Research Topics
| Philip O'ReillySummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Long-term continuous oxygen treatment in chronic obstructive pulmonary disease: proper use, benefits and unresolved issuesPhilip O'Reilly
Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, USA
Curr Opin Pulm Med 13:120-4. 2007..It is important that long-term oxygen treatment be administered only to those patients who will benefit and in a manner that maximizes its efficacy. New studies are urgently needed to address these questions...
Interfering with extracellular matrix degradation to blunt inflammationPhilip J O'Reilly
Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, THT 442, 1530 3rd Avenue South, Birmingham, AL 35294 0006, United States
Curr Opin Pharmacol 8:242-8. 2008..Elucidation of these pathways may provide novel biomarkers and therapeutic targets for chronic lung diseases...
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPDPhilip O'Reilly
Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, THT 422, 1900 University Blvd, Birmingham, Alabama 35294 0006, USA
Respir Res 10:38. 2009..In this study, we investigate if N-alpha-PGP and PGP are biomarkers and potential therapeutic targets for COPD...
Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagenPhilip J O'Reilly
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 5294 0005, USA
J Neuroimmunol 217:51-4. 2009..This novel, pro-inflammatory role for PE raises the possibility of a self-sustaining pathway of neutrophilic inflammation and may provide biomarkers and therapeutic targets for diseases caused by chronic, neutrophilic inflammation...
Clinical use of exhaled biomarkers in COPDWilliam Bailey
Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, AL 35294 0006, USA
Int J Chron Obstruct Pulmon Dis 2:403-8. 2007..Identification of novel inflammatory mediators in EBC may cast new light on the pathogenesis of COPD and identify new therapeutic targets, which are badly needed in this disease...
Recommendations of the 6th long-term oxygen therapy consensus conferenceDennis E Doherty
Division of Pulmonary Critical Care, Sleep Medicine, University of Kentucky, Lexington, 40536-0284, USA
Respir Care 51:519-25. 2006
National COPD conference summaryA Sonia Buist
Oregon Health and Science University, Portland, Oregon, USA
COPD 1:293-302. 2004..This summary provides the recommendations from the conference that will be used to develop an action plan for the US COPD Coalition. It includes actions proposed by plenary speakers, roundtable faculty and conference participants...
A 4-year trial of tiotropium in chronic obstructive pulmonary diseaseDonald P Tashkin
David Geffen School of Medicine at the University of California, Los Angeles 90095 1690, USA
N Engl J Med 359:1543-54. 2008..Previous studies showing that tiotropium improves multiple end points in patients with chronic obstructive pulmonary disease (COPD) led us to examine the long-term effects of tiotropium therapy...
