Research Topics
| David L SmithSummaryAffiliation: University of Florida Country: USA Publications
| Collaborators
|
Detail Information
Publications
Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteriaDavid L Smith
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 99:6434-9. 2002..Our model indicates that the greatest impact occurs very early in the emergence of resistance, when AR bacteria are rare, possibly below the detection limits of current surveillance methods...
Modelling the global constraints of temperature on transmission of Plasmodium falciparum and P. vivaxPeter W Gething
Spatial Ecology and Epidemiology Group, Department of Zoology, University of Oxford, Oxford, UK
Parasit Vectors 4:92. 2011....
A framework for assessing the feasibility of malaria eliminationBruno Moonen
Clinton Health Access Initiative, Boston, USA
Malar J 9:322. 2010....
How absolute is zero? An evaluation of historical and current definitions of malaria eliminationJustin M Cohen
Clinton Health Access Initiative, Boston MA 02127, USA
Malar J 9:213. 2010..Finally, guidelines are discussed for deriving the separate operational definitions and metrics that will be required to make these concepts relevant, measurable, and achievable for a particular environment...
Clinically immune hosts as a refuge for drug-sensitive malaria parasitesEili Y Klein
Resources for the Future, 1616 P St, NW, Washington, DC 20036, USA
Malar J 7:67. 2008..This model reconsiders the role of immunity in the dynamics of malaria transmission and its impact on the evolution of antimalarial drug resistance under the assumption that immune individuals are infectious...
Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populationsSaranath Lawpoolsri
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
Malar J 8:159. 2009....
Standardizing estimates of the Plasmodium falciparum parasite rateDavid L Smith
Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
Malar J 6:131. 2007..This confounds simple comparisons of PfPR surveys conducted at different times or places...
Prospective strategies to delay the evolution of anti-malarial drug resistance: weighing the uncertaintyDavid L Smith
Emerging Pathogens Institute and Department of Biology, University of Florida, Gainesville, 32611, USA
Malar J 9:217. 2010..Such strategies are deployed to best effect before resistance has emerged, under conditions of great uncertainty...
Gametocytemia in Plasmodium vivax and Plasmodium falciparum infectionsF Ellis McKenzie
Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Parasitol 92:1281-5. 2006..falciparum patients with gametocytemia had similar platelet counts but lower red blood cell counts, hemoglobin levels, hematocrit levels, and higher lymphocyte counts than patients without gametocytemia...
Endemicity response timelines for Plasmodium falciparum eliminationDavid L Smith
Department of Zoology and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA
Malar J 8:87. 2009..The scaling up of malaria control and renewed calls for malaria eradication have raised interest in defining timelines for changes in malaria endemicity...
Predicting changing malaria risk after expanded insecticide-treated net coverage in AfricaDavid L Smith
Department of Biology and Emerging Pathogens Institute, University of Florida, P O Box 100009, Gainesville, Florida 32610, USA
Trends Parasitol 25:511-6. 2009..This theory provides a method for context-dependent evaluation of ITN programs and a basis for setting rational ITN coverage targets over the next decade...
Ranking of elimination feasibility between malaria-endemic countriesAndrew J Tatem
Department of Geography, University of Florida, Gainesville, FL 32610, USA edu
Lancet 376:1579-91. 2010....
Strain theory of malaria: the first 50 yearsF Ellis McKenzie
Fogarty International Center, Building 16, National Institutes of Health, Bethesda, Maryland 20892, USA
Adv Parasitol 66:1-46. 2008..Here we review the search for a definition of 'strain', suggest how the data and discussion shaped current understandings of many aspects of malaria and sketch a number of specific connections with perspectives from the past 30 years...
Revisiting the basic reproductive number for malaria and its implications for malaria controlDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS Biol 5:e42. 2007..Therefore, strategic planning for malaria control should consider R0, the spatial scale of transmission, human population density, and heterogeneous biting...
The unexpected importance of mosquito oviposition behaviour for malaria: non-productive larval habitats can be sources for malaria transmissionArnaud Le Menach
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Malar J 4:23. 2005..One of the possible strategies of malaria control is to identify local vector species and then attack water bodies that contain their larvae...
Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malariaWendy Prudhomme O'Meara
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS Med 3:e141. 2006....
Synchrony, waves, and spatial hierarchies in the spread of influenzaCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Science 312:447-51. 2006..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints...
Progress in modelling malaria transmissionDavid L Smith
Department of Zoology and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA
Adv Exp Med Biol 673:1-12. 2010..The future of malaria modeling will involve applying these models to make decisions about real systems and finding new ways to test the underlying causes of the patterns...
The use of mobile phone data for the estimation of the travel patterns and imported Plasmodium falciparum rates among Zanzibar residentsAndrew J Tatem
Department of Geography, 3141 Turlington Hall, University of Florida, Gainesville, Florida 32611 7315, USA
Malar J 8:287. 2009....
Fever in patients with mixed-species malariaF Ellis McKenzie
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Clin Infect Dis 42:1713-8. 2006..Clinical symptoms of mixed-species malaria infections have been variously reported as both less severe and more severe than those of single-species infections...
Estimating the reproductive numbers for the 2008-2009 cholera outbreaks in ZimbabweZindoga Mukandavire
Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA
Proc Natl Acad Sci U S A 108:8767-72. 2011....
International population movements and regional Plasmodium falciparum malaria elimination strategiesAndrew J Tatem
Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA
Proc Natl Acad Sci U S A 107:12222-7. 2010..For more isolated countries, a nationally focused control or elimination program is likely to stand a better chance of success than those receiving high levels of visitors and migrants from high-transmission regions...
Strategic interactions in multi-institutional epidemics of antibiotic resistanceDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 2220, USA
Proc Natl Acad Sci U S A 102:3153-8. 2005..We conclude that regional coordination and planning for HIC is an essential element of public health planning for hospital-acquired infections...
The risk of a mosquito-borne infection in a heterogeneous environmentDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS Biol 2:e368. 2004..Finally, we show that estimates for the average risk of infection that are based on the average entomological inoculation rate are strongly biased in heterogeneous environments...
A quantitative analysis of transmission efficiency versus intensity for malariaDavid L Smith
1 Emerging Pathogens Institute, University of Florida, Gainesville, Florida 32610, USA 2 Department of Biology, University of Florida, Gainesville, Florida 32611, USA
Nat Commun 1:108. 2010....
The complete management of extremity vascular injury in a local population: a wartime report from the 332nd Expeditionary Medical Group/Air Force Theater Hospital, Balad Air Base, IraqMichael A Peck
332nd Air Force Theater Hospital AFTH, Balad, Iraq, and Norman M Rich Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
J Vasc Surg 45:1197-204; discussion 1204-5. 2007..This study reports the complete management of extremity vascular injury in a local wartime population and illustrates the unique aspects of this cohort and management strategy...
Statics and dynamics of malaria infection in Anopheles mosquitoesDavid L Smith
Building 16, Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Malar J 3:13. 2004..The classic formulae are used to to illustrate how malaria control reduces malaria transmission and show that increased mosquito mortality has an effect even larger than was proposed by Macdonald in the 1950's...
Geographical distribution and risk factors associated with enteric diseases in VietnamLouise A Kelly-Hope
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Trop Med Hyg 76:706-12. 2007..The distinct geographical patterns of each disease appear to be driven by a combination of different ecological factors...
Agricultural antibiotics and human healthDavid L Smith
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
PLoS Med 2:e232. 2005
A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDaShannon L Takala
Center for Vaccine Development, University of Maryland School of Medicine, HSF1 480, Baltimore, Maryland 21201, USA
Malar J 5:31. 2006..Methods are needed to monitor genetic diversity in polymorphic vaccine antigens, but determining which genetic variants of such antigens are present in infected individuals is complicated by the frequent occurrence of mixed infections...
An elaborated feeding cycle model for reductions in vectorial capacity of night-biting mosquitoes by insecticide-treated netsArnaud Le Menach
Universite Pierre et Marie Curie Paris 6, UMR S 707, Paris, France
Malar J 6:10. 2007..Insecticide Treated Nets (ITNs) are an important tool for malaria control. ITNs are effective because they work on several parts of the mosquito feeding cycle, including both adult killing and repelling effects...
Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in MaliShannon L Takala
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
PLoS Med 4:e93. 2007....
Short report: rare Plasmodium falciparum merozoite surface protein 1 19-kda (msp-1(19)) haplotypes identified in Mali using high-throughput genotyping methodsShannon L Takala
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
Am J Trop Med Hyg 76:855-9. 2007....
Coupling ecology and evolution: malaria and the S-gene across time scalesZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907 1395, USA
Math Biosci 189:1-19. 2004..We analyze the slow time scale dynamics to investigate the impact of malaria on the evolution of resistance...
