Research Topics
| Laligam N SekharSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Cerebral revascularization for ischemia, aneurysms, and cranial base tumorsLaligam N Sekhar
Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
Neurosurgery 62:1373-408; discussion 1408-10. 2008..Current operative techniques are illustrated with drawings and video clips...
Microsurgical management of anterior communicating artery aneurysmsLaligam N Sekhar
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
Neurosurgery 61:273-90: discussion 290-2. 2007....
The use of fibrin glue to stop venous bleeding in the epidural space, vertebral venous plexus, and anterior cavernous sinus: technical noteLaligam N Sekhar
Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
Neurosurgery 61:E51; discussion E51. 2007..Various techniques have been used to stop venous bleeding from the epidural space, vertebral venous plexus, and cavernous sinus. Here, we describe our experience with the use of fibrin glue to stop venous bleeding in these areas...
Neuroendovascular management of tumors and vascular malformations of the head and neckLaligam N Sekhar
Department of Neurosurgery, Harborview Medical Center, University of Washington, 325 9th Avenue, Box 359766, Seattle, WA 98105 9950, USA
Neurosurg Clin N Am 20:453-85. 2009..An interdisciplinary approach and treatment in high-volume centers are vital to obtain maximal benefit for patients...
Multimodality treatment of intracranial dural arteriovenous fistulas in the Onyx era: a single center experienceSabareesh K Natarajan
Department of Neurological Surgery, Harborview Medical Center, University of Washington, Seattle, Washington, USA
World Neurosurg 73:365-79. 2010..An algorithm is presented for treatment of DAVFs with Onyx, and the role of endovascular transvenous, surgical, and radiosurgical approaches are presented...
Intracranial in situ side-to-side microvascular anastomosis: principles, operative technique, and applicationsDinesh Ramanathan
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
World Neurosurg 73:317-25. 2010..This technique is used for microsurgical clipping of aneurysms, when indicated. It is important to study the angiographic results, both immediate and long term, along with the clinical outcomes and indications of the procedure...
Multimodality treatment of brain arteriovenous malformations with microsurgery after embolization with onyx: single-center experience and technical nuancesSabareesh K Natarajan
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
Neurosurgery 62:1213-25; discussion 1225-6. 2008..To report our experience with the treatment of brain arteriovenous malformations (AVM) with microsurgical resection after embolization with Onyx liquid embolic agent (eV3, Irvine, CA)...
High-flow bypass grafts in the management of complex intracranial aneurysmsAlex A Mohit
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
Neurosurgery 60:ONS105-22; discussion ONS122-3. 2007..Seven intraoperative videos have been provided to demonstrate the various techniques of radial artery graft harvesting, cervical exposure of carotid vessels, bypasses, and concurrent aneurysm management...
Current comprehensive management of cranial base chordomas: 10-year meta-analysis of observational studiesSalvatore Di Maio
Department of Neurological Surgery, University of Washington, Harborview Medical Center, Seattle, Washington
J Neurosurg 115:1094-105. 2011..Adjuvant proton-beam, carbon ion, and modern fractionated photon radiation therapy techniques offered a similar rate of PFS and OS at 5 years...
Endovascular procedures with CTA and MRA roadmappingMichael R Levitt
Department of Neurological Surgery, University of Washington, Seattle, WA, USA
J Neuroimaging 21:259-62. 2011..The ability to use these studies during invasive neuroangiographic procedures reduces additional contrast and radiation exposure, and allows for the integration of extravascular imaging...
Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chordomasFortios Tzortzidis
Department of Neurosurgery, University of Washington, Seattle, Washington, USA
Neurosurgery 59:230-7; discussion 230-7. 2006..A more conservative strategy is recommended in reoperation cases, especially after previous radiotherapy, to reduce postoperative complications...
Treatment of coil embolization failed recurrent giant basilar tip aneurysms with bypass and surgical occlusionDinesh Ramanathan
Department of Neurosurgery, University of Washington, Seattle, Washington 98104, USA
J Neurointerv Surg 2:237-41. 2010..Surgical treatment with a bypass to the PCA, with clipping of the aneurysm or proximal ligation of the basilar artery can be an effective treatment option for giant basilar tip aneurysms...
"Stent view" flat-detector CT and stent-assisted treatment strategies for complex intracranial aneurysmsMichael R Levitt
Department of Neurological Surgery, University of Washington Medical Center and Harborview Medical Center, Seattle, Washington, USA
World Neurosurg 75:275-8. 2011..Intracranial stents are difficult to visualize with conventional computed tomography (CT) or fluoroscopy. "Stent view" flat-detector CT can be used to visualize intracranial stents during endovascular treatment...
Large distal anterior cerebral artery aneurysm treated with resection and interposition graft: case reportMikhail Gelfenbeyn
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
Neurosurgery 64:E1008-9; discussion E1009. 2009..The report presents an unusual case of a complex DACA aneurysm managed by resection and interposition arterial graft...
Petroclival meningiomas: multimodality treatment and outcomes at long-term follow-upSabareesh K Natarajan
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
Neurosurgery 60:965-79; discussion 979-81. 2007..To evaluate patients' clinical outcome, survival, and performance status, at the long-term follow-up evaluation after aggressive microsurgical resection of petroclival meningiomas...
Bypass grafting and revascularization in the management of posterior circulation aneurysmsJames J Evans
Department of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
Neurosurgery 55:1036-49. 2004..Bypass procedures remain an important method of management of complex posterior circulation aneurysms, in addition to endovascular procedures...
Trapped fourth ventricle phenomenon following aneurysm rupture of the posterior circulation: case reportsManuel Ferreira
Department of Neurosurgery, University of Washington Medical School, Seattle, Washington, USA
Neurosurgery 70:E253-8; discussion E258. 2012..We describe the first adult case series of individuals who developed delayed isolated fourth ventricles after rupture of intracranial posterior circulation aneurysms and define treatment modality...
Synchronous chronic middle cerebral artery occlusion and ipsilateral dural arteriovenous fistulaDaniel L Cooke
Department of Radiology, Harborview Medical Center, University of Washington, Seattle, WA 98195, USA
Clin Nucl Med 36:570-3. 2011..This case supports the hypothesis that dAVFs may arise secondary to angiogenic growth factors related to regional tissue hypoxia...
Histopathological changes in brain arteriovenous malformations after embolization using Onyx or N-butyl cyanoacrylate. Laboratory investigationSabareesh Kumar Natarajan
Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA
J Neurosurg 111:105-13. 2009....
Multiportal endoscopic approaches to the central skull base: a cadaveric studyJeremy N Ciporen
Department of Neurological Surgery, The University of Washington School of Medicine, Seattle, Washington, USA
World Neurosurg 73:705-12. 2010....
Incidence of cerebrospinal fluid leak following petrosectomy and analysis of avoidance techniquesBrian P Walcott
Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Neurosci 19:92-4. 2012..CSF diversion and vascularized temporalis muscle flaps are effective in preventing the development of postoperative CSF leaks following petrosectomy...
Reconstruction options for complex middle cerebral artery aneurysmsLaligam N Sekhar
Department of Neurosurgery, North Shore University Hospital, Great Neck, New York 11021, USA
Neurosurgery 56:66-74; discussion 66-74. 2005..To describe techniques of reconstruction for unclippable and uncoilable middle cerebral artery aneurysms...
Intradural cranial chordoma: a rare presentation of an uncommon tumor. Surgical experience and review of the literatureFabio Roberti
Department of Neurosurgery, George Washington University Medical Center, Washington, DC 20037, USA
J Neurosurg 106:270-4. 2007..They present an illustrative surgical scenario and discuss the published literature, pathogenesis, and histopathological features as well as available follow-up data on the clinical behavior of these intradural lesions...
Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chondrosarcomasFotios Tzortzidis
Department of Neurosurgery, University of Washington, Seattle, Washington 98104, USA
Neurosurgery 58:1090-8; discussion 1090-8. 2006..The study cannot comment about the efficacy of radiotherapy. Approximately half of the patients survived without recurrence at long-term follow-up (>132 mo). The functional status of the surviving patients was excellent at follow-up...
Intraventricular tissue plasminogen activator for the prevention of vasospasm and hydrocephalus after aneurysmal subarachnoid hemorrhageRohan Ramakrishna
Department of Neurological Surgery, Harborview Medical Center, University of Washington Medical Center, Seattle, Washington 98104, USA
Neurosurgery 67:110-7; discussion 117. 2010..The sequelae of aneurysmal subarachnoid hemorrhage (SAH) include vasospasm and hydrocephalus...
Cerebrovascular bypass and aneurysm trapping for the treatment of an A2-segment anterior cerebral artery pseudoaneurysm and herniation through a skull base defect following traumaBrian P Walcott
Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, White Building Room 502, Boston, MA 0211H, USA
J Clin Neurosci 19:149-51. 2012..We present a unique case of a traumatic proximal anterior cerebral artery pseudoaneurysm, herniating through a skull base defect. Treatment consisted of aneurysm trapping and bypass with skull base reconstruction...
Vertebral artery pexy for microvascular decompression of the facial nerve in the treatment of hemifacial spasmManuel Ferreira
Department of Neurosurgery, University of Washington, Seattle, Washington 98104 2499, USA
J Neurosurg 114:1800-4. 2011..The authors report the use of a new technique of VA pexy to the petrous or clival dura mater in patients with HFS attributed to a severely ectatic and tortuous VA, and detail the results in a series of patients...
Endoscope-assisted microsurgery for microvascular compression syndromesRamin Rak
Department of Neurosurgery, North Shore University Hospital, 865 Northern Boulevard, Great Neck, NY 11021, USA
Neurosurgery 54:876-81; discussion 881-3. 2004..CONCLUSION: The endoscope is a useful adjunct to MVD in the treatment of trigeminal neuralgia, hemifacial spasm, and disabling positional vertigo or tinnitus...
A case of high-grade undifferentiated sarcoma after surgical resection and stereotactic radiosurgery of a vestibular schwannomaTong Yang
Department of Neurosurgery, University of Washington, School of Medicine, Seattle, Washington
Skull Base 20:179-83. 2010..Such observations can influence clinical decisions regarding the choice of treatment modalities...
Cutaneous metastasis from an intracranial glioblastoma multiformePatricio Figueroa
Department of Dermatology, The George Washington University Medical Center, Washington, DC, USA
J Am Acad Dermatol 46:297-300. 2002..Although metastasis of this tumor is not uncommon, metastasis to the skin has never been reported. To our knowledge, this is the first reported case of cutaneous metastasis from glioblastoma in the world literature...
["How I do it" no. 6, a case with a giant petroclival meningioma presented with progressive ataxia: how should this case be managed?]Kenji Ohata
Department of Neurosurgery, North Shore University Hospital, 300 Community Drive, Manhasset, New York 1103, USA
No Shinkei Geka 31:1125; discussion 1126-37. 2003
Endoscope-assisted microsurgery for intracranial aneurysmsChandrasekar Kalavakonda
Mid-Atlantic Brain and Spine Institutes, 3301 Woodburn Road, Annandale, VA 22003, USA
Neurosurgery 51:1119-26; discussion 1126-7. 2002..quot;..
Endoscopic microneurosurgery: usefulness and cost-effectiveness in the consecutive experience of 210 patientsAkio Morita
Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Neurosurgery 58:315-21; discussion 315-21. 2006..Indications, usefulness, and cost-effectiveness of the endoscope in routine microneurosurgery are not clear. To delineate such aspects, we assessed our experience of endoscopic application and additional cost to use an endoscope...
The cosmetic aspects of neurosurgeryLaligam N Sekhar
Mid Atlantic Brain and Ear and Spine Institutes, 3301 Woodburn Road, Suite 202, Annandale, VA 22003, USA
Neurosurg Clin N Am 13:401-3. 2002..quot;..
The preservation and reconstruction of cerebral veins and sinusesLaligam N Sekhar
Mid Atlantic Brain and Spine Institutes, Annandale, VA 22003, USA
J Clin Neurosci 9:391-9. 2002..Even in such patients, some neurological manifestations may follow, when the collaterals are poor...
Cerebral revascularization for aneurysms and tumorsLaligam N Sekhar
Mid Atlantic Brain and Spine Institutes, Annandale, Virginia 22003, USA
Neurosurgery 50:321-31. 2002..To discuss the indications, techniques, pitfalls, complication avoidance, and management of cerebral revascularization techniques for the treatment of aneurysms and cranial base tumors...
Nonvestibular schwannomas of the brain: a 7-year experienceSajjan Sarma
Mid-Atlantic Brain and Spine Institutes, Annandale, Virginia, USA
Neurosurgery 50:437-48; discussion 438-9. 2002..CONCLUSION: Nonvestibular schwannomas can be treated via microsurgical excision, with excellent functional results. Recurrence is rare after total tumor excision, although much longer follow-up monitoring is required...
Do skull base lesions and their surgical treatment cause epileptic seizures?Sigmund Jenssen
Department of Neurology, Drexel Medical College, Philadelphia, PA 19109, USA
Clin Neurol Neurosurg 109:406-8. 2007..Few reports exist on the risk of seizures with skull base lesions and their surgical treatment...
