V Prakash Reddy

Summary

Affiliation: University of Missouri-Rolla
Country: USA

Publications

  1. ncbi Carnosine: a versatile antioxidant and antiglycating agent
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Sci Aging Knowledge Environ 2005:pe12. 2005
  2. ncbi Transition metal ion binding studies of carnosine and histidine: biologically relevant antioxidants
    Stephanie Velez
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    Colloids Surf B Biointerfaces 66:291-4. 2008
  3. ncbi Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Drug Discov Today 11:646-54. 2006
  4. ncbi NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide
    Nanditha G Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 20:57-66. 2010
  5. ncbi Oxidative stress in diabetes and Alzheimer's disease
    V Prakash Reddy
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 16:763-74. 2009
  6. ncbi Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies
    Nanditha Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, United States
    Bioorg Med Chem Lett 21:3957-61. 2011

Collaborators

Detail Information

Publications6

  1. ncbi Carnosine: a versatile antioxidant and antiglycating agent
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Sci Aging Knowledge Environ 2005:pe12. 2005
    ..AGEs are known contributors to the pathology of Alzheimer's disease, and carnosine therefore merits serious attention as a possible therapeutic agent...
  2. ncbi Transition metal ion binding studies of carnosine and histidine: biologically relevant antioxidants
    Stephanie Velez
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    Colloids Surf B Biointerfaces 66:291-4. 2008
    ..84+/-0.18, were found to be 71 and 1.1M(-1), respectively. The unexpectedly lower binding constant values of carnosine show the relatively minor role of the transition metal ion chelation in their antioxidant abilities...
  3. ncbi Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Drug Discov Today 11:646-54. 2006
    ....
  4. ncbi NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide
    Nanditha G Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 20:57-66. 2010
    ..From these studies, we suggest that Abeta-chelated Zn(II) is readily displaced by Cu(II) and Fe(III) ions and leads to a propagation of oxidative stress...
  5. ncbi Oxidative stress in diabetes and Alzheimer's disease
    V Prakash Reddy
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 16:763-74. 2009
    ....
  6. ncbi Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies
    Nanditha Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, United States
    Bioorg Med Chem Lett 21:3957-61. 2011
    ..These combined experimental and theoretical studies support the involvement of CDK5/p25 in the neuronal cell cycle re-entry...