Duane A Sewell

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV-16 transformed tumors
    Duane A Sewell
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, United States
    Vaccine 26:5315-20. 2008
  2. ncbi Listeria-based vaccines can overcome tolerance by expanding low avidity CD8+ T cells capable of eradicating a solid tumor in a transgenic mouse model of cancer
    Nicholas C Souders
    Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Immun 7:2. 2007
  3. ncbi Regression of HPV-positive tumors treated with a new Listeria monocytogenes vaccine
    Duane A Sewell
    Department of Otorhinolaryngology, University of Pennsylvania School of Medicine, Philadelphia, USA
    Arch Otolaryngol Head Neck Surg 130:92-7. 2004
  4. ncbi Effect of a novel DNA vaccine on angiogenesis and tumor growth in vivo
    Kibwei A McKinney
    Department of Otorhinolaryngology, University of Pennsylvania School of Medicine, Philadelphia, USA
    Arch Otolaryngol Head Neck Surg 136:859-64. 2010
  5. ncbi Proteomic signatures in laryngeal squamous cell carcinoma
    Duane A Sewell
    Department of Otorhinolaryngology, Tumor Virology Program of the Abramson Comprehensive Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 69:77-84. 2007
  6. ncbi Diffuse intranasal papillomatosis and its association with human papillomavirus
    Benjamin S Bleier
    Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Arch Otolaryngol Head Neck Surg 134:778-80. 2008
  7. ncbi Synthetic peptide-based cancer vaccines: lessons learned and hurdles to overcome
    Caroline J Voskens
    Department of Pathology, University of Maryland, 16 South Eutaw Street, Suite 500, Baltimore, MD 21201 168, USA
    Curr Mol Med 9:683-93. 2009

Collaborators

Detail Information

Publications7

  1. ncbi Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV-16 transformed tumors
    Duane A Sewell
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, United States
    Vaccine 26:5315-20. 2008
    ..This study shows that Listeria-based vaccines are able to slow autochthonous tumor growth and break immunological tolerance...
  2. ncbi Listeria-based vaccines can overcome tolerance by expanding low avidity CD8+ T cells capable of eradicating a solid tumor in a transgenic mouse model of cancer
    Nicholas C Souders
    Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Immun 7:2. 2007
    ..In this model, Listeria-based vaccines against E7 appear to be overcoming central tolerance by expanding low avidity CD8+ T cells specific for E7 that are not deleted during thymopoesis and can eliminate solid tumors...
  3. ncbi Regression of HPV-positive tumors treated with a new Listeria monocytogenes vaccine
    Duane A Sewell
    Department of Otorhinolaryngology, University of Pennsylvania School of Medicine, Philadelphia, USA
    Arch Otolaryngol Head Neck Surg 130:92-7. 2004
    ..Because of its unique ability to induce a cellular immune response, the intracellular bacteria Listeria monocytogenes has been studied as a potential HPV-positive tumor vaccine...
  4. ncbi Effect of a novel DNA vaccine on angiogenesis and tumor growth in vivo
    Kibwei A McKinney
    Department of Otorhinolaryngology, University of Pennsylvania School of Medicine, Philadelphia, USA
    Arch Otolaryngol Head Neck Surg 136:859-64. 2010
    ..To develop a DNA cancer vaccine that targets the vascular endothelial growth factor receptor...
  5. ncbi Proteomic signatures in laryngeal squamous cell carcinoma
    Duane A Sewell
    Department of Otorhinolaryngology, Tumor Virology Program of the Abramson Comprehensive Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 69:77-84. 2007
    ..With these findings, we have identified potential biomarkers which may contribute to the pathogenesis of laryngeal carcinoma, and which may be suitable as targets for novel therapeutic and/or diagnostic modalities...
  6. ncbi Diffuse intranasal papillomatosis and its association with human papillomavirus
    Benjamin S Bleier
    Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Arch Otolaryngol Head Neck Surg 134:778-80. 2008
  7. ncbi Synthetic peptide-based cancer vaccines: lessons learned and hurdles to overcome
    Caroline J Voskens
    Department of Pathology, University of Maryland, 16 South Eutaw Street, Suite 500, Baltimore, MD 21201 168, USA
    Curr Mol Med 9:683-93. 2009
    ....