Research Topics
| Asim SahaSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Dendritic cells pulsed with an anti-idiotype antibody mimicking Her-2/neu induced protective antitumor immunity in two lines of Her-2/neu transgenic miceAsim Saha
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA
Cell Immunol 263:9-21. 2010..Tumor growth inhibition was associated with the induction of Her-2/neu-specific immune responses. These data suggest the potential use of anti-Id antibody 6D12 as a vaccine for immunotherapy of Her-2/neu-positive human cancer...- Combination of CTL-associated antigen-4 blockade and depletion of CD25 regulatory T cells enhance tumour immunity of dendritic cell-based vaccine in a mouse model of colon cancerAsim Saha
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA
Scand J Immunol 71:70-82. 2010..These results provide evidence that simultaneous blockade of T-cell regulatory pathways is a promising approach for the induction of therapeutic antitumour immunity against CEA(+) colon carcinoma... - Generation of Her-2/neu vaccine utilizing idiotypic network cascadeSmarajit Pal
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
Cancer Biol Ther 6:1916-25. 2007..These data suggest the potential use of 6D12 as a vaccine for Her-2/neu-positive human cancer... - Stimulatory effects of CpG oligodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic miceAsim Saha
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA
Int J Cancer 124:877-88. 2009..These results provide evidence that vaccination with antigen-pulsed DC with CpG ODN as adjuvant can lead to effective tumor regression and long-term survival in a murine model of colon carcinoma... - Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigenAsim Saha
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0509, USA
Cancer Res 67:2881-92. 2007..These results suggest the potential use of this vaccination strategy for future clinical applications... - Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigenAsim Saha
Department of Internal Medicine, University of Cincinnati, Cincinnati, OH45267, USA
Immunology 118:483-96. 2006..The adoptive transfer experiments also suggested the role of both CD4+ and CD8+ T cells in this model system. Furthermore, mice that had rejected C15 tumour growth, developed tumour-specific immunological memory... - Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic miceAsim Saha
Department of Internal Medicine and the Barrett Cancer Center, University of Cincinnati, Cincinnati, OH 45267, USA
Cancer Res 64:4995-5003. 2004.... - CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic miceAsim Saha
Department of Internal Medicine and the Barrett Cancer Center, University of Cincinnati, OH, USA
Cancer Immunol Immunother 55:515-27. 2006..These findings suggest that 3H1-CpG vaccinations can break peripheral tolerance to CEA and induce protective antitumor immunity in this murine model transgenic for human CEA... - Anti-tumor immunity induced by an anti-idiotype antibody mimicking human Her-2/neuKartik Mohanty
Department of Internal Medicine, University of Cincinnati, The Vontz Center for Molecular Studies, 3125 Eden Avenue, Cincinnati, OH 45267, USA
Breast Cancer Res Treat 104:1-11. 2007..These data suggest that anti-Id 6D12 vaccine can induce protective Her-2/neu specific antitumor immunity and may serve as a potential network antigen for the treatment of patients with Her-2/neu-positive tumors... - Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunityAsim Saha
Department of Internal Medicine and the Barrett Cancer Center, University of Cincinnati, Cincinnati, Ohio 45267, USA
Cancer Res 63:2844-54. 2003..The tumor rejection in 3H1-pulsed DC-treated mice was associated with the induction of a memory response that helped those mice to survive a second challenge with a lethal dose of C15 cells... - Carcinoembryonic antigen transgenic mouse models for immunotherapy and development of cancer vaccinesMalaya Bhattacharya-Chatterjee
University of Cincinnati Medical Center, Cincinnati, Ohio, USA
Curr Protoc Immunol . 2008.... - Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigenRathindra Nath Baral
Department of Internal Medicine and the Barrett Cancer Center, University of Cincinnati, Cincinnati, OH 45267, USA
Cancer Immunol Immunother 52:317-27. 2003..Thus, CpG ODN 1826 was faster than FA in increasing anti-tumor immunity induced by anti-Id 3H1 immunization in this prophylactic model...