Research Topics
| T C RykenSummaryAffiliation: University of Iowa Country: USA Publications
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Detail Information
Publications
Modification of reference array attachment for image guided neurosurgery: direct cranial fixationTimothy C Ryken
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Technol Cancer Res Treat 1:401-4. 2002..The successful application of the modified system to two operative cases is described...
Evidence-based review of the surgical management of vertebral column metastatic diseaseTimothy C Ryken
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Neurosurg Focus 15:E11. 2003..The purpose of this review was to determine the foundation in the literature of views favoring surgical intervention for spinal metastatic disease...
Image-based drill templates for cervical pedicle screw placementTimothy C Ryken
Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
J Neurosurg Spine 10:21-6. 2009..The goal of the study was to assess the accuracy of a drill template in the placement of cervical PSs at a single vertebral level...
Engineering patient-specific drill templates and bioabsorbable posterior cervical plates: a feasibility studyTimothy C Ryken
Department of Nuerosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
J Neurosurg Spine 10:129-32. 2009..In this study, the authors explore the use of computer-generated templates and introduce their methods for creating custom, bioabsorbable posterior cervical implants...
Ultrasonographic guidance for spinal extracranial radiosurgery: technique and application for metastatic spinal lesionsT C Ryken
Department of Neurosurgery, University of Iowa, Iowa City, Iowa 52242 1077, USA
Neurosurg Focus 11:e8. 2001..In this report the authors describe this technique as applied to the treatment of localized metastatic spinal disease...
Initial clinical experience with frameless stereotactic radiosurgery: analysis of accuracy and feasibilityT C Ryken
Department of Neurosurgery, University of Iowa College of Medicine, Iowa City, IA, USA
Int J Radiat Oncol Biol Phys 51:1152-8. 2001..CONCLUSION: Our initial clinical experience with stereotactic radiotherapy using the infrared camera guidance system was promising, demonstrating clinical feasibility and accuracy comparable to many frame-based systems...
Rapid prototype patient-specific drill template for cervical pedicle screw placementBrent D Owen
Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Comput Aided Surg 12:303-8. 2007..To assess the feasibility and accuracy of a drill template for the placement of a cervical pedicle screw in a single vertebral level...
Effect of specimen fixation method on pullout tests of pedicle screwsM Pfeiffer
Iowa Spine Research Center, University of Iowa, Iowa City, USA
Spine (Phila Pa 1976) 21:1037-44. 1996..g., with a latex wrapping) or document post-test (e.g., through the methods described in this article) that intrusion did not occur for the specimens included in the analysis...
Fluid-attenuated inversion-recovery MR imaging in assessment of intracranial oligodendrogliomasMatthew L White
Department of Radiology, University of Iowa College of Medicine, Iowa City, IA 52242 1077, USA
Comput Med Imaging Graph 29:279-85. 2005..Our results demonstrate that the FLAIR sequence can replace the T2-weighted FSE sequence for evaluating oligodendrogliomas...
Can tumor contrast enhancement be used as a criterion for differentiating tumor grades of oligodendrogliomas?Matthew L White
Department of Radiology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
AJNR Am J Neuroradiol 26:784-90. 2005..Some authors have even used contrast enhancement as a criterion for their oligodendroglioma grading system. The purpose of our study was to evaluate if tumor contrast enhancement is a specific finding for anaplastic oligodendroglioma...
Complications of revision spinal surgeryKurt M Eichholz
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Neurosurg Focus 15:E1. 2003..The prognosis for a revision surgery can be predicted best by the patient's outcome after the primary surgery. As with any surgical procedure, patient selection is imperative for successful outcome...
The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guidelineMario Ammirati
Department of Neurosurgery, Ohio State University Medical Center, Columbus, OH, USA
J Neurooncol 96:85-96. 2010..What evidence is available regarding the use of whole brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), surgical resection or chemotherapy for the treatment of recurrent/progressive brain metastases?..
Image-guided stereotactic radiosurgery using a specially designed high-dose-rate linacJohn E Bayouth
Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
Med Dosim 32:134-41. 2007..5 mm for extracranial applications. Because stereotactic IGRT can require significantly longer times for treatment delivery, the advantages of the high-dose-rate design and its direct impact on IGRT are discussed...
Ultrasound-guided extracranial radiosurgery: technique and applicationSanford L Meeks
Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, USA
Int J Radiat Oncol Biol Phys 55:1092-101. 2003..In this paper, we describe the system and its initial clinical application in the treatment of localized metastatic disease...
Radiotoxicity after conformal radiation therapy for benign intracranial tumorsMark C Smith
Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Neurosurg Clin N Am 17:169-80, vii. 2006..This article reviews radiotoxicity after conformal radiation therapy for acoustic schwannomas, skull base meningiomas, and pituitary adenomas...
Assessment of unicortical and bicortical fixation in a quasistatic cadaveric model. Role of bone mineral density and screw torqueT C Ryken
Division of Neurosurgery, University of Iowa, Iowa City, USA
Spine (Phila Pa 1976) 20:1861-7. 1995..RESULTS. Unicortical screw placement resulted in inadequate stabilization in half of the cervical specimens. CONCLUSIONS. Our results suggest that, for the Caspar screw, bicortical fixation provides greater flexion-extension stability...
Human astrocytomas co-expressing Fas and Fas ligand also produce TGFbeta2 and Bcl-2B Frankel
Department of Neurosurgery, SUNY Health Science Center at Syracuse, NY 13210, USA
J Neurooncol 44:205-12. 1999..002) and Bcl-2 (p < 0.005) production. We conclude that Fas and FasL are frequently co-expressed in human astrocytomas and these tumors are likely to produce other immunosuppressive and antiapoptotic factors such as TGFbeta2 and Bcl-2...
The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guidelineSteven N Kalkanis
Department of Neurosurgery, Henry Ford Health System, 2799 West Grand Blvd, K 11, Detroit, MI 48202, USA
J Neurooncol 96:33-43. 2010..There is insufficient evidence to make a recommendation for patients with poor performance scores, advanced systemic disease, or multiple brain metastases...
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guidelineMark E Linskey
Department of Neurosurgery, University of California Irvine Medical Center, Orange, CA, USA
J Neurooncol 96:45-68. 2010....
Trends in brain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to 2001Sundeep Deorah
Department of Epidemiology, College of Public Health, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Neurosurg Focus 20:E1. 2006..The incidence rate of brain cancer in the US is gradually declining, but the rising trend of GBM combined with its poor survival rate is disconcerting and needs further exploration...
The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topicsJeffrey J Olson
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
J Neurooncol 96:115-42. 2010..What evidence is available regarding the emerging and investigational therapies for the treatment of metastatic brain tumors?..
Tumor Fas (APO-1/CD95) up-regulation results in increased apoptosis and survival times for rats with intracranial malignant gliomasB Frankel
Department of Neurosurgery, State University of New York Upstate Medical University, Syracuse 13210, USA
Neurosurgery 49:168-75; discussion 175-6. 2001..However, little is known regarding the effects of Fas expression on glioma viability in vivo. The goal of this study was to clarify the relationships among Fas expression, apoptosis, and survival rates for high-grade astrocytomas...
Techniques for cervical interbody graftingTimothy C Ryken
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
J Neurosurg Spine 11:203-20. 2009..The objective of this systematic review was to use evidence-based medicine to determine the efficacy of interbody graft techniques...
Management of newly diagnosed glioblastoma: guidelines development, value and applicationJeffrey J Olson
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322, USA
J Neurooncol 93:1-23. 2009....
Cervical surgical techniques for the treatment of cervical spondylotic myelopathyPraveen V Mummaneni
Department of Neurosurgery, University of California at San Francisco, California, USA
J Neurosurg Spine 11:130-41. 2009..The objective of this systematic review was to use evidence-based medicine to compare the efficacy of different surgical techniques for the treatment of cervical spondylotic myelopathy (CSM)...
Cervical laminectomy for the treatment of cervical degenerative myelopathyTimothy C Ryken
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
J Neurosurg Spine 11:142-9. 2009..The objective of this systematic review was to use evidence-based medicine to examine the efficacy of cervical laminectomy for the treatment of cervical spondylotic myelopathy (CSM)...
Cervical laminoforaminotomy for the treatment of cervical degenerative radiculopathyRobert F Heary
Department of Neurosurgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
J Neurosurg Spine 11:198-202. 2009..The objective of this systematic review was to use evidence-based medicine to examine the efficacy of posterior laminoforaminotomy in the treatment of cervical radiculopathy...
Initial clinical experience with frameless radiosurgery for patients with intracranial metastasesReena Kamath
Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, IA, USA
Int J Radiat Oncol Biol Phys 61:1467-72. 2005..Practical noninvasive delivery makes treatment and potential retreatment to avoid WBRT more feasible...
The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guidelineTimothy C Ryken
Department of Neurosurgery, Iowa Spine and Brain Institute, Iowa City, IA, USA
J Neurooncol 96:103-14. 2010..2) comparison of different doses of steroid therapy...
Protracted radiotherapy treatment duration in medulloblastomaArnold C Paulino
Department of Radiation Oncology, The University of Iowa, College of Medicine and Children s Hospital of Iowa, Iowa City, Iowa, USA
Am J Clin Oncol 26:55-9. 2003....
Enhanced anatomic visualization with ultrasound-assisted intracranial image-guidance in neurosurgeryAlexandre M N Marinho
Department of Neurosurgery, University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
Technol Cancer Res Treat 1:181-6. 2002..The accuracy of navigation depends on the identification of the anatomic structures. Despite some limitations of the ultrasound images, the ability to compare preoperative MRI and intraoperative ultrasound proved useful to the surgeon...
Atypical teratoid/rhabdoid tumor case report: treatment with surgical excision, radiation therapy, and alternative medicinesTerese L Howes
Department of Radiation Oncology, University of Iowa Hospitals and Clinics, W 189 Z GH, Iowa City, IA 52242, USA
J Neurooncol 72:85-8. 2005..The patient has been maintained on an extensive regimen of alternative therapies since completion of radiation therapy...
Radiation therapy of pathologically confirmed newly diagnosed glioblastoma in adultsJohn Buatti
Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA
J Neurooncol 89:313-37. 2008
Radiation induced adult medulloblastoma: a case reportTerese L Howes
Department of Radiation Oncology, University of Iowa Health Care, W189Z General Hospital, Iowa City, IA 52242, USA
J Neurooncol 80:191-4. 2006..This is the first reported case of radiation induced adult medulloblastoma...
Anatomic visualization with ultrasound-assisted intracranial image guidance in neurosurgery: a report of 30 patientsWilson Z Ray
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
J Am Coll Surg 199:338-43. 2004
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant gliomaGreg Foltz
Neurogenomic Research Laboratory, Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Cancer Res 66:6665-74. 2006....
Surgical management of newly diagnosed glioblastoma in adults: role of cytoreductive surgeryTimothy C Ryken
Department of Neurosurgery, University of Iowa College of Medicine, Iowa City, IA, USA
J Neurooncol 89:271-86. 2008
Genetic characterization of commonly used glioma cell lines in the rat animal model systemZita A Sibenaller
Department of Neurosurgery, University of Iowa Hospitals, Iowa City, Iowa 52242, USA
Neurosurg Focus 19:E1. 2005....
Low-grade gliomas: answering one question in a myriad of new questionsJohn M Buatti
J Clin Oncol 20:2223-4. 2002
Management of malignant glioma: steady progress with multimodal approachesLynn S Ashby
Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA
Neurosurg Focus 20:E3. 2006..Future treatment strategies may include a wide variety of biological response modifiers, but will need to continue to address local control with surgery, radiation, and adjuvant chemotherapy...
Guidelines for the management of acute cervical spine and spinal cord injuriesMark N Hadley
University of Alabama/Neurosurgery, Birmingham, Alabama, USA
Clin Neurosurg 49:407-98. 2002
Diagnosis of malignant glioma: role of neuropathologyDaniel J Brat
Department of Pathology and Laboratory Medicine, Emory University Hospital, G-169, 1364 Clifton Rd. NE, Atlanta, GA 30322, USA
J Neurooncol 89:287-311. 2008
