Research Topics
| ANDREW SCHAFERSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
ThrombocytosisAndrew I Schafer
Department of Medicine, University of Pennsylvania School of Medicine and University of Pennsylvania Health System, Philadelphia 19104, USA
N Engl J Med 350:1211-9. 2004
Crafting an effective strategic plan for a department of medicineAndrew I Schafer
Department of Medicine at the University of Pennsylvania School of Medicine, Philadelphia, USA
Am J Med 118:315-20. 2005
Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemiaAndrew I Schafer
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Blood 107:4214-22. 2006....
Thrombocytosis: When is an incidental finding serious?Andrew I Schafer
Department of Medicine, University of Pennsylvania School of Medicine, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA
Cleve Clin J Med 73:767-74. 2006..This article discusses how to classify thrombocytosis and identify which patients require treatment, describes the characteristic complications that may arise, and provides an algorithm for management...
Thrombocytosis: too much of a good thing?Andrew I Schafer
Department of Medicine, The Bob and Vivian Smith Professor of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Trans Am Clin Climatol Assoc 113:68-76; discussion 76-7. 2002..It is proposed that bleeding and thrombosis could be due to vascular abnormalities that result from dysfunctional hematopoietic stem cell-derived endothelial cells...
YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet functionDavid A Tulis
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Biochem Biophys Res Commun 291:1014-21. 2002..These results suggest that YC-1 is a potent, physiologically active agent with major anti-proliferative and anti-platelet properties that may provide protection against vascular injury through cGMP-dependent mechanisms...
The fault lines of academic medicineAndrew I Schafer
Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
Perspect Biol Med 45:416-25. 2002..The organization of a successful medical school or department must be dynamic, constantly serving its constituents to accommodate progress and change and to promote optimal structure for academic productivity...
Genetic and acquired determinants of individual variability of response to antiplatelet drugsAndrew I Schafer
Circulation 108:910-1. 2003
Physiologic cyclic stretch inhibits apoptosis in vascular endotheliumXiao-ming Liu
VA Medical Center and the Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
FEBS Lett 541:52-6. 2003..The ability of physiologic cyclic stretch to inhibit EC apoptosis may provide a previously unrecognized mechanism by which hemodynamic forces exert an anti-atherogenic effect...
Research Grants
- REGULATION OF PLATELET/ENDOTHELIAL INTERACTIONSANDREW SCHAFER; Fiscal Year: 2001..The goal is to establish CO as an important vascular cell messenger molecule that modulates blood fluidity and may prove to be a target for therapy of vascular disorders. ..
- VASCULAR CELL CATIONIC AMINO ACID TRANSPORT & METABOLISMANDREW SCHAFER; Fiscal Year: 2002..Elucidation of the molecular mechanisms that modulate the response to vascular injury will provide new rational targets for therapeutic intervention. ..
- REGULATION OF PLATELET-ENDOTHELIAL INTERACTIONSANDREW SCHAFER; Fiscal Year: 2006....
- REGULATION OF PLATELET-ENDOTHELIAL INTERACTIONSANDREW SCHAFER; Fiscal Year: 1993..Understanding the modulation of platelet and EC actions and interactions by the fibrinolytic system will have pathophysiologic and pharmacologic importance in clarifying our concepts of thrombosis and hemostasis...
- Revitalization of the Nation?s Physician-Scientist WorkforceANDREW SCHAFER; Fiscal Year: 2007..The conference is therefore only a starting point for implementing a long-term initiative for influencing and counteracting the decline in the physician-scientist workforce. ..
