Research Topics
Species | George M RodgersSummaryAffiliation: University of Utah Country: USA Publications
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Publications
Superwarfarin poisoning: a report of two cases and review of the literatureJoseph E Spahr
Division of Hematology and Oncology, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, UT 84112 5550, USA
Am J Hematol 82:656-60. 2007..Finally, the significance of "lacing" drugs of abuse with superwarfarin to potentiate their effect is discussed, as well as the complications that could develop from such a habit...- Role of antithrombin concentrate in treatment of hereditary antithrombin deficiency. An updateGeorge M Rodgers
University of Utah Medical Center, Division of Hematology, 30 North 1900 East, Salt Lake City, UT 84132, USA
Thromb Haemost 101:806-12. 2009..The objective of this review is to discuss hereditary AT deficiency and the role of AT replacement therapy in the treatment of patients with this congenital disorder... - Guidelines for the use of erythropoietic growth factors in patients with chemotherapy-induced anemiaGeorge M Rodgers
Department of Medicine, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Oncology (Williston Park) 20:12-5. 2006.... - Immune-mediated coagulopathy associated with topical bovine thrombin: review of the pediatric literatureGeorge M Rodgers
Division of Hematology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
J Pediatr Hematol Oncol 33:86-8. 2011..Most of the clinical information on this coagulopathy is in the adult medical literature. This article reviews the literature on pediatric cases with this coagulopathy and summarizes clinical outcomes and effective therapies... - Perioperative management of antithrombotic therapy in cardiovascular patientsMarc T Nuttall
Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
Methodist Debakey Cardiovasc J 7:10-4. 2011.... - Discard tubes are not necessary when drawing samples for specialized coagulation testingKristi J Smock
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
Blood Coagul Fibrinolysis 21:279-82. 2010..Our data suggest that discard tubes are not necessary when drawing samples for specialized coagulation testing... - Successful management of intra-abdominal hemorrhage in the presence of severe alcoholic liver disease with activated recombinant factor VII (rFVIIa; NovoSeven): a case report and review of the literature on approved and off-label use of rFVIIaNeeraj Agarwal
Division of Hematology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Blood Coagul Fibrinolysis 18:205-7. 2007..We review the current literature on the approved and off-label use of activated recombinant factor VII... - Pediatric reference intervals for uncommon bleeding and thrombotic disordersMichele M Flanders
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
J Pediatr 149:275-7. 2006..All analytes exhibited at least some age dependence in late childhood and adolescence either when compared against adult values or when medians for children were regressed against age... - Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practiceRyan Wilcox
Department of Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA
Hosp Pract (Minneap) 39:23-34. 2011..We also provide an approach to patients on dabigatran etexilate who are bleeding, have a suspected therapeutic failure, or require periprocedural management... - Effects of EDTA on routine and specialized coagulation testing and an easy method to distinguish EDTA-treated from citrated plasma samplesRonda A Crist
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City ARUP Hemostasis Thrombosis Laboratory, Salt Lake City, UT 84108, USA
Lab Hematol 15:45-8. 2009..We confirm that EDTA has effects on coagulation assays. Sodium tetraphenylborate testing is a quick, simple, and inexpensive method for coagulation laboratories to identify samples erroneously submitted in EDTA... - Weight-based dosing of enoxaparin for VTE prophylaxis in morbidly obese, medically-Ill patientsMatthew T Rondina
Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Thromb Res 125:220-3. 2010.... - Established venous thromboembolism therapies: heparin, low molecular weight heparins, and vitamin K antagonists, with a discussion of heparin-induced thrombocytopeniaRobert C Pendleton
Department of Medicine, University Healthcare Thrombosis Service, University of Utah, 50 North Medical Drive, Room 4B120, Salt Lake City, UT 84132, USA
Clin Chest Med 31:691-706. 2010..Further, in parallel with the evolution of VTE treatment, there have been remarkable advances in our understanding of heparin-induced thrombocytopenia, a prothrombotic complication of parenteral anticoagulant use... - Establishing an anemia clinic for optimal erythropoietic-stimulating agent use in hematology-oncology patientsJeffrey A Gilreath
Huntsman Cancer Institute, Department of Pharmacy Services, University of Utah Hospitals and Clinics, Salt Lake City, Utah 84112, USA
J Natl Compr Canc Netw 6:577-84. 2008..The pharmacist's role is justified in this clinic model through increased adherence to evidence-based practice guidelines and decreased costs associated with ESA therapy... - Prevalence of heparin in samples submitted for lupus anticoagulant testingNikhil A Sangle
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Lab Hematol 17:6-11. 2011..We searched our reference laboratory database to determine the prevalence of heparin in samples submitted for LA testing... - Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular eventsDavid T Yang
Department of Pathology, The University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
Am J Clin Pathol 126:411-5. 2006..3; R = 0.667) and a lack of correlation of both with hs-CRP suggests that factor XI is not an acute phase reactant. Our findings suggest an association between elevated factor XI activity and stroke... - The treatment of venous thromboembolism in special populationsMatthew T Rondina
The University of Utah Health Sciences Center, Department of Internal Medicine, Salt Lake City, UT 84132, USA
Thromb Res 119:391-402. 2007..This review summarizes the current data for these special patient populations with venous thromboembolism and provides our recommendations for management... - Cancer- and chemotherapy-induced anemiaGeorge M Rodgers
Huntsman Cancer Institute, University of Utah, Utah, USA
J Natl Compr Canc Netw 6:536-64. 2008 - Pediatric reference intervals for seven common coagulation assaysMichele M Flanders
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84132, USA
Clin Chem 51:1738-42. 2005 - A necessary detourRobert C Pendleton
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
Am J Med 119:651-3. 2006 - Argatroban dosing of patients with heparin-induced thrombocytopenia and an elevated aPTT due to antiphospholipid antibody syndromeRobert Pendleton
University of Utah Medical Center, Salt Lake City, UT 84132-0100, USA
Ann Pharmacother 40:972-6. 2006..CONCLUSIONS: Use of a fixed-dose argatroban regimen without laboratory monitoring is a potential management strategy for patients with HIT/HITTS and an elevated baseline aPTT due to APS... - The accuracy of activated partial thromboplastin times when drawn through a peripherally inserted central catheterMatthew T Rondina
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Am J Hematol 82:738-9. 2007..There were no clinically significant differences between aPTT values from the two samples. Using the PICC to obtain blood for the measurement of aPTT is accurate and may reduce the need for peripheral VPs... - The utility of patient characteristics in predicting severe ADAMTS13 deficiency and response to plasma exchangeMelissa J Bentley
Department of Internal Medicine, University of Utah Health Sciences Center, and ARUP Laboratories, Salt Lake City, Utah, USA
Transfusion 50:1654-64. 2010..The availability of ADAMTS13 testing has improved diagnostic accuracy and appropriate selection of patients who are most likely to respond to plasma exchange... - Home prothrombin time monitoring: a literature analysisDavid T Yang
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Am J Hematol 77:177-86. 2004..There are accurate and reliable instruments available, but paramount to the success of home PT monitoring is sound patient selection, appropriate patient training, and consistent quality control... - Treatment of immune-mediated thrombocytopenia purpura with concurrent intravenous immunoglobulin and platelet transfusion: a retrospective review of 40 patientsJoseph E Spahr
Division of Hematology and Oncology, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah 84112 5550, USA
Am J Hematol 83:122-5. 2008..Our approach for administration of IVIg and platelets concurrently was associated with minimal side effects, resolution of bleeding, ability to safely undergo procedures, and rapid restoration of adequate platelet counts... - Management of cancer-associated thrombotic microangiopathy: what is the right approach?Theresa L Werner
Division of Hematology, University of Utah Hospitals and Clinics, Salt Lake City, Utah, USA
Am J Hematol 82:295-8. 2007..Here we address one approach of management of these patients with cancer-associated TMA... - An inherited disorder with splenomegaly, cytopenias, and vision lossSrinivas K Tantravahi
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Am J Med Genet A 158:475-81. 2012..Despite numerous medical and ophthalmic evaluations, no diagnosis has been discovered... - Comparison of five thrombin time reagentsMichele M Flanders
ARUP Laboratories, Salt Lake City, UT 84108, USA
Clin Chem 49:169-72. 2003 - Laboratory evaluation of aspirin responsivenessKristi J Smock
Department of Pathology, University of Utah Health Sciences Center and ARUP Laboratories, Salt Lake City, Utah, USA
Am J Hematol 85:358-60. 2010..This article summarizes available laboratory testing of aspirin response with focus on technical issues, limitations, and current opinion on the utility of routine patient testing... - The inherited thrombophilias: genetics, epidemiology, and laboratory evaluationGlenn S Buchanan
Department of Internal Medicine, University of Utah Health Sciences Center, 30 North 1900 East Medical Drive, Salt Lake City, UT 84132, USA
Best Pract Res Clin Obstet Gynaecol 17:397-411. 2003..This chapter covers the genetics and epidemiology of the inherited thrombophilias and provides a useful, common-sense approach to the laboratory evaluation of a patient with venous thrombosis... - Regulation of ADAMTS13 expression in proliferating human umbilical vein endothelial cellsStephen J Kling
Division of Hematology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Pathophysiol Haemost Thromb 36:233-40. 2008..HUVECs rapidly increased ADAMTS13 mRNA in response to subconfluent conditions. This change in regulation, in turn, leads to increased ADAMTS13 protein production and activity by these proliferating cells... - Activation of coagulation during routine diagnostic coronary angiographyAnwar Tandar
Division of Cardiology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
EuroIntervention 3:345-9. 2007..These findings may not be pertinent to patients with thrombophilia... - Analytic validation and clinical evaluation of the STA LIATEST immunoturbidimetric D-dimer assay for the diagnosis of disseminated intravascular coagulationChristopher M Lehman
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City 84132-2501, USA
Am J Clin Pathol 122:178-84. 2004..A sensitive, immunoturbidimetric D-dimer assay, by itself provides excellent sensitivity and negative predictive value for the diagnosis of DIC... - Laboratory identification of lupus anticoagulantsKristi J Smock
ARUP Laboratories, Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
Am J Hematol 84:440-2. 2009..This article summarizes laboratory testing for LAs, with particular focus on technical issues and limitations of testing. Am. J. Hematol. 2009. (c) 2009 Wiley-Liss, Inc... - A second case of prothrombin Puerto Rico I in the United StatesStephen J Kling
Division of Hematology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
Am J Hematol 82:661-2. 2007..This case underscores the importance of family history in identifying rare bleeding disorders... - Parenteral iron therapy: a single institution's experience over a 5-year periodChristopher A Laman
Department of Pharmacy Services, Huntsman Cancer Institute, Salt Lake City, UT 84132, USA
J Natl Compr Canc Netw 3:791-5. 2005..There were no serious adverse events and no anaphylaxis was observed. Our results suggest that, if test doses and premedications are used, iron dextran is an acceptable product to treat iron deficiency... - Evaluation and performance characteristics of the STA-R coagulation analyzerMichele M Flanders
ARUP Laboratories, Salt Lake City, UT 84108, USA
Clin Chem 48:1622-4. 2002 - Cancer- and treatment-related anemiaGeorge M Rodgers
J Natl Compr Canc Netw 3:772-89. 2005 - Recombinant activated factor VII: a new weapon in the fight against hemorrhageD Ware Branch
Obstet Gynecol 101:1155-6. 2003 - High-molecular weight iron dextran: a wolf in sheep's clothing?George M Rodgers
J Am Soc Nephrol 19:833-4. 2008 - Venous thromboembolism prophylaxis in medically ill patients and the development of strategies to improve prophylaxis ratesJason M Stinnett
Mountain States Tumor Institute, Boise, Idaho, USA
Am J Hematol 78:167-72. 2005..Implementation of strategies to improve prophylaxis rates, including educational sessions and risk stratification guidelines, can be successful and improve identification and prophylaxis of this population... - Improving the laboratory diagnosis of heparin-induced thrombocytopeniaGeorge M Rodgers
Am J Med 114:609-10. 2003 - Elevated hemostatic factor levels as potential risk factors for thrombosisWayne L Chandler
Department of Laboratory Medicine, University of Washington, Seattle 98195, USA
Arch Pathol Lab Med 126:1405-14. 2002.... - Evaluation of a Russell's viper venom-based protein C assayMichele M Flanders
Thromb Haemost 92:430-1. 2004 - Intravenous ironMichael Auerbach
N Engl J Med 357:93-4. 2007