Research Topics
| Paul T SpellmanSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Design and implementation of microarray gene expression markup language (MAGE-ML)Paul T Spellman
Department of Cell and Molecular Biology, University of California at Berkeley, Berkeley, CA 94720 3206, USA
Genome Biol 3:RESEARCH0046. 2002..Only when data can be easily exchanged will the entire biological community be able to derive the full benefit from such microarray studies...
Final words: cell age and cell cycle are unlinkedPaul T Spellman
Lawrence Berkeley National Laboratory, Life Science Division, 1 Cyclotron Road, Building 84, Room 336, Berkeley, California 94720, USA
Trends Biotechnol 22:277-8. 2004..Unfortunately the corollaries of this law are rather suspect, drawing inferences from cell age to cell size to the cell cycle...
Reply: whole-culture synchronization - effective tools for cell cycle studiesPaul T Spellman
Lawrence Berkeley National Laboratory, Life Science Division, 1 Cyclotron Road, Building 84, Room 336, Berkeley, California 94720, USA
Trends Biotechnol 22:270-3. 2004....
GenomeGraphs: integrated genomic data visualization with RSteffen Durinck
Life Sciences Department, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA 94720, USA
BMC Bioinformatics 10:2. 2009..In addition, genomic data analysis requires integrated visualization of experimental data along with constantly changing genomic annotation and statistical analyses...
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesRichard M Neve
Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94270, USA
Cancer Cell 10:515-27. 2006..We show, using Trastuzumab (Herceptin) monotherapy as an example, that the system can be used to identify molecular features that predict or indicate response to targeted therapies or other physiological perturbations...
The Toll and Imd pathways are the major regulators of the immune response in DrosophilaEnnio De Gregorio
, CNRS, F-91198 Gif-sur-Yvette, France
EMBO J 21:2568-79. 2002..Interestingly, we observed that some Drosophila immune-responsive genes are located in gene clusters, which often are transcriptionally co-regulated...
A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TABTim F Rayner
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
BMC Bioinformatics 7:489. 2006..However, the complexity of the MAGE-ML format has made its use impractical for laboratories lacking dedicated bioinformatics support...
Genomic and transcriptional aberrations linked to breast cancer pathophysiologiesKoei Chin
Comprehensive Cancer Center, 2340 Sutter Street, University of California, San Francisco, San Francisco, California 94143
Cancer Cell 10:529-41. 2006..Nine of these (FGFR1, IKBKB, ERBB2, PROCC, ADAM9, FNTA, ACACA, PNMT, and NR1D1) are considered druggable. Low-level CNAs appear to contribute to cancer progression by altering RNA and cellular metabolism...
Amplification of 11q13 in ovarian carcinomaLindsay A Brown
Department of Pathology, Vancouver Coastal Health Research Institute, Genetic Pathology Evaluation Centre, British Columbia Cancer Agency, University of British Columbia, Vancouver, BC, Canada
Genes Chromosomes Cancer 47:481-9. 2008..This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
