Research Topics
| Bruce PenningtonSummaryAffiliation: University of Denver Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Early reading development in children at family risk for dyslexiaB F Pennington
Department of Psychology, University of Denver, CO 80208, USA
Child Dev 72:816-33. 2001..Finally, later RD could be predicted with moderate accuracy at age 5 years, with the strongest predictor being letter-name knowledge...- Toward a new neuropsychological model of attention-deficit/hyperactivity disorder: subtypes and multiple deficitsBruce F Pennington
Department of Psychology, University of Denver, Denver, CO 80210-4638, USA
Biol Psychiatry 57:1221-3. 2005 - How neuropsychology informs our understanding of developmental disordersBruce F Pennington
Department of Psychology, University of Denver, 2155 S Race Street, Denver, Colorado 80208 4403, USA
J Child Psychol Psychiatry 50:72-8. 2009.... - The neuropsychology of Down syndrome: evidence for hippocampal dysfunctionBruce F Pennington
Department of Psychology, University of Denver CO 80208, USA
Child Dev 74:75-93. 2003..It is interesting that these results are similar to what has been found in a mouse model of DS. Such a model will make it easier to understand the neurobiological mechanisms that lead to the development of hippocampal dysfunction in DS... - Heritability of high reading ability and its interaction with parental educationAngela Friend
Department of Psychology, University of Colorado at Boulder, Boulder, CO 80309, USA
Behav Genet 39:427-36. 2009..This result provides a coherent account when considered alongside results of previous research showing that heritability for low reading ability decreased with lower levels of parental education... - Sensory processing, reading, IQ, and attentionJacqueline Hulslander
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
J Exp Child Psychol 88:274-95. 2004.... - Gene x Environment interactions in speech sound disorder predict language and preliteracy outcomesLauren M McGrath
University of Denver, Department of Psychology, Frontier Hall, 2155 S Race Street, Denver, CO 80209, USA
Dev Psychopathol 19:1047-72. 2007..The direction of these interactions and possible interpretations are explored in the discussion... - Breakthroughs in the search for dyslexia candidate genesLauren M McGrath
University of Denver, Department of Psychology, Frontier Hall, 2155 S Race St, Denver, CO 80208, USA
Trends Mol Med 12:333-41. 2006..When causal variants are identified, they will need to be considered within a multifactorial framework, which is likely to involve gene-gene and gene-environment interactions, to make accurate predictions of diagnostic status... - From single to multiple deficit models of developmental disordersBruce F Pennington
Department of Psychology, University of Denver, 2155 S Race St, Denver, CO 80208, USA
Cognition 101:385-413. 2006..It describes how this model evolved out of our attempts to understand two comorbidities, those between dyslexia and attention deficit hyperactivity disorder (ADHD) and between dyslexia and speech sound disorder (SSD)... - Processing speed deficits in attention deficit/hyperactivity disorder and reading disabilityMichelle A Shanahan
Department of Psychology, University of Denver, Denver, Colorado, USA
J Abnorm Child Psychol 34:585-602. 2006.... - Deficient implicit phonological representations in children with dyslexiaRichard Boada
Department of Psychology, University of Denver, Denver, CO 80208, USA
J Exp Child Psychol 95:153-93. 2006..Results provide strong support for less mature implicit phonological representations in children with dyslexia... - The perception of animacy in young children with autismM D Rutherford
McMaster University, Hamilton, Ontario L8S 4K1, Canada
J Autism Dev Disord 36:983-92. 2006..These results are discussed in terms of the social orienting theory of autism, and the possibility that animacy perception might be preserved in autism, even if it is not used automatically... - Executive function in preschoolers with autism: evidence consistent with a secondary deficitBenjamin E Yerys
Department of Psychology, University of Denver, 2155 S Race Street, Denver, CO 80208, USA
J Autism Dev Disord 37:1068-79. 2007..Alternative hypotheses are also considered... - Neuropsychology and genetics of speech, language, and literacy disordersRobin L Peterson
Department of Psychology, University of Denver, 2155 South Race Street, Denver, CO 80208, USA
Pediatr Clin North Am 54:543-61, vii. 2007..Research across levels of analysis is progressing rapidly to promote understanding not only of each disorder by itself but also of the relationships of the three disorders to each other... - Modeling rater disagreement for ADHD: are parents or teachers biased?Christie A Hartman
Department of Psychiatry, University of Colorado at Denver and Health Sciences Center, 4200 East 9th Ave, Box C 268 35, Denver, CO 80262, USA
J Abnorm Child Psychol 35:536-42. 2007.... - Understanding comorbidity: a twin study of reading disability and attention-deficit/hyperactivity disorderErik G Willcutt
University of Colorado at Boulder, Boulder, Colorado 80309, USA
Am J Med Genet B Neuropsychiatr Genet 144:709-14. 2007.... - Impairments in phonological processing and nonverbal intellectual function in parents of children with autismGwen L Schmidt
Colorado State University, Fort Collins, CO, USA
J Clin Exp Neuropsychol 30:557-67. 2008..Our finding of nonword repetition difficulties, along with others' previous findings for nonword reading in autism families, suggests that problems in phonological processing might be characteristic of the broad autism phenotype... - Do motivational incentives reduce the inhibition deficit in ADHD?Michelle A Shanahan
Department of Psychology, University of Denver, CO 80208 0001, USA
Dev Neuropsychol 33:137-59. 2008..Hence, as predicted by the inhibition theory, children with ADHD performed worse than controls irrespective of incentives... - Testing for neuropsychological endophenotypes in siblings discordant for attention-deficit/hyperactivity disorderL Cinnamon Bidwell
Department of Psychology, University of Colorado, Boulder, Colorado, USA
Biol Psychiatry 62:991-8. 2007..Neurocognitive deficits associated with attention-deficit/hyperactivity disorder (ADHD) might be useful intermediate endophenotypes for determining specific genetic pathways that contribute to ADHD... - Test of alternative hypotheses explaining the comorbidity between attention-deficit/hyperactivity disorder and conduct disorderSoo Hyun Rhee
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
J Abnorm Child Psychol 36:29-40. 2008..The results suggest that correlated risk factors are a better explanation for the comorbidity between ADHD and CD than a third, independent ADHD+CD subtype... - Brain structure correlates of component reading processes: implications for reading disabilityErin Phinney
Department of Psychology, University of Denver, Denver, CO 80208, USA
Cortex 43:777-91. 2007.... - Children with comorbid speech sound disorder and specific language impairment are at increased risk for attention-deficit/hyperactivity disorderLauren M McGrath
Department of Psychology, University of Denver, Frontier Hall 2155 S Race St, Denver, CO 80209, USA
J Abnorm Child Psychol 36:151-63. 2008..In addition, an unexpected interaction emerged such that children with SLI and normalized-SSD had significantly higher ADHD inattentive ratings than the other subgroups. A proposed explanation for this interaction is discussed... - Spatial cognition in autism spectrum disorders: superior, impaired, or just intact?Jamie O Edgin
University of Denver, CO, USA
J Autism Dev Disord 35:729-45. 2005..There was no evidence for impairments in EF or in processing global/local information, therefore contradicting these two theories. The implications of these results for these two theories are discussed... - DCDC2 is associated with reading disability and modulates neuronal development in the brainHaiying Meng
Department of Pediatrics, Yale Child Health Research Center, Yale University School of Medicine, New Haven, CT 06520, USA
Proc Natl Acad Sci U S A 102:17053-8. 2005..The statistical and functional studies are complementary and are consistent with the latest clinical imaging data for RD. Thus, we propose that DCDC2 is a candidate gene for RD... - Collaborative analysis of DRD4 and DAT genotypes in population-defined ADHD subtypesRichard D Todd
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Child Psychol Psychiatry 46:1067-73. 2005..The goal of the current study is to test whether population-based ADHD subtypes defined by latent class analysis help resolve issues of variable findings across individual gene association studies... - Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1Clyde Francks
Wellcome Trust Centre for Human Genetics, University of Oxford, UK
Psychiatr Genet 12:35-41. 2002..Our study outlines the approach necessary for the identification of genetic variants causing dyslexia susceptibility in an epidemiological population of dyslexics... - Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention-deficit/hyperactivity disorderErik G Willcutt
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
Am J Med Genet 114:260-8. 2002.... - Interrelations among social-cognitive skills in young children with autismMalinda Carpenter
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
J Autism Dev Disord 32:91-106. 2002..Implications for theories of social-cognitive and language development are discussed... - Eye movement abnormality suggestive of a spatial working memory deficit is present in parents of autistic probandsDianne L Koczat
Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
J Autism Dev Disord 32:513-8. 2002..These deficits deserve further evaluation as a potential endophenotypic marker for genetic risk for autism... - Etiology of the comorbidity between RD and ADHD: exploration of the non-random mating hypothesisMelanie C Friedman
Department of Psychology, University of Denver, Denver, Colorado 80208, USA
Am J Med Genet B Neuropsychiatr Genet 120:109-15. 2003..There was little evidence to support that non-random mating also contributes to this comorbidity in the present sample... - Pre-literacy skills of subgroups of children with speech sound disordersNancy A Raitano
Department of Psychology, University of Denver, Denver, CO 80208, USA
J Child Psychol Psychiatry 45:821-35. 2004..Previous studies have documented that two important dimensions of heterogeneity are the presence of a comorbid language impairment (LI) and the persistence of SSD, but these factors have not been examined separately... - Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism networkSally Ozonoff
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
J Autism Dev Disord 34:139-50. 2004.... - The relation between sluggish cognitive tempo and DSM-IV ADHDChristie A Hartman
Institute for Behavioral Genetics and Department of Psychology, University of Colorado at Boulder, Boulder, Colorado 80309 0447, USA
J Abnorm Child Psychol 32:491-503. 2004..These results suggest that SCT is an internally consistent construct that is significantly associated with DSM-IV inattention... - A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United StatesClyde Francks
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
Am J Hum Genet 75:1046-58. 2004..In addition, the QTL effect may be largely limited to the severe range of reading disability... - Linkage of speech sound disorder to reading disability lociShelley D Smith
University of Nebraska Medical Center, USA
J Child Psychol Psychiatry 46:1057-66. 2005..CONCLUSIONS: It now appears that several RD loci are pleiotropic for SSD, extending the findings of Stein et al. (2004) for the RD locus on Chromosome 3... - TDT-association analysis of EKN1 and dyslexia in a Colorado twin cohortHaiying Meng
Department of Pediatrics, Yale Child Health Research Center, Yale University School of Medicine, 464 Congress Avenue, New Haven, CT 06520-8081, USA
Hum Genet 118:87-90. 2005..Alternatively, the published findings of association with markers in EKN1 may reflect linkage disequilibrium with variation in another gene(s) in the region... - Testing hypotheses regarding the causes of comorbidity: examining the underlying deficits of comorbid disordersSoo Hyun Rhee
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
J Abnorm Psychol 114:346-62. 2005..The ability to distinguish the correct model decreased as the sample size and the correlation between the underlying deficits and the symptom scores decreased, suggesting that the issue of power should be considered carefully... - Analyzing comorbidityBruce F Pennington
Department of Psychology, University of Denver, Denver, CO 80208, USA
Adv Child Dev Behav 33:263-304. 2005 - Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD?Alysa E Doyle
Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Child Psychol Psychiatry 46:774-803. 2005..Thus far, potential endophenotypes for ADHD have not been systematically studied... - Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic reviewErik G Willcutt
Department of Psychology, University of Colorado, Boulder, Colorado 80309, USA
Biol Psychiatry 57:1336-46. 2005..Difficulties with EF appear to be one important component of the complex neuropsychology of ADHD... - Neuropsychological analyses of comorbidity between reading disability and attention deficit hyperactivity disorder: in search of the common deficitErik G Willcutt
Department of Psychology, University of Colorado at Boulder, CO 80309, USA
Dev Neuropsychol 27:35-78. 2005..Slow and variable processing speed was characteristic of all 3 clinical groups, suggesting that measures of this domain may be useful for future studies that search for the common genes that increase susceptibility to RD and ADHD... - Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexiaSimon E Fisher
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK
Nat Genet 30:86-91. 2002..This is the first report of QTL-based genome-wide scanning for a human cognitive trait... - Which children benefit from letter names in learning letter sounds?Rebecca Treiman
Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
Cognition 106:1322-38. 2008..Our results suggest that a wide range of children use the names of letters to help learn the sounds and that phonological awareness, as conventionally measured, is not required in order to do so... - Refinement of the 6p21.3 quantitative trait locus influencing dyslexia: linkage and association analysesKaren E Deffenbacher
Center for Human Molecular Genetics, Munroe Meyer Institute, University of Nebraska Medical Center, NE Medical Center MMI Rm 3085, Omaha, NE 68198 5455, USA
Hum Genet 115:128-38. 2004..The results of the association study have thereby allowed us to significantly reduce the number of possible candidate genes and to prioritize genes for further mutation screening...
Research Grants
- THE LINGUISTIC PHENOTYPE IN FAMILIAL DYSLEXIABruce Pennington; Fiscal Year: 2007....
- LINGUISTIC PHENOTYPE IN FAMILIAL DYSLEXIABruce Pennington; Fiscal Year: 2002....
- THE LINGUISTIC PHENOTYPE IN FAMILIAL DYSLEXIABruce Pennington; Fiscal Year: 2009....