W J Streit

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Microglia and macrophages in the developing CNS
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville 32611, USA
    Neurotoxicology 22:619-24. 2001
  2. ncbi Reactive microgliosis
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32610, USA
    Prog Neurobiol 57:563-81. 1999
  3. ncbi Chemokines and Alzheimer's disease
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL 32611, USA
    Neurobiol Aging 22:909-13. 2001
  4. ncbi Microglial response to brain injury: a brief synopsis
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32610 0244, USA
    Toxicol Pathol 28:28-30. 2000
  5. ncbi Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32611, Florida, USA
    J Neurosci Res 61:10-20. 2000
  6. ncbi Exposure to in utero irradiation produces disruption of radial glia in rats
    S N Roper
    Department of Neurological Surgery, University of Florida and Gainesville VA Medical Center, 32610 0265, USA
    Dev Neurosci 19:521-8. 1997
  7. ncbi Interleukin-2 gene deletion produces a robust reduction in susceptibility to experimental autoimmune encephalomyelitis in C57BL/6 mice
    J M Petitto
    Department of Psychiatry, UF Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610 0256, USA
    Neurosci Lett 285:66-70. 2000
  8. ncbi Induction of manganese superoxide dismutase in acute spinal cord injury
    J N Earnhardt
    Department of Neuroscience, University of Florida College of Medicine, Evelyn F. and William L. McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, USA
    J Neurotrauma 19:1065-79. 2002
  9. ncbi Characterization of the chicken GCAP gene array and analyses of GCAP1, GCAP2, and GC1 gene expression in normal and rd chicken pineal
    S L Semple-Rowland
    University of Florida Brain Institute, Department of Neuroscience, Gainesville, FL 32610, USA
    Mol Vis 5:14. 1999
  10. ncbi Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    J K Harrison
    Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL 32610, USA
    Proc Natl Acad Sci U S A 95:10896-901. 1998

Collaborators

Detail Information

Publications11

  1. ncbi Microglia and macrophages in the developing CNS
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville 32611, USA
    Neurotoxicology 22:619-24. 2001
    ..The study of reactive microgliosis may prove useful in the histopathological analysis of neurotoxicant-induced brain damage during development...
  2. ncbi Reactive microgliosis
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32610, USA
    Prog Neurobiol 57:563-81. 1999
    ....
  3. ncbi Chemokines and Alzheimer's disease
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL 32611, USA
    Neurobiol Aging 22:909-13. 2001
    ..Understanding neuron-microglia interactions is essential for understanding AD pathogenesis, and disturbances in chemokine-mediated intercellular communication may contribute toward a generalized impairment of microglial cell function...
  4. ncbi Microglial response to brain injury: a brief synopsis
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32610 0244, USA
    Toxicol Pathol 28:28-30. 2000
    ..Reactive microgliosis should be viewed as a cellular effort to initiate ameliorative and reparative measures in the injured brain...
  5. ncbi Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32611, Florida, USA
    J Neurosci Res 61:10-20. 2000
    ....
  6. ncbi Exposure to in utero irradiation produces disruption of radial glia in rats
    S N Roper
    Department of Neurological Surgery, University of Florida and Gainesville VA Medical Center, 32610 0265, USA
    Dev Neurosci 19:521-8. 1997
    ..This suggests that disruption of radial glial fibers by gamma-irradiation is a major factor in the pathogenesis of cortical dysgenesis in this model...
  7. ncbi Interleukin-2 gene deletion produces a robust reduction in susceptibility to experimental autoimmune encephalomyelitis in C57BL/6 mice
    J M Petitto
    Department of Psychiatry, UF Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610 0256, USA
    Neurosci Lett 285:66-70. 2000
    ..These data demonstrate that vulnerability to EAE is markedly reduced in C57BL/6 mice lacking IL-2, and suggest that this cytokine may play a critical role in autoimmune processes of the central nervous system...
  8. ncbi Induction of manganese superoxide dismutase in acute spinal cord injury
    J N Earnhardt
    Department of Neuroscience, University of Florida College of Medicine, Evelyn F. and William L. McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, USA
    J Neurotrauma 19:1065-79. 2002
    ..In summary, these results demonstrate that this potent cytoprotective antioxidant enzyme is rapidly and significantly induced as a consequence of SCI...
  9. ncbi Characterization of the chicken GCAP gene array and analyses of GCAP1, GCAP2, and GC1 gene expression in normal and rd chicken pineal
    S L Semple-Rowland
    University of Florida Brain Institute, Department of Neuroscience, Gainesville, FL 32610, USA
    Mol Vis 5:14. 1999
    ....
  10. ncbi Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    J K Harrison
    Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL 32610, USA
    Proc Natl Acad Sci U S A 95:10896-901. 1998
    ..These data describe mechanisms of cellular communication between neurons and microglia, involving fractalkine and CX3CR1, which occur in both normal and pathological states of the central nervous system...
  11. ncbi Down-regulation of the macrophage lineage through interaction with OX2 (CD200)
    R M Hoek
    DNAX Research Institute of Molecular and Cellular Biology, 901 California Avenue, Palo Alto, CA 94304, USA
    Science 290:1768-71. 2000
    ..Thus, in diverse tissues OX2 delivers an inhibitory signal for the macrophage lineage...