Charles Pollack

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 53:329-38. 2009
  2. ncbi Advanced management of acute iliofemoral deep venous thrombosis: emergency department and beyond
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 57:590-9. 2011
  3. ncbi 2007 focused update to the ACC/AHA guidelines for the management of patients with ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 52:344-355.e1. 2008
  4. ncbi Status report: Development of emergency medicine research since the Macy Report
    Charles V Pollack
    Department of Emergency Medicine at Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 42:66-80. 2003
  5. ncbi Application of the TIMI risk score for unstable angina and non-ST elevation acute coronary syndrome to an unselected emergency department chest pain population
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA
    Acad Emerg Med 13:13-8. 2006
  6. ncbi 2002 update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    University of Pennsylvania Health System, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 41:355-69. 2003
  7. ncbi Non-ST-elevation myocardial infarction patients who present during off hours have higher risk profiles and are treated less aggressively, but their outcomes are not worse: a report from Can Rapid Risk Stratification of Unstable Angina Patients Suppress AD
    Charles V Pollack
    Department of Emergency Medicine, University of Pennsylvania Hospital, Philadelphia, PA 19107, USA
    Crit Pathw Cardiol 8:29-33. 2009
  8. ncbi Wireless cardiac event alert monitoring is feasible and effective in the emergency department and adjacent waiting areas
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA
    Crit Pathw Cardiol 8:7-11. 2009
  9. ncbi 2004 American College of Cardiology/American Heart Association guidelines for the management of patients with ST-elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA
    Ann Emerg Med 45:363-76. 2005
  10. ncbi Emerging oral antiplatelet therapies for acute coronary syndromes
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, Philadelphia, PA 19107, USA
    Hosp Pract (Minneap) 38:29-37. 2010

Detail Information

Publications89

  1. ncbi Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 53:329-38. 2009
    ....
  2. ncbi Advanced management of acute iliofemoral deep venous thrombosis: emergency department and beyond
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 57:590-9. 2011
    ....
  3. ncbi 2007 focused update to the ACC/AHA guidelines for the management of patients with ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA 19107, USA
    Ann Emerg Med 52:344-355.e1. 2008
    ....
  4. ncbi Status report: Development of emergency medicine research since the Macy Report
    Charles V Pollack
    Department of Emergency Medicine at Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 42:66-80. 2003
    ....
  5. ncbi Application of the TIMI risk score for unstable angina and non-ST elevation acute coronary syndrome to an unselected emergency department chest pain population
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA
    Acad Emerg Med 13:13-8. 2006
    ....
  6. ncbi 2002 update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    University of Pennsylvania Health System, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 41:355-69. 2003
    ..Several of the modified and new recommendations again potentially affect ED management. These are presented and discussed here...
  7. ncbi Non-ST-elevation myocardial infarction patients who present during off hours have higher risk profiles and are treated less aggressively, but their outcomes are not worse: a report from Can Rapid Risk Stratification of Unstable Angina Patients Suppress AD
    Charles V Pollack
    Department of Emergency Medicine, University of Pennsylvania Hospital, Philadelphia, PA 19107, USA
    Crit Pathw Cardiol 8:29-33. 2009
    ..Although intensity of medical management was similar between groups, it was generally lower than current guidelines recommend, indicating potential for improvement in NSTEMI outcomes, regardless of time of presentation...
  8. ncbi Wireless cardiac event alert monitoring is feasible and effective in the emergency department and adjacent waiting areas
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA
    Crit Pathw Cardiol 8:7-11. 2009
    ..Wireless cardiac event monitoring is feasible in the ED, and improves the throughput of ED patients with worsening vital signs, and may improve overall patient safety, without an onerous burden of nonproductive alarms...
  9. ncbi 2004 American College of Cardiology/American Heart Association guidelines for the management of patients with ST-elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA
    Ann Emerg Med 45:363-76. 2005
    ..These are presented and discussed here...
  10. ncbi Emerging oral antiplatelet therapies for acute coronary syndromes
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, Philadelphia, PA 19107, USA
    Hosp Pract (Minneap) 38:29-37. 2010
    ....
  11. ncbi Pharmacological and mechanical revascularization strategies in STEMI: integration of the two approaches
    Charles Pollack
    Pennsylvania Hospital, Department of Emergency Medicine, University of Pennsylvania School of Medicine, 800 Spruce Street, Philadelphia, PA, 19107, USA
    J Invasive Cardiol 20:231-8. 2008
    ..This review outlines the growing list of treatment options available for these high-risk patients and highlights the advantages of some of the newer pharmacological strategies...
  12. ncbi Prospective evaluation of emergency department patients with potential coronary syndromes using initial absolute CK-MB vs. CK-MB relative index
    Otilia Capellan
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283, USA
    J Emerg Med 24:361-7. 2003
    ..The optimal test depends upon the relative importance of the sensitivity or specificity for clinical decision-making in an individual patient...
  13. ncbi Early glycoprotein IIb/IIIa inhibitor use for non-ST-segment elevation acute coronary syndrome: patient selection and associated treatment patterns
    James W Hoekstra
    Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Acad Emerg Med 12:431-8. 2005
    ....
  14. ncbi The elder patient with suspected acute coronary syndromes in the emergency department
    Jin H Han
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Acad Emerg Med 14:732-9. 2007
    ..To describe the evaluation and outcomes of elder patients with suspected acute coronary syndromes (ACS) presenting to the emergency department (ED)...
  15. ncbi Utility of platelet adp receptor antagonism in the emergency department: a review
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19107, USA
    J Emerg Med 24:45-54. 2003
    ..This review addresses the pathophysiology of atherothrombosis and evaluates the potential use of ADP receptor antagonists in the Emergency Department setting...
  16. ncbi The obesity paradox in non-ST-segment elevation acute coronary syndromes: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the American College of Cardiology/American Heart A
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA
    Am Heart J 152:140-8. 2006
    ..Although obesity is a known risk factor for coronary artery disease, its impact on the presentation, treatment, and outcome of patients with acute coronary syndromes (ACS) has not been well studied...
  17. ncbi Performance of a population-based cardiac risk stratification tool in Asian patients with chest pain
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157 1089, USA
    Acad Emerg Med 12:423-30. 2005
    ..Their validity in single-race populations has not been tested. The authors sought to compare the performance of a risk stratification tool between a mixed-race U.S. patient population and an Asian patient population...
  18. ncbi Treatment disparities in the care of patients with and without diabetes presenting with non-ST-segment elevation acute coronary syndromes
    Gerard X Brogan
    Department of Emergency Medicine, New York University School of Medicine North Shore Long Island Jewish Health System, Plainview, New York 11803, USA
    Diabetes Care 29:9-14. 2006
    ..The objective of this study was to characterize treatment patterns among patients with diabetes presenting with non-ST-segment elevation (NSTE) acute coronary syndromes (ACSs)...
  19. ncbi Prospective multicenter study of quantitative pretest probability assessment to exclude acute coronary syndrome for patients evaluated in emergency department chest pain units
    Alice M Mitchell
    Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28323-2861, USA
    Ann Emerg Med 47:447. 2006
    ....
  20. ncbi Lack of utility of telemetry monitoring for identification of cardiac death and life-threatening ventricular dysrhythmias in low-risk patients with chest pain
    Judd E Hollander
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104 4283, USA
    Ann Emerg Med 43:71-6. 2004
    ..We tested the hypothesis that monitoring admitted low-risk patients with chest pain for dysrhythmia is low yield (<1% detection of life-threatening dysrhythmias requiring treatment)...
  21. ncbi Meta-analysis of ischemia-modified albumin to rule out acute coronary syndromes in the emergency department
    Frank Peacock
    Department of Emergency Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:253-62. 2006
    ..4% and 97.1% and, for longer-term outcomes, were 89.2% and 94.5%, respectively. CONCLUSIONS: A negative TPT of a nondiagnostic electrocardiogram, negative troponin, and negative IMA has a high NPV for excluding ACS in the ED...
  22. ncbi Hospitals with and without percutaneous coronary intervention capability: considerations for treating acute coronary syndromes
    Judd E Hollander
    Department of Emergency Medicine, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104 4283, USA
    Am J Emerg Med 27:595-606. 2009
    ..Bivalirudin can be used in non-ST-segment elevation myocardial infarction patients who are managed invasively...
  23. ncbi Elevated serum cardiac markers predict coronary artery disease in patients with a history of heart failure who present with chest pain: insights from the i*trACS registry
    Jonathan Glauser
    Division of Medicine, Department of Emergency Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Congest Heart Fail 13:142-8. 2007
    ..5%) had CAD. A history of HF did not lessen the likelihood of CAD as evidenced by angiography and does not diminish the utility of cardiac markers in diagnosing acute coronary syndromes...
  24. ncbi Racial variations in treatment and outcomes of black and white patients with high-risk non-ST-elevation acute coronary syndromes: insights from CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Impleme
    Ali F Sonel
    Center for Health Equity Research and Promotion, Pittsburgh, PA, USA
    Circulation 111:1225-32. 2005
    ..It is unknown whether racial disparities exist for other treatments for non-ST-segment elevation acute coronary syndromes (NSTE ACS) and how different treatments affect outcomes...
  25. ncbi The usage patterns of cardiac bedside markers employing point-of-care testing for troponin in non-ST-segment elevation acute coronary syndrome: results from CRUSADE
    Kevin M Takakuwa
    Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Clin Cardiol 32:498-505. 2009
    ..We evaluated the use patterns of cardiac bedside markers or POC testing for troponin in patients with non-ST-segment elevation (NSTE) ACS...
  26. ncbi Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Eur Heart J 28:1079-84. 2007
    ..We compared the initial treatment and clinical outcomes of patients presenting with evolving MI (EMI) with those presenting with MI...
  27. ncbi Early treatment for non-ST-segment elevation acute coronary syndrome is associated with appropriate discharge care
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0769, USA
    Clin Cardiol 32:519-25. 2009
    ..Acute treatment is associated with improved in-hospital outcomes for patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS)...
  28. ncbi 2007 update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 51:591-606. 2008
    ....
  29. ncbi Antiplatelet therapy in acute coronary syndromes: the emergency physician's perspective
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19107, USA
    J Emerg Med 35:5-13. 2008
    ..For patients presenting to the emergency department with ACS, the benefits and risks of initiating clopidogrel or GP IIb/IIIa inhibitor therapy need to be considered on an individual basis...
  30. ncbi Weight-based dosing of enoxaparin in obese patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE initiative
    Sarah A Spinler
    Department of Pharmacy Practice and Pharmacy Administration, Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pharmacotherapy 29:631-8. 2009
    ..To evaluate how enoxaparin is dosed in contemporary clinical practice as a function of patients' total body weight (TBW) and body mass index (BMI), and to determine any association between dose and major bleeding...
  31. ncbi Is the initial diagnostic impression of "noncardiac chest pain" adequate to exclude cardiac disease?
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University, Winston Salem, NC 27157 1089, USA
    Ann Emerg Med 44:565-74. 2004
    ..In patients presenting to the emergency department (ED) with an initial diagnostic impression of noncardiac chest pain, we determine the 30-day incidence of adverse cardiac events and characteristics associated with those events...
  32. ncbi The Internet Tracking Registry of Acute Coronary Syndromes (i*trACS): a multicenter registry of patients with suspicion of acute coronary syndromes reported using the standardized reporting guidelines for emergency department chest pain studies
    Christopher J Lindsell
    Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 48:666-77, 677.e1-9. 2006
    ..We describe the methods for data collection and the ED population enrolled in a multicenter registry of patients with chest pain...
  33. ncbi Does timing matter? Upstream or downstream administration of antiplatelet therapy
    David Slattery
    Department of Emergency Medicine, University of Nevada School of Medicine, Las Vegas, NV 89106, USA
    Am J Emerg Med 27:348-61. 2009
    ....
  34. ncbi Influence of sex on the out-of-hospital management of chest pain
    Zachary F Meisel
    Robert Wood Johnson Foundation Clinical Scholars Program, Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Acad Emerg Med 17:80-7. 2010
    ..Out-of-hospital (OOH) care for chest pain is protocol-driven and may be less likely to demonstrate differences between men and women...
  35. ncbi Clevidipine for severe hypertension in acute heart failure: a VELOCITY trial analysis
    Frank W Peacock
    Department of Emergency Medicine, Cleveland Clinic, Cleveland, OH 44195 0001, USA
    Congest Heart Fail 16:55-9. 2010
    ..Clevidipine safely decreases SBP in AHF and does not cause unexpected hypotension. The results of this post hoc subgroup analysis suggest that clevidipine is safe, well tolerated, and efficacious in AHF patients with hypertension...
  36. ncbi Utilization and impact of pre-hospital electrocardiograms for patients with acute ST-segment elevation myocardial infarction: data from the NCDR (National Cardiovascular Data Registry) ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Re
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis Medical Center, Sacramento, CA 95661, USA
    J Am Coll Cardiol 53:161-6. 2009
    ..This study sought to determine the association of pre-hospital electrocardiograms (ECGs) and the timing of reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI)...
  37. ncbi Pretest probability assessment derived from attribute matching
    Jeffrey A Kline
    Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC, USA
    BMC Med Inform Decis Mak 5:26. 2005
    ..This report compares a novel attribute-matching method to generate a PTP for acute coronary syndrome (ACS). We compare the new method with a validated logistic regression equation (LRE)...
  38. ncbi The medical management of acute coronary syndromes and potential roles for new antithrombotic agents
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19107, USA
    J Emerg Med 34:417-28. 2008
    ..These data underscore the promise of new antithrombotic agents to improve outcomes in acute coronary syndrome (ACS) patients being medically managed...
  39. ncbi Standardized reporting guidelines for studies evaluating risk stratification of emergency department patients with potential acute coronary syndromes
    Judd E Hollander
    University of Pennsylvania, Philadelphia, PA, USA
    Ann Emerg Med 44:589-98. 2004
  40. ncbi Prognostic value of symptoms during a normal or nonspecific electrocardiogram in emergency department patients with potential acute coronary syndrome
    Maureen Chase
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Acad Emerg Med 13:1034-9. 2006
    ..The authors hypothesized that patients with a normal or nonspecific ECG during symptoms have a lower risk for ACS than do those who are asymptomatic...
  41. ncbi The association between emergency department crowding and adverse cardiovascular outcomes in patients with chest pain
    Jesse M Pines
    Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Acad Emerg Med 16:617-25. 2009
    ..The authors examined whether ED crowding was associated with adverse cardiovascular outcomes in patients with chest pain syndromes (chest pain or related complaints of possible cardiac origin)...
  42. ncbi Multicenter validation of the Philadelphia EMS admission rule (PEAR) to predict hospital admission in adult patients using out-of-hospital data
    Zachary F Meisel
    The Robert Wood Johnson Foundation Clinical Scholars Program, Leonard Davis Institute of Health Economics, and the Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Acad Emerg Med 16:519-25. 2009
    ..The objective was to validate a previously derived prediction rule for hospital admission using routinely collected out-of-hospital information...
  43. ncbi Derivation and internal validation of a rule to predict hospital admission in prehospital patients
    Zachary F Meisel
    Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Prehosp Emerg Care 12:314-9. 2008
    ....
  44. ncbi Discordant cardiac biomarkers: frequency and outcomes in emergency department patients with chest pain
    Alan B Storrow
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4700, USA
    Ann Emerg Med 48:660-5. 2006
    ....
  45. ncbi The role of cardiac risk factor burden in diagnosing acute coronary syndromes in the emergency department setting
    Jin H Han
    Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, TN 37232 4700, USA
    Ann Emerg Med 49:145-52, 152.e1. 2007
    ..We seek to determine whether cardiac risk factor burden (defined as the number of conventional cardiac risk factors present) is useful for the diagnosis of acute coronary syndromes in the emergency department (ED) setting...
  46. ncbi Insurance status and the treatment of myocardial infarction at academic centers
    Brian C Hiestand
    Department of Emergency Medicine, The Ohio State University, 149 Means Hall, 1654 Upham Drive, Columbus, OH 43210 1270, USA
    Acad Emerg Med 11:343-8. 2004
    ..Numerous studies have documented treatment disparities in patients with acute coronary syndromes based on race and gender. Other causes for treatment disparities may exist...
  47. ncbi Intracranial pathology in elders with blunt head trauma
    Niels K Rathlev
    Department of Emergency Medicine, Boston Medical Center, Boston, MA 02118, USA
    Acad Emerg Med 13:302-7. 2006
    ....
  48. ncbi A study of the workforce in emergency medicine: 1999
    John C Moorhead
    Department of Emergency Medicine, Oregon Health Science University, Portland, OR, USA
    Ann Emerg Med 40:3-15. 2002
    ..02). The total number of emergency physicians remained the same over the 2-year period, whereas the number of FTEs per institution increased from 5.11 to 5.35. The physician/FTE ratio remained unchanged...
  49. ncbi The impact of race on the acute management of chest pain
    Arvind Venkat
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Acad Emerg Med 10:1199-208. 2003
    ..40 to 0.68 and OR, 0.68; 95% CI = 0.47 to 0.99). CONCLUSIONS: Racial disparities in acute chest pain management extend beyond cardiac catheterization. Poor compliance with recommended treatments for ACS may be an explanation...
  50. ncbi Seizures as a cause of altered mental status
    David E Slattery
    Department of Emergency Medicine, University of Nevada School of Medicine, 901 Rancho Lane, Suite 135, Las Vegas, NV 89106, USA
    Emerg Med Clin North Am 28:517-34. 2010
    ..The article focuses on those agents that should prompt the emergency physician to initiate unique therapy to abate the seizure and correct the underlying cause...
  51. ncbi Cardiac troponins
    John Sarko
    Department of Emergency Medicine, Maricopa Medical Center, Phoenix, Arizona 85008, USA
    J Emerg Med 23:57-65. 2002
    ..This review discusses the cardiac troponins, their biochemistry, the assays for them currently available, and their roles in the evaluation of cardiac disease in the Emergency Department (ED)...
  52. ncbi Interrater reliability of criteria used in assessing blunt head injury patients for intracranial injuries
    Judd E Hollander
    Departments of Emergency Medicine, University of Pennsylvania School of Medicine, Ravdin Building Ground Floor, 3400 Spruce Street, Philadelphia, PA 19104 4283, USA
    Acad Emerg Med 10:830-5. 2003
    ..To determine the interrater reliability of potential predictor variables that may be used to construct a clinical decision rule for emergency computed tomography of the head in blunt head injury victims...
  53. ncbi Heliox in airway management
    Jane M McGarvey
    Department of Emergency Medicine, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Emerg Med Clin North Am 26:905-20, viii. 2008
    ....
  54. ncbi A prospective multicenter study of patient factors associated with hospital admission from the emergency department among children with acute asthma
    Charles V Pollack
    Department of Emergency Medicine, Pennsylvania Hospital, 800 Spruce St, Philadelphia, PA 19107, USA
    Arch Pediatr Adolesc Med 156:934-40. 2002
    ....
  55. ncbi Changing the model of care for patients with acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 146:605-12. 2003
    ..The shifting model of care for ACS therefore suggests that quality improvement and monitoring of adherence to practice guidelines should be considered components of optimal clinical practice...
  56. ncbi Influence of clinical trial enrollment on the quality of care and outcomes for patients with non-ST-segment elevation acute coronary syndromes
    David E Kandzari
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 149:474-81. 2005
    ....
  57. ncbi Influence of timing of troponin elevation on clinical outcomes and use of evidence-based therapies for patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Ann Emerg Med 45:355-62. 2005
    ....
  58. ncbi Patterns of transfer for patients with non-ST-segment elevation acute coronary syndrome from community to tertiary care hospitals
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 156:185-92. 2008
    ....
  59. ncbi Use of and inhospital outcomes after early clopidogrel therapy in patients not undergoing an early invasive strategy for treatment of non-ST-segment elevation myocardial infarction: results from Can Rapid risk stratification of Unstable angina patients Su
    Deepu Alexander
    Division of Cardiovascular Medicine, State University of New York, Stony Brook School of Medicine, Stony Brook, NY 11794, USA
    Am Heart J 156:606-12. 2008
    ..We sought to determine patterns of early (<24 hours of arrival) clopidogrel use and its association with clinical outcomes in patients with NSTEMI not undergoing early percutaneous intervention (PCI)...
  60. ncbi The evolution of thrombolytic therapy and adjunctive antithrombotic regimens in acute ST-segment elevation myocardial infarction
    Marc Cohen
    Division of Cardiology, Newark Beth Israel Medical Center, Cardiac Cath Lav Administration, New Jersey 07112, USA
    Am J Emerg Med 22:14-23. 2004
    ..More recent data can be interpreted as showing that regimens that are simpler and easier to administer are also clinically superior. This article reviews pharmacologic advances and evaluates the evidence for their use in EDs...
  61. ncbi Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: observations from the National Registry of Myocardial Infarction 4
    Eric D Peterson
    Duke Clinical Research Institute, 2400 Pratt Street, Room 7009, Durham, NC 27705, USA
    J Am Coll Cardiol 42:45-53. 2003
    ..We sought to identify patient and hospital features associated with early glycoprotein (GP) IIb/IIIa inhibitor therapy for non-ST-elevation (NSTE) myocardial infarction (MI) and to relate this treatment to in-hospital outcomes...
  62. ncbi Can electrocardiographic criteria predict adverse cardiac events and positive cardiac markers?
    Andra L Blomkalns
    University of Cincinnati, Cincinnati, OH45267 0769, USA
    Acad Emerg Med 10:205-10. 2003
    ..The authors hypothesized that specific ECG findings, other than those previously identified in higher-risk populations, would be predictive of cardiac outcomes and positive cardiac markers...
  63. ncbi Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative
    James W Hoekstra
    Ohio State University, Columbus, OH 43210, USA
    Acad Emerg Med 9:1146-55. 2002
    ..It is the intent of CRUSADE to improve patient care in the ED by tracking and encouraging compliance with evidence-based guidelines for the evaluation and management of NSTE ACS...
  64. ncbi Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgen
    Harvey D White
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    J Am Coll Cardiol 51:1734-41. 2008
    ..The aim of this study was to compare outcomes in patients receiving consistent unfractionated heparin (UFH)/enoxaparin (ENOX) therapy and in those switched at randomization to bivalirudin monotherapy...
  65. ncbi Practical implementation of the guidelines for unstable angina/non-ST-segment elevation myocardial infarction in the emergency department: a scientific statement from the American Heart Association Council on Clinical Cardiology (Subcommittee on Acute Car
    W Brian Gibler
    Circulation 111:2699-710. 2005
    ..Despite publication of the guidelines several years ago, many patients with UA/NSTEMI still do not receive guidelines-indicated therapy...
  66. ncbi Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
    Frederick Feit
    Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, New York, USA
    J Am Coll Cardiol 51:1645-52. 2008
    ..We sought to evaluate clinical outcomes of patients with diabetes mellitus in the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial, overall and by treatment arm...
  67. ncbi Practical implementation of the Guidelines for Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction in the emergency department
    W Brian Gibler
    University of Cincinnati College of Medicine, USA
    Ann Emerg Med 46:185-97. 2005
    ..Despite publication of the guidelines several years ago, many patients with UA/NSTEMI still do not receive guidelines-indicated therapy...
  68. ncbi The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 152:648-60. 2006
    ..We sought to assess the influence of emergency department (ED) structure and care processes on adherence to practice guidelines for the treatment of patients with non-ST-segment elevation acute coronary syndromes...
  69. ncbi Prevalence, predictors, and outcomes of patients with non-ST-segment elevation myocardial infarction and insignificant coronary artery disease: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early
    Manesh R Patel
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 152:641-7. 2006
    ..We sought to determine the prevalence, predictors, and outcomes of patients with NSTEMI and insignificant CAD...
  70. ncbi Door-to-ECG time in patients with chest pain presenting to the ED
    Deborah B Diercks
    Division of Emergency Medicine, University of California, Davis Medical Center, Sacramento, 95817, USA
    Am J Emerg Med 24:1-7. 2006
    ..To describe time to electrocardiogram (ECG) acquisition, identify factors associated with timely acquisition, and evaluate the influence of time to ECG on adverse clinical outcomes...
  71. ncbi Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery
    Rajendra H Mehta
    Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 48:281-6. 2006
    ....
  72. ncbi Relation between hospital specialization with primary percutaneous coronary intervention and clinical outcomes in ST-segment elevation myocardial infarction: National Registry of Myocardial Infarction-4 analysis
    Brahmajee K Nallamothu
    Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
    Circulation 113:222-9. 2006
    ..CONCLUSIONS: Greater specialization with PPCI is associated with lower in-hospital mortality and shorter door-to-balloon times in STEMI patients treated with PPCI...
  73. ncbi Impact of congestive heart failure in patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 97:1707-12. 2006
    ..Further study is needed to determine the causes of these treatment differences and the optimal therapeutic approach for patients with NSTE ACS and concomitant CHF...
  74. ncbi Low-molecular-weight heparin compared with unfractionated heparin for patients with non-ST-segment elevation acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE initiative
    Kanwar P Singh
    Division of Cardiology and Duke Clinical Research Institute, Durham, NC 27705, USA
    J Thromb Thrombolysis 21:211-20. 2006
    ....
  75. ncbi Association between hospital process performance and outcomes among patients with acute coronary syndromes
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    JAMA 295:1912-20. 2006
    ..Selected care processes are increasingly being used to measure hospital quality; however, data regarding the association between hospital process performance and outcomes are limited...
  76. ncbi Frequency and consequences of recording an electrocardiogram >10 minutes after arrival in an emergency room in non-ST-segment elevation acute coronary syndromes (from the CRUSADE Initiative)
    Deborah B Diercks
    University of California Davis Medical Center, Sacramento, California, USA
    Am J Cardiol 97:437-42. 2006
    ..Women were significantly more likely than men to have delayed ECG acquisition. Emergency departments should focus on decreasing the time to initial ECG acquisition to improve treatment of acute coronary syndrome in this group...
  77. ncbi A subgroup analysis of the impact of prerandomization antithrombin therapy on outcomes in the SYNERGY trial: enoxaparin versus unfractionated heparin in non-ST-segment elevation acute coronary syndromes
    Marc Cohen
    HEART Hospital of New Jersey, Newark Beth Israel Medical Center, Newark, New Jersey 07112, USA
    J Am Coll Cardiol 48:1346-54. 2006
    ....
  78. ncbi Moving from evidence to practice in the care of patients who have acute coronary syndrome
    Kelly L Miller
    Division of Cardiology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Cardiol Clin 24:87-102. 2006
    ..Lessons learned from previous and ongoing quality improvement initiatives will provide the tools needed to ensure that widespread adoption of guideline-based therapy is complete...
  79. ncbi Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Intern Med 166:2027-34. 2006
    ..We sought to determine recent trends in adherence to guideline-based therapies for NSTE ACS...
  80. ncbi Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative
    Karen P Alexander
    Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 46:1479-87. 2005
    ..This study evaluated the impact of age on care and outcomes for non-ST-segment elevation acute coronary syndromes (NSTE ACS)...
  81. ncbi Paradoxical use of invasive cardiac procedures for patients with non-ST segment elevation myocardial infarction: an international perspective from the CRUSADE Initiative and the Canadian ACS Registries I and II
    Mohammad I Zia
    Canadian Heart Research Centre, Toronto, Canada
    Can J Cardiol 23:1073-9. 2007
    ..Practice guidelines support an early invasive strategy in patients with non-ST segment elevation acute coronary syndromes, particularly in those at higher risk...
  82. ncbi The impact of for-profit hospital status on the care and outcomes of patients with non-ST-segment elevation myocardial infarction: results from the CRUSADE Initiative
    Bimal R Shah
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 50:1462-8. 2007
    ..We sought to determine whether for-profit status influenced hospitals' care or outcomes among non-ST-segment elevation myocardial infarction (NSTEMI) patients...
  83. ncbi Enoxaparin dosing and associated risk of in-hospital bleeding and death in patients with non ST-segment elevation acute coronary syndromes
    Nancy M Allen LaPointe
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 167:1539-44. 2007
    ..The extent to which bleeding risk is attributable to excess dosing of enoxaparin is unclear...
  84. ncbi Prolonged emergency department stays of non-ST-segment-elevation myocardial infarction patients are associated with worse adherence to the American College of Cardiology/American Heart Association guidelines for management and increased adverse events
    Deborah B Diercks
    University of California, Davis, School of Medicine, Sacramento, CA, USA
    Ann Emerg Med 50:489-96. 2007
    ..We hypothesized that patients with non-ST-segment-elevation myocardial infarction who have ED stays of greater than 8 hours may have lower quality of care and worse outcomes...
  85. ncbi Relationship between risk stratification by cardiac troponin level and adherence to guidelines for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 165:1870-6. 2005
    ..The threshold of troponin elevation that stimulates changes in clinical decision making for patients with non-ST-segment elevation acute coronary syndromes (NSTE ACSs) has not been previously evaluated...
  86. ncbi Patterns of aspirin dosing in non-ST-elevation acute coronary syndromes in the CRUSADE Quality Improvement Initiative
    Sumit Tickoo
    Bridgeport Hospital, Bridgeport, Connecticut, USA
    Am J Cardiol 99:1496-9. 2007
    ....
  87. ncbi Timing of glycoprotein IIb/IIIa inhibitor use and outcomes among patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (results from CRUSADE)
    Pierluigi Tricoci
    Division of Cardiology, and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am J Cardiol 99:1389-93. 2007
    ..In conclusion, in this observational analysis, overall ischemic outcomes were similar between the 2 groups, but clinical trials are needed to solve the controversy over optional timing of GP IIb/IIIa inhibitor use...
  88. ncbi Optimal timing of intervention in non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) Regist
    Jason W Ryan
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Circulation 112:3049-57. 2005
    ..Using weekend status as an instrumental variable, we found no significant benefit to early catheterization, although we could not exclude an important risk reduction, particularly for catheterization within 12 hours of presentation...
  89. ncbi Clopidogrel to treat patients with non-ST-segment elevation acute coronary syndromes after hospital discharge
    Pierluigi Tricoci
    Division of Cardiology, Duke University School of Medicine, and Duke Clinical Research Institute, Durham, NC, USA
    Arch Intern Med 166:806-11. 2006
    ....