Research Topics
Species | W SunSummaryAffiliation: University at Buffalo Country: USA Publications
Research Grants
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Detail Information
Publications
The China Productivity Project: results and conclusionsA T Steegmann
Department of Anthropology, SUNY Buffalo 14261, USA
Am J Phys Anthropol 103:295-313. 1997..6% of the work output variance. Simultaneous prediction by FASEM (LISREL) is also very strong...- Erratum to "changes in cutaneous sensory nerve fibers induced by skin-scratching in mice"Junichi Yamaoka
Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
J Dermatol Sci 47:172-82. 2007..Thus, it sometimes exacerbates the original lesions. However, the precise changes that develop in cutaneous sensory nerve fibers after skin-scratching have not yet been elucidated... - Noise exposure-induced enhancement of auditory cortex response and changes in gene expressionW Sun
Center for Hearing and Deafness, 137 Cary Hall, State University of New York at Buffalo, 3454 Main Street, Buffalo, NY 14214, USA
Neuroscience 156:374-80. 2008..These results suggest that noise exposure can induce a fast physiological change in the AC which may be related to the changes of HSP expressions... - Neonatal nicotine exposure impairs development of auditory temporal processingWei Sun
Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
Hear Res 245:58-64. 2008..These results suggest that neonatal nicotine exposure reduces gap-PPI implying an impairment of the normal development of auditory temporal processing by inducing changes in cholinergic systems... - Salicylate increases the gain of the central auditory systemW Sun
Center for Hearing and Deafness, 137 Cary Hall, State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214, USA
Neuroscience 159:325-34. 2009..The enhanced startle response may be the behavioral correlate of hyperacusis that often accompanies tinnitus and hearing loss... - Brain derived neurotrophic factor and neurotrophic factor 3 modulate neurotransmitter receptor expressions on developing spiral ganglion neuronsW Sun
Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, 137 Cary Hall, State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214, USA
Neuroscience 164:1854-66. 2009..These results indicate that NT-3 and BDNF exert a profound effect on the types of neurotransmitter receptors expressed on postnatal SGN, results that may have important implications for neural development and plasticity... - Substance P inhibits potassium and calcium currents in inner ear spiral ganglion neuronsWei Sun
Center for Hearing and Deafness, Hear Res Lab, SUNY University at Buffalo, 215 Parker Hall South Campus of UB, UB3435 Main Street, Buffalo, NY 14214, USA
Brain Res 1012:82-92. 2004..6% (n = 7); both currents recovered when SP was washed out. A SP antagonist blocked the SP-induced suppression of IK+ and ICa2+. These results indicate that SP acting through NK1 receptors can have direct neuromodulatory effects on SGNs... - Environmental noise affects auditory temporal processing development and NMDA-2B receptor expression in auditory cortexWei Sun
Center for Hearing and Deafness, The State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214, USA
Behav Brain Res 218:15-20. 2011..Thus, masking normal sound inputs with environmental noise during early life, but not adulthood, impairs temporal processing acuity as assessed with the gap detection threshold... - Early age conductive hearing loss causes audiogenic seizure and hyperacusis behaviorWei Sun
Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, The State University of New York at Buffalo, Buffalo, NY 14214, USA
Hear Res 282:178-83. 2011..These results indicate that early age conductive hearing loss can impair sound tolerance by reducing GABA inhibition in the IC, which may be related to hyperacusis seen in children with otitis media... - GABAergic neural activity involved in salicylate-induced auditory cortex gain enhancementJ Lu
Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 3435 Main Street, NY 14214, USA
Neuroscience 189:187-98. 2011..Collectively, these results suggest that the sound-evoked behavioral and neural hyperactivity induced by SS may arise from a SS-induced suppression of GABAergic inhibition in the AC... - Effect of inner and outer hair cell lesions on electrically evoked otoacoustic emissionsS Reyes
Hearing Research Lab, 215 Parker Hall, University of Buffalo, Buffalo, NY 14214, USA
Hear Res 158:139-50. 2001.... - Noise trauma impairs neurogenesis in the rat hippocampusK S Kraus
Center for Hearing and Deafness, 137 Cary Hall, University at Buffalo, Buffalo, NY 14214, USA
Neuroscience 167:1216-26. 2010..These results show for the first time that high intensity noise exposure not only damages the cochlea but also causes a significant and persistent decrease in hippocampal neurogenesis that may contribute to functional deficits in memory... - [Study on voltage-sensitive current of spiral ganglion cells in mice organ of Corti culture]W Sun
Hearing Research Lab of New York State University at Buffalo, Buffalo, New York 14214, USA
Zhonghua Er Bi Yan Hou Ke Za Zhi 36:178-82. 2001..To investigate the property of voltage-sensitive current in cochlear spiral ganglion cells of the C57BL/10J mice, an inbred strain which develops early onset hearing loss... - Relationship between noise-induced hearing-loss, persistent tinnitus and growth-associated protein-43 expression in the rat cochlear nucleus: does synaptic plasticity in ventral cochlear nucleus suppress tinnitus?K S Kraus
Center for Hearing and Deafness, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
Neuroscience 194:309-25. 2011..GAP-43 up-regulation most likely originates from medial olivocochlear neurons. Their increased excitatory input on inhibitory neurons in VCN may possibly reduce central hyperactivity and tinnitus... - Dopamine modulates sodium currents in cochlear spiral ganglion neuronsW Sun
Hearing Research Lab, SUNY University at Buffalo, NY 14214, USA
Neuroreport 12:803-7. 2001..The reduction of AP amplitude and voltage-gated Na+ current by DA and DA agonists provides a mechanism for suppressing spike activity in type I afferent neurons... - A novel behavioral paradigm for assessing tinnitus using schedule-induced polydipsia avoidance conditioning (SIP-AC)Edward Lobarinas
Center for Hearing and Deafness, Hearing Research Lab, University of Buffalo, 215 Parker Hall, Buffalo, NY 14214, USA
Hear Res 190:109-14. 2004..The ability to obtain sequential estimates of tinnitus-like behavior in an animal after administering a tinnitus-inducing agent could aid in understanding the underlying neural mechanisms and assessing potential treatments... - Salicylate induced tinnitus: behavioral measures and neural activity in auditory cortex of awake ratsGuang Yang
Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, University at Buffalo, Buffalo, NY 14214, USA
Hear Res 226:244-53. 2007..These preliminary physiology data suggest that salicylate induced tinnitus is associated with sound evoked hyperactivity in auditory cortex and spontaneous hypoactivity... - Electrically evoked otoacoustic emissions from the chicken earL Chen
Hearing Research Laboratories, 215 Parker Hall, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, South Campus, Buffalo, NY 14214, USA
Hear Res 161:54-64. 2001..These results suggest that the EEOAE has a biological origin in the cochlea, which could presumably involve electrically evoked stereocilia bundle movements... - Changes in NMDA receptor expression in auditory cortex after learningWei Sun
Center for Hearing and Deafness, University at Buffalo, SUNY, Buffalo, NY, USA
Neurosci Lett 374:63-8. 2005..These results suggest that changes in NMDA receptors 2A and 2B and Arc enhance synaptic plasticity, thereby facilitating experience-dependent cortical remodeling and auditory learning... - Chronic and acute effects of dronedarone on the action potential of rabbit atrial muscle preparations: comparison with amiodaroneWei Sun
Cardiovascular Research Laboratory, Department of Cardiology, VA Greater Los Angeles Health Care System of West Los Angeles, and UCLA School of Medicine, 90073, USA
J Cardiovasc Pharmacol 39:677-84. 2002..05; 182 +/- 11 V/s amiodarone, p < 0.05). Thus, chronic and acute electrophysiologic effects of dronedarone on rabbit atrial muscle are similar to those of amiodarone, suggesting a similar potential against atrial arrhythmias... - Azimilide inhibits multiple cardiac potassium currents in human atrial myocytesFuhua Chen
Department of Pediatrics, University of California at Los Angeles, School of Medicine, Los Angeles, CA 90095, USA
J Cardiovasc Pharmacol Ther 7:255-64. 2002.... - Changes in cutaneous sensory nerve fibers induced by skin-scratching in miceJunichi Yamaoka
Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
J Dermatol Sci 46:41-51. 2007..Thus, it sometimes exacerbates the original lesions. However, the precise changes that develop in cutaneous sensory nerve fibers after skin-scratching have not yet been elucidated... - Effects of nimodipine, an L-type calcium channel antagonist, on the chicken's cochlear potentialsLin Chen
Auditory Research Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China
Hear Res 221:82-90. 2006..These results suggest that L-type calcium channels control neurotransmitter release from avian hair cells...
Research Grants
- Mechanisms of auditory cortex development and role of NMDA receptorsWei Sun; Fiscal Year: 2007..The result of these studies may lead to new insights into pharmacologic therapies for improving auditory memory and learning deficits in children, aphasia patients and cochlear implant users. ..