Lawrence S Prince

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through Toll-like receptor 4 and NF-kappaB
    Lawrence S Prince
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Am J Physiol Lung Cell Mol Physiol 287:L999-1006. 2004
  2. ncbi Toll-like receptor signaling inhibits structural development of the distal fetal mouse lung
    Lawrence S Prince
    Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Dev Dyn 233:553-61. 2005
  3. ncbi NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression
    John T Benjamin
    Division of Neonatology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Immunol 185:4896-903. 2010
  4. ncbi FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation
    John T Benjamin
    Departments of Pediatrics, Children s Hospital of Alabama, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Physiol Lung Cell Mol Physiol 292:L550-8. 2007
  5. ncbi The role of integrin alpha8beta1 in fetal lung morphogenesis and injury
    John T Benjamin
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232 0493, USA
    Dev Biol 335:407-17. 2009
  6. ncbi Hyperoxia and apoptosis in developing mouse lung mesenchyme
    Heather I Dieperink
    Department of Pediatrics, University of Alabama at Birmingham, 35294, USA
    Pediatr Res 59:185-90. 2006
  7. ncbi Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse
    Hehai Wang
    Division of Neonatology, Department of Pediatrics, Vanderbilt University Medical Center, 1125 MRB IV, 2215 B Garland Avenue, Nashville, TN 37232 0656, USA
    Dev Biol 318:112-25. 2008

Collaborators

  • John T Benjamin
  • Yasutoshi Yamamoto
  • Hehai Wang
  • Timothy S Blackwell
  • Brian A Halloran
  • Heather I Dieperink
  • Riet Van Der Meer
  • Erin J Plosa
  • Billy J Carver
  • J Davin Miller
  • Jin Hua Liu
  • David C Gaston
  • Roy Zent
  • Lynn M Schnapp
  • B C Paria
  • Tianbing Ding
  • Naoko Brown
  • Jeff Reese
  • Rebekah J Smith
  • Timothy J Day
  • David R Kelly

Detail Information

Publications7

  1. ncbi Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through Toll-like receptor 4 and NF-kappaB
    Lawrence S Prince
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Am J Physiol Lung Cell Mol Physiol 287:L999-1006. 2004
    ..These data implicate an important signaling mechanism in chorioamnionitis and suggest the TLR4/NF-kappaB pathway can influence lung development...
  2. ncbi Toll-like receptor signaling inhibits structural development of the distal fetal mouse lung
    Lawrence S Prince
    Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Dev Dyn 233:553-61. 2005
    ..This mechanism may link innate immune signaling with defects in structural development of the fetal lung...
  3. ncbi NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression
    John T Benjamin
    Division of Neonatology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Immunol 185:4896-903. 2010
    ..These findings indicate that inflammatory signaling through NF-?B disrupts the normal expression of FGF-10 in fetal lung mesenchyme by interfering with the transcriptional machinery critical for lung morphogenesis...
  4. ncbi FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation
    John T Benjamin
    Departments of Pediatrics, Children s Hospital of Alabama, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Physiol Lung Cell Mol Physiol 292:L550-8. 2007
    ..Reduced FGF-10 expression may therefore link the innate immune system and impaired lung development in bronchopulmonary dysplasia...
  5. ncbi The role of integrin alpha8beta1 in fetal lung morphogenesis and injury
    John T Benjamin
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232 0493, USA
    Dev Biol 335:407-17. 2009
    ..Furthermore, our data suggest that disruption of the interactions between extracellular matrix and integrin alpha8beta1 may contribute to the pathogenesis of BPD...
  6. ncbi Hyperoxia and apoptosis in developing mouse lung mesenchyme
    Heather I Dieperink
    Department of Pediatrics, University of Alabama at Birmingham, 35294, USA
    Pediatr Res 59:185-90. 2006
    ..Our data suggest hyperoxia inhibits distal airway branching and directly induces apoptosis of the fetal mouse lung mesenchyme...
  7. ncbi Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse
    Hehai Wang
    Division of Neonatology, Department of Pediatrics, Vanderbilt University Medical Center, 1125 MRB IV, 2215 B Garland Avenue, Nashville, TN 37232 0656, USA
    Dev Biol 318:112-25. 2008
    ..These results provide the first evidence that ZO-1 is involved in blastocyst formation from the morula by regulating accumulation of fluid and differentiation of nonpolar blastomeres to polar trophoblast cells...