JANE M SOTTILE

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions
    Jane Sottile
    Department of Medicine, Center for Cardiovascular Research, Rochester, New York 14642, USA
    Mol Biol Cell 13:3546-59. 2002
  2. ncbi Regulation of angiogenesis by extracellular matrix
    Jane Sottile
    Center for Cardiovascular Research, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 679, Rochester, NY 14642, USA
    Biochim Biophys Acta 1654:13-22. 2004
  3. ncbi Fibronectin matrix turnover occurs through a caveolin-1-dependent process
    Jane Sottile
    Center for Cardiovascular Research, Department of Medicine, University of Rochester, Rochester, NY 14642, USA
    Mol Biol Cell 16:757-68. 2005
  4. ncbi Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin
    Jane Sottile
    Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 293:C1934-46. 2007
  5. ncbi The incorporation of fibrinogen into extracellular matrix is dependent on active assembly of a fibronectin matrix
    Marian Pereira
    Department of Medicine-Vascular Medicine Unit, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Cell Sci 115:609-17. 2002
  6. ncbi Collagen I matrix turnover is regulated by fibronectin polymerization
    Feng Shi
    Aab Cardiovascular Research Institute, Univ of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 298:C1265-75. 2010
  7. ncbi Fibronectin is an important regulator of flow-induced vascular remodeling
    Hou Yu Chiang
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 29:1074-9. 2009

Research Grants

  1. MECHANISMS REGULATING FIBRONECTIN DEPOSITION
    Jane Sottile; Fiscal Year: 2003
  2. Fibronectin in Cell Growth and Vascular Remodeling
    Jane Sottile; Fiscal Year: 2007
  3. Mechanisms and Effects of Fibronectin Matrix Remodeling
    Jane Sottile; Fiscal Year: 2007

Collaborators

Detail Information

Publications7

  1. ncbi Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions
    Jane Sottile
    Department of Medicine, Center for Cardiovascular Research, Rochester, New York 14642, USA
    Mol Biol Cell 13:3546-59. 2002
    ....
  2. ncbi Regulation of angiogenesis by extracellular matrix
    Jane Sottile
    Center for Cardiovascular Research, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 679, Rochester, NY 14642, USA
    Biochim Biophys Acta 1654:13-22. 2004
    ..Hence, extracellular matrix molecules and extracellular matrix remodelling events play a key role in regulating angiogenesis...
  3. ncbi Fibronectin matrix turnover occurs through a caveolin-1-dependent process
    Jane Sottile
    Center for Cardiovascular Research, Department of Medicine, University of Rochester, Rochester, NY 14642, USA
    Mol Biol Cell 16:757-68. 2005
    ..These data show that fibronectin matrix turnover occurs through a caveolin-1-dependent process. Caveolin-1 regulation of fibronectin matrix turnover is a novel mechanism regulating extracellular matrix remodeling...
  4. ncbi Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin
    Jane Sottile
    Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 293:C1934-46. 2007
    ....
  5. ncbi The incorporation of fibrinogen into extracellular matrix is dependent on active assembly of a fibronectin matrix
    Marian Pereira
    Department of Medicine-Vascular Medicine Unit, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Cell Sci 115:609-17. 2002
    ..From these data, we hypothesize that fibrinogen deposition rapidly changes the topology of the extracellular matrix to provide a surface for cell migration and matrix remodeling during tissue repair...
  6. ncbi Collagen I matrix turnover is regulated by fibronectin polymerization
    Feng Shi
    Aab Cardiovascular Research Institute, Univ of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 298:C1265-75. 2010
    ..These data highlight the complexity of ECM remodeling. This multifaceted regulatory process may be important to ensure tight regulation of ECM fibronectin and collagen I levels...
  7. ncbi Fibronectin is an important regulator of flow-induced vascular remodeling
    Hou Yu Chiang
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 29:1074-9. 2009
    ....

Research Grants9

  1. MECHANISMS REGULATING FIBRONECTIN DEPOSITION
    Jane Sottile; Fiscal Year: 2003
    ....
  2. Fibronectin in Cell Growth and Vascular Remodeling
    Jane Sottile; Fiscal Year: 2007
    ..These studies will provide important insights into the complex interplay between smooth muscle cells and extracellular matrix, which plays a critical role in the development and progression of vascular disease. ..
  3. Mechanisms and Effects of Fibronectin Matrix Remodeling
    Jane Sottile; Fiscal Year: 2007
    ....