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Genomes and Genes | Bogdan PolevodaSummaryAffiliation: University of Rochester Country: USA Publications
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A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substratesBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA
BMC Proc 3:S2. 2009..ABSTRACT : We have introduced a consistent nomenclature for the various subunits of the NatA-NatE N-terminal acetyltransferases from yeast, humans and other eukaryotes...
Methylation of proteins involved in translationBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, USA
Mol Microbiol 65:590-606. 2007..Differential methylation of specific RPs and TFs in a number of organisms at different physiological states indicates that this modification may play a regulatory role...
The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2pBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, USA
J Biol Chem 281:2562-71. 2006..Most interestingly, the mtq2-Delta was significantly more resistant to the anti-microtubule drugs thiabendazole and benomyl, suggesting that Mtq2p may also methylate certain microtubule-related proteins...
Composition and function of the eukaryotic N-terminal acetyltransferase subunitsBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Biochem Biophys Res Commun 308:1-11. 2003..Thus, the vertebrate NATs remain to be definitively identified, and, furthermore, it remains to be seen if any of the yeast NATs contribute to other functions...
Properties of Nat4, an N(alpha)-acetyltransferase of Saccharomyces cerevisiae that modifies N termini of histones H2A and H4Bogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA
Mol Cell Biol 29:2913-24. 2009..Thus, N-terminal serine acetylation of histone H4 may be a part of an essential charge patch first described for the histone H2A.Z variant in Tetrahymena species...
Yeast N(alpha)-terminal acetyltransferases are associated with ribosomesBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, USA
J Cell Biochem 103:492-508. 2008..Moreover, Ard1p copurifies with Rpl35p-TAP. We suggest that these two ribosomal proteins, which are in close proximity to the ribosomal exit tunnel, may play a role in NatA attachment to the ribosome...
Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosinBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Biol Chem 278:30686-97. 2003..Furthermore, unacetylated actin and certain N-terminally altered actins have comparable defective properties in vitro, particularly actin-activated ATPase activity and sliding velocity...
N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteinsBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
J Mol Biol 325:595-622. 2003..Overall patterns of N-terminal acetylated proteins and the orthologous genes possibly encoding NATs suggest that yeast and higher eukaryotes have the same systems for N-terminal acetylation...
Phenotypes of yeast mutants lacking the mitochondrial protein Pet20pBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, USA
Yeast 23:127-39. 2006..It is also possible that Pet20p may constitute a non-catalytic subunit of an uncharacterized mitochondrial complex or serve as a transporter or a coupling factor...
The diversity of acetylated proteinsBogdan Polevoda
Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Genome Biol 3:reviews0006. 2002....
N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasomeYayoi Kimura
Kihara Institute for Biological Research Graduate School of Integrated Science, Yokohama City University, Maioka 641 12, Totsuka, Yokohama, Japan
Arch Biochem Biophys 409:341-8. 2003..These characteristics were different from those of the 20S proteasome: the chymotrypsin-like activity and accumulation level of 20S proteasome were appreciably higher from the nat1 deletion mutant than from the normal strain...
