Research Topics
| Robert RubinSummaryAffiliation: University of New Mexico Country: USA Publications
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Detail Information
Publications
Drug-induced lupusRobert L Rubin
Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
Toxicology 209:135-47. 2005..These findings, as well as evidence for thymic function in drug-induced lupus patients, support the concept that abnormalities during T-cell selection in the thymus initiate autoimmunity...
Effect of cigarette smoke on autoimmunity in murine and human systemic lupus erythematosusRobert L Rubin
Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
Toxicol Sci 87:86-96. 2005..Inhaled cigarette smoke appears to have a long-lasting immunosuppressive effect on T-cell-dependent autoimmune responses, although autoantibodies increase to supra-elevated levels after the suppressive effect has abated...
Plasticity in the positive selection of T cells: affinity of the selecting antigen and IL-7 affect T cell responsivenessRobert L Rubin
Department of Molecular Genetics and Microbiology, MSC08 4660, 1 University of New Mexico Medical School, Albuquerque, NM 87131, USA
Int Immunol 17:959-71. 2005..Overall, this study demonstrates that the responsiveness of T cells is not rigidly controlled and that the presence of IL-7 during T cell development has the potential to negate central T cell tolerance and produce autoreactive T cells...
Rapid detection of anti-chromatin autoantibodies in human serum using a portable electrochemical biosensorKonstantin N Konstantinov
Dept of Internal Medicine, University of New Mexico Health Sciences Center, USA
Biosens Bioelectron 24:1949-54. 2009..These results demonstrate the applicability of this technology to the rapid measurement of a clinically relevant analyte with an apparatus of potential simplicity and low cost...
