Research Topics
| S OgohSummaryAffiliation: University of North Texas Country: USA Publications
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Publications
Increases in central blood volume modulate carotid baroreflex resetting during dynamic exercise in humansShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol 581:405-18. 2007..These findings suggest that changes in cardiopulmonary baroreceptor load influence carotid baroreflex resetting during dynamic exercise...
Effects of changes in central blood volume on carotid-vasomotor baroreflex sensitivity at rest and during exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, Texas 76107, USA
J Appl Physiol 101:68-75. 2006....
Autonomic neural control of the cerebral vasculature: acute hypotensionShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
Stroke 39:1979-87. 2008..This study was designed to compare middle cerebral artery mean blood velocity responses to acute hypotension with and without alpha(1)-adrenoreceptor blockade (Prazosin) in young, healthy humans...
Arterial baroreflex control of muscle sympathetic nerve activity in the transition from rest to steady-state dynamic exercise in humansShigehiko Ogoh
Dept of Integrative Physiology, Univ of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
Am J Physiol Heart Circ Physiol 293:H2202-9. 2007....
Dynamic blood pressure control and middle cerebral artery mean blood velocity variability at rest and during exercise in humansS Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
Acta Physiol (Oxf) 191:3-14. 2007..This study evaluated the influence of cardiac output variability on beat-to-beat middle cerebral artery mean blood velocity (MCA V(mean)) during exercise with and without cardiac beta(1)-adrenergic blockade...
Dynamic cerebral autoregulation during exhaustive exercise in humansShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
Am J Physiol Heart Circ Physiol 288:H1461-7. 2005..05), whereas the phase shift tended to decrease. These findings suggest that dynamic cerebral autoregulation was impaired by exhaustive exercise despite a hyperventilation-induced reduction in Pa(CO(2))...
Middle cerebral artery flow velocity and pulse pressure during dynamic exercise in humansShigehiko Ogoh
Dept of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
Am J Physiol Heart Circ Physiol 288:H1526-31. 2005..However, dynamic CA remains able to modulate blood flow around the exercise-induced increase in MCA V(m), even during high-intensity exercise...
Autonomic nervous system influence on arterial baroreflex control of heart rate during exercise in humansShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center at Fort Worth, TX 76107, USA
J Physiol 566:599-611. 2005..These findings suggest that during exercise the reduction of arterial baroreceptor reflex sensitivity at the operating point was a result of vagal withdrawal rather than an increase in sympathetic activity...
Cardiopulmonary baroreflex is reset during dynamic exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, Texas 76107, USA
J Appl Physiol 100:51-9. 2006..These data indicate that the cardiopulmonary baroreflex had been reset during exercise to the new operating point associated with the exercise-induced change in cardiac filling volume...
The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol 569:697-704. 2005..It appears that the exercise induced sympathoexcitation and the change in the distribution of between the cerebral and the systemic circulation modifies the relationship between MCA V(mean) and ...
Autonomic control of cerebral circulation: exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
Med Sci Sports Exerc 40:2046-54. 2008..These findings suggest that the regulation of CBF during exercise is modulated not only by CA but also by autonomic nervous system and the arterial baroreflex-mediated control of the systemic circulation...
Interaction between the ventilatory and cerebrovascular responses to hypo- and hypercapnia at rest and during exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol 586:4327-38. 2008..8 +/- 0.2% mmHg(-1), P = 0.03). These findings indicate that, despite an attenuated chemoreflex system controlling ventilation, elevations in cerebrovascular reactivity might help maintain CO(2) homeostasis in the brain during exercise...
Onset responses of ventilation and cerebral blood flow to hypercapnia in humans: rest and exerciseShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
J Appl Physiol 106:880-6. 2009....
Haemodynamic changes during neck pressure and suction in seated and supine positionsS Ogoh
Department of Integrative Physiology and Cardiovascular Research Institute, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
J Physiol 540:707-16. 2002..These data indicate that alterations in vasomotor activity are the primary means by which the carotid baroreflex regulates blood pressure during acute changes in carotid sinus transmural pressure...
Role of central command in carotid baroreflex resetting in humans during static exerciseS Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
J Physiol 543:349-64. 2002..Thus the physiological response to exercise requires CC activation to reset the carotid-cardiac reflex but requires either CC or EPR to reset the carotid-vasomotor reflex...
Carotid-cardiac baroreflex function does not influence blood pressure regulation during head-up tilt in humansShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol Sci 56:227-33. 2006..Furthermore, the maintenance of arterial blood pressure during postural stress is primarily mediated by arterial and cardiopulmonary reflex regulation of sympathetic activity and its effects on the systemic vasculature...
Regulation of middle cerebral artery blood velocity during recovery from dynamic exercise in humansShigehiko Ogoh
Dept of Integrative Physiology, Univ of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
J Appl Physiol 102:713-21. 2007....
Baroreflex-mediated changes in cardiac output and vascular conductance in response to alterations in carotid sinus pressure during exercise in humansShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center at Fort Worth, TX, USA and Copenhagen Muscle Research Centre, Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
J Physiol 550:317-24. 2003..017) during heavy exercise. Collectively, these findings indicate that alterations in vasomotion are the primary means by which the CBR regulates blood pressure during mild to heavy exercise...
Carotid baroreflex responsiveness to head-up tilt-induced central hypovolaemia: effect of aerobic fitnessShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center at Fort Worth, TX 76107, USA
J Physiol 551:601-8. 2003..These findings provide an explanation for the predisposition to orthostatic hypotension and intolerance in well-trained athletes...
Does pulsatile and sustained neck pressure or neck suction produce differential cardiovascular and sympathetic responses in humans?Shigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
Exp Physiol 88:595-601. 2003..Furthermore, despite MSNA and HR returning towards baseline during NS, CBR-mediated changes in MAP are well maintained over 20 s of NS and NP...
Arterial baroreflex control of sympathetic nerve activity during acute hypotension: effect of fitnessP J Fadel
Department of Integrative Physiology and Cardiovascular Research Institute, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
Am J Physiol Heart Circ Physiol 280:H2524-32. 2001..These data indicate that the CBR contributes importantly to the MSNA response during acute systemic hypotension. Additionally, we suggest that an impaired control of vascular reactivity hinders blood pressure regulation in HF subjects...
Carotid baroreflex function during and following voluntary apnea in humansN Muenter Swift
Department of Intergrative Physiology, University of North Texas Health Sciences Center, Fort Worth, 76107, USA
Am J Physiol Heart Circ Physiol 285:H2411-9. 2003..e., a downward and leftward shift) upon apnea termination may importantly contribute to the reduced sympathoexcitatory response to NP...
Carotid baroreflex function ceases during vasovagal syncopeShigehiko Ogoh
Department of Integrative Physiology, University of North Texas, Health Science Centre, Fort Worth, Texas, USA
Clin Auton Res 14:30-3. 2004..In addition, during the vasovagal syncope, baroreflex control was suppressed as blood pressure remained low during neck pressure stimuli. In conclusion, arterial baroreflex function ceases during vasovagal syncope...
Standing up to the challenge of standing: a siphon does not support cerebral blood flow in humansE A Dawson
Dept of Anesthesia, Rigshospitalet, Section 2041, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 287:R911-4. 2004....
Carotid baroreflex regulation of sympathetic nerve activity during dynamic exercise in humansP J Fadel
Department of Integrative Physiology and Cardiovascular Research Institute, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
Am J Physiol Heart Circ Physiol 280:H1383-90. 2001..74) across the range of neck chamber pressures. Thus CBR control of sympathetic nerve activity appears to be preserved during moderate-intensity dynamic exercise...
Carotid baroreflex control of leg vasculature in exercising and non-exercising skeletal muscle in humansDavid Melvin Keller
University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol 561:283-93. 2004..05). Collectively, these data indicate that, despite a clear attenuation of the vascular response to MSNA in the exercising leg, CBR-mediated changes in mean arterial pressure were no different between rest and exercise...
Transfer function characteristics of the neural and peripheral arterial baroreflex arcs at rest and during postexercise muscle ischemia in humansShigehiko Ogoh
Dept of Integrative Physiology, Univ of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
Am J Physiol Heart Circ Physiol 296:H1416-24. 2009..These findings suggest that during high-intensity muscle metaboreflex activation an increased ABR gain of the neural arc appears to offset an attenuation of the peripheral arc gain to help maintain the overall ABR control of systemic BP...
Recent insights into carotid baroreflex function in humans using the variable pressure neck chamberPaul J Fadel
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX, USA
Exp Physiol 88:671-80. 2003....
Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscleDavid Melvin Keller
University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
J Physiol 561:273-82. 2004..These findings indicate that K(ATP) channel activity modulates sympathetic vasoconstriction in humans and may prove to be an important mechanism by which functional sympatholysis operates in humans during exercise...
Arterial baroreflex resetting during exercise: a current perspectivePeter B Raven
The Department of Integrative Physiology, University of North Texas, Health Science Center, TX 76107, USA
Exp Physiol 91:37-49. 2006....
Dynamic carotid baroreflex control of the peripheral circulation during exercise in humansD Walter Wray
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
J Physiol 559:675-84. 2004..However, despite a shift towards more predominant local control over the exercising muscle vasculature, systemic arterial blood pressure was well preserved...
Comments on Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow. Autonomic nervous system influences dynamic cerebral blood flowShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, TX, USA
J Appl Physiol 105:1370. 2008
Carotid baroreflex control of leg vascular conductance at rest and during exerciseDavid M Keller
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth 76107, USA
J Appl Physiol 94:542-8. 2003..Furthermore, despite alterations in CBR-induced changes in LVC during exercise, CBR control of blood pressure was well maintained...
Regulatory mechanisms of cerebral blood flow during exercise: new conceptsShigehiko Ogoh
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX, USA
Exerc Sport Sci Rev 37:123-9. 2009..This review focuses on the integrative mechanisms underlying the regulation of cerebral blood flow during exercise...
[Adaptation in properties of skeletal muscle to coronary artery occlusion/reperfusion in rats]Shigehiko Ogoh
Department of Integrative Physiology, Health Science Center at Fort Worth, University of North Texas, Texas 760107-2699, USA
Nippon Seirigaku Zasshi 64:225-36. 2002..However, our data would support the notion that there is a linkage between the function of heart and physiological properties of skeletal muscle...
Cerebral carbohydrate cost of physical exertion in humansMads K Dalsgaard
Department of Anesthesia, Rigshospitalet 2041, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 287:R534-40. 2004..08). A time-dependent cerebral surplus uptake of carbohydrate was not substantiated and, consequently, exhaustive exercise involves a brain surplus carbohydrate uptake of a magnitude comparable with its glycogen content...
Regulation of middle cerebral artery blood velocity during dynamic exercise in humans: influence of agingJames P Fisher
Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO 65212, USA
J Appl Physiol 105:266-73. 2008..older 0.72 +/- 0.07 cm x s(-1) x mmHg(-1) at 50% HRR; P > 0.05). We conclude that despite greater increases in MAP, the regulation of MCAV(mean) is well maintained during dynamic exercise in healthy older middle-aged subjects...
Differential effects of acute hypoxia and high altitude on cerebral blood flow velocity and dynamic cerebral autoregulation: alterations with hyperoxiaPhilip N Ainslie
Dept of Physiology, Univ of Otago, Dunedin, New Zealand
J Appl Physiol 104:490-8. 2008..05). Findings indicate that hyperoxia at HA can partially improve CA and lower BP, with little effect on MCAv...
Cardiac and vasomotor components of the carotid baroreflex control of arterial blood pressure during isometric exercise in humansJames P Fisher
School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
J Physiol 572:869-80. 2006..These data suggest that alterations in vasomotor tone are the primary mechanism by which the CBR modulates blood pressure during low intensity isometric exercise...
Influence of age on cardiac baroreflex function during dynamic exercise in humansJames P Fisher
Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO 65212, USA
Am J Physiol Heart Circ Physiol 293:H777-83. 2007....
Alterations in autonomic function and cerebral hemodynamics to orthostatic challenge following a mountain marathonCarissa Murrell
Department of Physiology, University of Otago, Dunedin, New Zealand
J Appl Physiol 103:88-96. 2007..Such changes may be critical factors in collapse following prolonged exercise...
Effects of hyperglycemia on the cerebrovascular response to rhythmic handgrip exerciseYu Sok Kim
Medium Care Unit, Department of Internal Medicine, F7 205 Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
Am J Physiol Heart Circ Physiol 293:H467-73. 2007..These findings suggest that elevated blood glucose does not explain that dynamic CA is affected during intense exercise...
Alterations in cerebral autoregulation and cerebral blood flow velocity during acute hypoxia: rest and exercisePhilip N Ainslie
Department of Physiology, University of Otago, Dunedin, New Zealand
Am J Physiol Heart Circ Physiol 292:H976-83. 2007..Despite maintaining MCAV, such hypoxic exercise can potentially compromise cerebral autoregulation and oxygenation...
Exercise intensity influences cardiac baroreflex function at the onset of isometric exercise in humansJames P Fisher
Department of Medical Pharmacology and Physiology, MA415 Medical Sciences Bldg, University of Missouri, Columbia, MO 65212, USA
J Appl Physiol 103:941-7. 2007..Collectively, these results suggest that carotid-cardiac baroreflex control is dynamically modulated throughout isometric exercise in humans, whereas carotid baroreflex regulation of blood pressure is well-maintained...
