perreard
The ARUP Institute for Clinical and Experimental Pathology, SLC, Utah, USA
Breast Cancer Res 8:R23. 2006..The proliferation meta-gene offers an objective and quantitative measurement for grade and adds significant prognostic information to the biological subtypes...
A conscious mouse model of gastric ileus using clinically relevant endpointsMatthew A Firpo
Department of Surgery, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132, USA
BMC Gastroenterol 5:18. 2005....
Statistical modeling for selecting housekeeper genesAniko Szabo
Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT 84112, USA
Genome Biol 5:R59. 2004..We present appropriate models for selecting the best housekeepers to normalize quantitative data within a given tissue type (for example, breast cancer) and across different types of tissue samples...
Multivariate exploratory tools for microarray data analysisAniko Szabo
Huntsman Cancer Institute and Department of Oncological Sciences, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
Biostatistics 4:555-67. 2003..Different stopping rules associated with this procedure are evaluated. The usefulness of the proposed approach is illustrated with an application to the analysis of two sets of gene expression data...
Estimating an oncogenetic tree when false negatives and positives are presentAniko Szabo
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
Math Biosci 176:219-36. 2002..As an example we analyze a comparative genomic hybridization data set and show that addition of the error model significantly improves the ability of the model to describe the data...
Variable selection and pattern recognition with gene expression data generated by the microarray technologyA Szabo
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
Math Biosci 176:71-98. 2002....
Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissuesMichael Mullins
Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
Clin Chem 53:1273-9. 2007....
Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivoDavid E Joyner
SAR Lab, Sarcoma Services, Department of Orthopedics, Huntsman Cancer Institute and Primary Children's Medical Center, University of Utah, Salt Lake City, UT 84112, USA
J Cancer Res Clin Oncol 131:137-46. 2005..CONCLUSIONS: Linear discriminate analysis of cDNA gene expression profiles partitioned mesenchymal tumor classes, even when constrained by limited sample sizes...
Survival of men with clinically localized prostate cancer treated with prostatectomy, brachytherapy, or no definitive treatment: impact of age at diagnosisJonathan D Tward
Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah 84112, USA
Cancer 107:2392-400. 2006..The optimal treatment for men with early stage prostate cancer remains undefined. Survival of such patients after surgery, brachytherapy, or no definitive therapy was investigated specifically to determine the impact of age at diagnosis...
The risk of secondary malignancies over 30 years after the treatment of non-Hodgkin lymphomaJonathan D Tward
Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah 84112 5560, USA
Cancer 107:108-15. 2006..Survivors of non-Hodgkin lymphoma (NHL) are at increased risk for developing secondary malignancies. For the current study, the authors quantitated this risk in a group of NHL survivors over 30 years of follow-up...
Progressive disease in chronic lymphocytic leukemia is correlated with the DNA methylation indexMargaret K Yu
School of Medicine, Division of Hematology, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, USA
Leuk Res 31:773-7. 2007..Using Cox proportional hazard models for MI, adjusting for age and white blood cell count, only the DNA MI correlated with early clinical indications for systemic therapy (p=0.0038, HR=7.00, 95% CI: 1.90-26.20)...
Adjustments and measures of differential expression for microarray dataA Tsodikov
Huntsman Cancer Institute and Department of Oncological Sciences, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
Bioinformatics 18:251-60. 2002..We found that robust categorical adjustments outperform the ones based on a precisely defined stochastic model, including some commonly used procedures...
The risk of second primary malignancies up to three decades after the treatment of differentiated thyroid cancerAaron P Brown
Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, 1950 Circle of Hope, Salt Lake City, Utah 84112 5560, USA
J Clin Endocrinol Metab 93:504-15. 2008..The 10-yr survival rate of patients with differentiated thyroid cancer exceeds 90%. These patients may be at elevated risk for secondary cancers...
Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in head-and-neck cancer patientsYing J Hitchcock
Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, UT 84112, USA
Int J Radiat Oncol Biol Phys 73:779-88. 2009....
Identification of gene expression profiles that segregate patients with childhood leukemiaPhilip J Moos
Center for Children at the Huntsman Cancer Institute and Oncological Sciences, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Clin Cancer Res 8:3118-30. 2002....
Radiation therapy is associated with improved survival in patients with pancreatic adenocarcinoma: results of a study from the Surveillance, Epidemiology, and End Results (SEER) registry dataLisa Hazard
Huntsman Cancer Institute at the University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Cancer 110:2191-201. 2007..For the current study, the authors evaluated the effect of preoperative and postoperative radiation therapy on survival in patients with pancreatic adenocarcinoma...
Descriptive nomograms of adjuvant radiotherapy use and patterns of care analysis for stage I and II endometrial adenocarcinoma: A surveillance, epidemiology, and end results population studyChristopher M Lee
Department of Radiation Oncology, Huntsman Cancer Hospital and University of Utah Medical Center, Salt Lake City, Utah 99202, USA
Cancer 110:2092-100. 2007....
Gene expression profiling. Methods and clinical applications in oncologyE A Raetz
Department of Pediatrics, Division of Hematology-Oncology, Huntsman Cancer Institute, University of Utah School of Medicine, Primary Children's Medical Center, Salt Lake City, Utah, USA
Hematol Oncol Clin North Am 15:911-30, ix. 2001..This article discusses different genomic technologies, statistical methods for data analysis, and clinical applications of microarrays. Emphasis is devoted to integration of microarrays into the field of pediatric oncology...
Frequency and effect of adjuvant radiation therapy among women with stage I endometrial adenocarcinomaChristopher M Lee
Department of Radiation Oncology, Huntsman Cancer Hospital and University of Utah Medical Center, Salt Lake City 84112-5560, USA
JAMA 295:389-97. 2006..Future work is needed to continue to delineate clinical and biological factors, which can guide treatment decisions and account for disparities in outcome between varied subsets of patients...
Quantifying the role of PSA screening in the US prostate cancer mortality declineRuth Etzioni
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Causes Control 19:175-81. 2008..To quantify the plausible contribution of prostate-specific antigen (PSA) screening to the nearly 30% decline in the US prostate cancer mortality rate observed during the 1990s...
Research Grants
- Understanding racial differences in the natural history of prostate cancerAniko Szabo; Fiscal Year: 2007..abstract_text> ..
