Research Topics
| J M ReinhardtSummaryAffiliation: University of Iowa Country: USA Publications
Research Grants
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Detail Information
Publications
Accurate measurement of intrathoracic airwaysJ M Reinhardt
Department of Biomedical Engineering, University of Iowa, Iowa City 52242, USA
IEEE Trans Med Imaging 16:820-7. 1997..Using CT scans of a physical phantom, we present results showing that the new approach is more accurate than the half-max method at estimating wall location for thin-walled airways...
Registration-based estimates of local lung tissue expansion compared to xenon CT measures of specific ventilationJoseph M Reinhardt
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA
Med Image Anal 12:752-63. 2008..Using 3D image registration to match images acquired at 10 cm H(2)O and 15 cm H(2)O airway pressures gave the best match between the average Jacobian and the xenon CT specific ventilation (linear regression, average r(2)=0.73)...
Registration-derived estimates of local lung expansion as surrogates for regional ventilationJoseph M Reinhardt
Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, USA
Inf Process Med Imaging 20:763-74. 2007..We compare lung expansion estimated across five pressure changes to a xenon CT based measure of specific ventilation, and have shown good agreement (linear regression, r2 = 0.89 during gas wash-in) in one animal...
Atlas-driven lung lobe segmentation in volumetric X-ray CT imagesLi Zhang
University of Iowa, Iowa City, IA 52242, USA
IEEE Trans Med Imaging 25:1-16. 2006..96 +/- 0.71 mm and the mean of the similarity indices between the manually defined and computer-defined lobe regions is 0.988. The results indicate a strong agreement between the automatic and manual lobe segmentations...
Automatic lung segmentation for accurate quantitation of volumetric X-ray CT imagesS Hu
Department of Biomedical Engineering, University of Iowa, Iowa City 52242, USA
IEEE Trans Med Imaging 20:490-8. 2001..8 pixels (0.54 mm). The mean intrasubject change in tissue content over the three scans was 2.75% +/- 2.29% (mean +/- standard deviation)...
4DCT-based measurement of changes in pulmonary function following a course of radiation therapyKai Ding
Department of Biomedical Engineering, The University of Iowa, Iowa City, Iowa 52242, USA
Med Phys 37:1261-72. 2010..In this article, the authors propose a method that quantitatively measures the regional changes in lung tissue function following a course of radiation therapy by using 4DCT and image registration techniques...
Rapid prototype patient-specific drill template for cervical pedicle screw placementBrent D Owen
Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Comput Aided Surg 12:303-8. 2007..To assess the feasibility and accuracy of a drill template for the placement of a cervical pedicle screw in a single vertebral level...
Establishing a normative atlas of the human lung: intersubject warping and registration of volumetric CT imagesBaojun Li
Department of Biomedical Engineering, University of Iowa, 1402 SC, Iowa City, IA 52242, USA
Acad Radiol 10:255-65. 2003....
Evaluation of lobar biomechanics during respiration using image registrationKai Ding
Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, USA
Med Image Comput Comput Assist Interv 12:739-46. 2009..The results show a superior-inferior gradient in the magnitude of lobar sliding. We compare whole-lung-based registration accuracy to lobe-by-lobe registration accuracy using vessel bifurcation landmarks...
Engineering patient-specific drill templates and bioabsorbable posterior cervical plates: a feasibility studyTimothy C Ryken
Department of Nuerosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
J Neurosurg Spine 10:129-32. 2009..In this study, the authors explore the use of computer-generated templates and introduce their methods for creating custom, bioabsorbable posterior cervical implants...
Image-based drill templates for cervical pedicle screw placementTimothy C Ryken
Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
J Neurosurg Spine 10:21-6. 2009..The goal of the study was to assess the accuracy of a drill template in the placement of cervical PSs at a single vertebral level...
Validation of retinal image registration algorithms by a projective imaging distortion modelSangyeol Lee
Department of Biomedical Engineering, The University of Iowa, Iowa City 52242, USA
Conf Proc IEEE Eng Med Biol Soc 2007:6472-5. 2007..The quantitative comparison for different registration methods is given in the experiment, so the registration performance is evaluated in an objective manner...
The comprehensive imaging-based analysis of the lung: a forum for team scienceEric A Hoffman
Department of Radiology, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA
Acad Radiol 11:1370-80. 2004
Smoothing lung segmentation surfaces in three-dimensional X-ray CT images using anatomic guidanceSoumik Ukil
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA
Acad Radiol 12:1502-11. 2005..Processes like lung image registration and lung atlas construction can be affected by such inconsistencies. Therefore there is a need for a more consistent lung surface near the mediastinum...
Segmentation and analysis of the human airway tree from three-dimensional X-ray CT imagesDeniz Aykac
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA
IEEE Trans Med Imaging 22:940-50. 2003..Compared to manual analysis on 3-mm-thick electron-beam CT images, the automatic approach has an overall airway branch detection sensitivity of approximately 73%...
Macro-optical color assessment of the pulmonary airways with subsequent three-dimensional multidetector-x-ray-computed-tomography assisted displayMelissa Suter
University of Iowa Hospitals and Clinics, Department of Internal Medicine, Iowa City, Iowa 52242, USA
J Biomed Opt 10:051703. 2005..The resulting 3-D true-color images of the pulmonary mucosa facilitate the combination of mucosal color and topography analysis as well as region of interest localization within the airway tree...
Maximizing quantitative accuracy of lung airway lumen and wall measures obtained from X-ray CT imagingOsama I Saba
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA
J Appl Physiol 95:1063-75. 2003....
Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and functionEric A Hoffman
Department of Radiology, University of Iowa, Iowa City, IA, USA
Acad Radiol 10:1104-18. 2003..Furthermore, there is the growing need for scanner manufacturers to focus on not just visually pleasing images, but on quantitatifiably accurate images...
Anatomy-guided lung lobe segmentation in X-ray CT imagesSoumik Ukil
Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, USA
IEEE Trans Med Imaging 28:202-14. 2009..The detected incomplete fissure is used to extrapolate and smoothly complete the fissure. We evaluate the method by testing on data sets from normal subjects and subjects with mild to moderate emphysema...
A process model for direct correlation between computed tomography and histopathology application in lung cancerJessica C Sieren
Department of Internal Medicine, C325 GH, University of Iowa, Iowa City, IA 55242, USA
Acad Radiol 17:169-80. 2010..In the past, the incorporation of histopathology into these multimodal datasets has been complicated by the large differences in image quality, content, and spatial association...
Automated early detection of diabetic retinopathyMichael D Abramoff
Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Ophthalmology 117:1147-54. 2010....
Breast MRI lesion classification: improved performance of human readers with a backpropagation neural network computer-aided diagnosis (CAD) systemLina Arbash Meinel
Department of Biomedical Engineering, The University of Iowa, Iowa City, Iowa 52242, USA
J Magn Reson Imaging 25:89-95. 2007..To develop and test a computer-aided diagnosis (CAD) system to improve the performance of radiologists in classifying lesions on breast MRI (BMRI)...
Automated quantification of inherited phenotypes from color images: a twin study of the variability of optic nerve head shapeLi Tang
Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Invest Ophthalmol Vis Sci 51:5870-7. 2010....
CT-measured regional specific volume change reflects regional ventilation in supine sheepMatthew K Fuld
Department of Anesthesiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Appl Physiol 104:1177-84. 2008..Regional sVol, which involves significantly reduced exposure to radiation and Xe gas compared with the Xe-CT method, represents a safe and efficient surrogate for measuring regional ventilation in experimental studies and patients...
Computed tomography studies of lung mechanicsBrett A Simon
Department of Anesthesiology, Tower 711, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287 8711, USA
Proc Am Thorac Soc 2:517-21, 506-7. 2005....
Three-dimensional human airway segmentation methods for clinical virtual bronchoscopyAtilla P Kiraly
Department of Computer Science and Engineering, Penn State University, PA, USA
Acad Radiol 9:1153-68. 2002..The times required for all segmentations were acceptable, and the results were suitable for the authors' VB application needs...
Integrated CT/bronchoscopy in the central airways: preliminary resultsMelissa J Suter
Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA
Acad Radiol 15:786-98. 2008..The goal of this work is to integrate complementary medical imaging datasets to form a synergistic description of the airways...
Research Grants
- Regional Lung Mechanics by 3D Image RegistrationJoseph Reinhardt; Fiscal Year: 2007..This information is now critical to the development and evaluation of new pulmonary disease therapies. ..
- Regional Lung Mechanics by 3D Image RegistrationJoseph M Reinhardt; Fiscal Year: 2010..This information is now critical to the development and evaluation of new pulmonary disease therapies. ..
