Larisa Pereboeva

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor
    Svetlana Komarova
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 2172, USA
    J Ovarian Res 3:12. 2010
  2. ncbi A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294 2172, USA
    Clin Cancer Res 13:2777-83. 2007
  3. ncbi A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, Obstetrics and Gynecology, The University of Alabama at Birmingham, 901 19th Street South, BMR2 508, Birmingham, AL 35294 2180, USA
    Clin Cancer Res 14:3582-8. 2008
  4. ncbi Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Biochem Biophys Res Commun 335:205-14. 2005
  5. ncbi Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses
    Svetlana Komarova
    Division of Human Gene Therapy, Department of Medicine, Gene Therapy Center, University of Alabama at Birmingham, 901 19th Street South, BMR2-572, Birmingham, AL 35294-3300, USA
    Mol Cancer Ther 5:755-66. 2006
  6. ncbi An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles
    Vaibhav Saini
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Small 4:262-9. 2008
  7. ncbi Cellular vehicles for cancer gene therapy: current status and future potential
    Larisa Pereboeva
    Division of Human Gene Therapy, Department of Medicine, The Gene Therapy Center, BMRII 572, University of Alabama at Birmingham, 901 19th Street S, Birmingham, AL 35294, USA
    BioDrugs 18:361-85. 2004
  8. ncbi Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors
    Larisa Pereboeva
    Division of Human Gene Therapy, Department of Medicine, The Gene Therapy Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Virus Res 105:35-46. 2004
  9. ncbi Functional Sindbis virus replicative complexes are formed at the plasma membrane
    Elena I Frolova
    Department of Microbiology, University of Alabama, Birmingham, AL 35294 2170, USA
    J Virol 84:11679-95. 2010

Collaborators

Detail Information

Publications9

  1. ncbi Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor
    Svetlana Komarova
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 2172, USA
    J Ovarian Res 3:12. 2010
    ..We investigated the feasibility of enhancing MSC tumor targeting by expressing an artificial tumor-binding receptor on the MSC surface...
  2. ncbi A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294 2172, USA
    Clin Cancer Res 13:2777-83. 2007
    ..We hypothesized that combined use of unique chimeric fibers in the context of novel mosaic adenovirus vectors would enhance infectivity via non-CAR pathways in ovarian cancer cells...
  3. ncbi A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, Obstetrics and Gynecology, The University of Alabama at Birmingham, 901 19th Street South, BMR2 508, Birmingham, AL 35294 2180, USA
    Clin Cancer Res 14:3582-8. 2008
    ..The purpose of this study was to explore the therapeutic utility of a mesothelin promoter-based CRAd in a murine model of ovarian cancer, using noninvasive in vivo imaging...
  4. ncbi Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway
    Yuko Tsuruta
    Division of Human Gene Therapy, Department of Medicine, and the Gene Therapy Center, The University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Biochem Biophys Res Commun 335:205-14. 2005
    ..Thus, we have developed a new type of Ad5 vector with expanded tropism, possessing fibers from Ad5 and reovirus, that exhibits enhanced infectivity via CAR-independent pathway(s)...
  5. ncbi Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses
    Svetlana Komarova
    Division of Human Gene Therapy, Department of Medicine, Gene Therapy Center, University of Alabama at Birmingham, 901 19th Street South, BMR2-572, Birmingham, AL 35294-3300, USA
    Mol Cancer Ther 5:755-66. 2006
    ..These data show that MPCs can serve as intermediate carriers for replicative adenoviruses and suggest that the natural homing properties of specific cell types can be used for targeted delivery of these virions...
  6. ncbi An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles
    Vaibhav Saini
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Small 4:262-9. 2008
    ..This opens the possibility of using Ad vectors for targeted NP delivery, thereby providing a new type of combinatorial approach for the treatment of diseases that involves both nanotechnology and gene therapy...
  7. ncbi Cellular vehicles for cancer gene therapy: current status and future potential
    Larisa Pereboeva
    Division of Human Gene Therapy, Department of Medicine, The Gene Therapy Center, BMRII 572, University of Alabama at Birmingham, 901 19th Street S, Birmingham, AL 35294, USA
    BioDrugs 18:361-85. 2004
    ..There is hope that advances in related scientific fields will promote the utilization of cells as powerful and versatile vehicles for cancer gene therapy...
  8. ncbi Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors
    Larisa Pereboeva
    Division of Human Gene Therapy, Department of Medicine, The Gene Therapy Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Virus Res 105:35-46. 2004
    ..Therefore, the mosaic setting will allow more flexibility in Ad retargeting approaches...
  9. ncbi Functional Sindbis virus replicative complexes are formed at the plasma membrane
    Elena I Frolova
    Department of Microbiology, University of Alabama, Birmingham, AL 35294 2170, USA
    J Virol 84:11679-95. 2010
    ....