D R Pierce

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi Are oxidative mechanisms primary in ethanol induced Purkinje neuron death of the neonatal rat?
    Dwight R Pierce
    Department of Health Sciences, University of Central Arkansas, Conway, AR 72035, USA
    Neurosci Lett 400:130-4. 2006
  2. ncbi Developmental alterations in olivary climbing fiber distribution following postnatal ethanol exposure in the rat
    D R Pierce
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 W Markham Street, 522 3 Little Rock, AR 72205 7199, USA
    Neuroscience 169:1438-48. 2010
  3. ncbi Olivary climbing fiber alterations in PN40 rat cerebellum following postnatal ethanol exposure
    Dwight R Pierce
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, 522 3, Little Rock, AR 72205 7199, USA
    Brain Res 1378:54-65. 2011
  4. ncbi Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat
    K E Light
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA
    Neuroscience 114:327-37. 2002
  5. ncbi Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression
    Yun Ge
    Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA
    Toxicol Lett 150:325-34. 2004
  6. ncbi Altered expression of Bcl2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9
    Yun Ge
    Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Brain Res Mol Brain Res 129:124-34. 2004

Detail Information

Publications6

  1. ncbi Are oxidative mechanisms primary in ethanol induced Purkinje neuron death of the neonatal rat?
    Dwight R Pierce
    Department of Health Sciences, University of Central Arkansas, Conway, AR 72035, USA
    Neurosci Lett 400:130-4. 2006
    ..These in vivo analyses do not support a robust oxidative mechanism involving the production of reactive nitrogen species as a significant means of Purkinje cell neurodegeneration...
  2. ncbi Developmental alterations in olivary climbing fiber distribution following postnatal ethanol exposure in the rat
    D R Pierce
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 W Markham Street, 522 3 Little Rock, AR 72205 7199, USA
    Neuroscience 169:1438-48. 2010
    ..These alterations in the synaptic integrity were both dose dependent and temporally dependent...
  3. ncbi Olivary climbing fiber alterations in PN40 rat cerebellum following postnatal ethanol exposure
    Dwight R Pierce
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, 522 3, Little Rock, AR 72205 7199, USA
    Brain Res 1378:54-65. 2011
    ....
  4. ncbi Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat
    K E Light
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA
    Neuroscience 114:327-37. 2002
    ..Furthermore, the initiation of apoptosis by ethanol is consistent with ethanol-induced interruptions of Purkinje cell neurotrophic support leading to activation of the mitochondrial pathway of apoptosis...
  5. ncbi Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression
    Yun Ge
    Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA
    Toxicol Lett 150:325-34. 2004
    ....
  6. ncbi Altered expression of Bcl2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9
    Yun Ge
    Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Brain Res Mol Brain Res 129:124-34. 2004
    ..These results are in agreement with and provide further support for our hypothesis that ethanol interrupts the active suppression of apoptosis that is a crucial feature of Purkinje cell vulnerability during this time period...