Cristhiaan D Ochoa

Summary

Affiliation: University of South Alabama
Country: USA

Publications

  1. ncbi Cyclic stretch affects pulmonary endothelial cell control of pulmonary smooth muscle cell growth
    Cristhiaan D Ochoa
    Pulmonary and Critical Care Unit, Massachusetts General Hospital, Bullfinch 148, 55 Fruit Street, Boston, MA 02114, USA
    Am J Respir Cell Mol Biol 39:105-12. 2008
  2. ncbi Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
    Cristhiaan D Ochoa
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    J Cardiothorac Surg 5:32. 2010
  3. ncbi Thrombospondin-1, endothelium and systemic vascular tone
    Cristhiaan D Ochoa
    Department of Pharmacology, University of South Alabama, Mobile, AL, USA
    Future Cardiol 7:169-72. 2011
  4. ncbi Low molecular weight hyaluronan, via AP-1 and NF-?B signalling, induces IL-8 in transformed bronchial epithelial cells
    Christiaan D Ochoa
    Pulmonary and Critical Care Unit, Dept of Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, USA
    Swiss Med Wkly 141:w13255. 2011
  5. ncbi Low-molecular-weight heparin inhibits hypoxic pulmonary hypertension and vascular remodeling in guinea pigs
    Essam Al Ansari
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Chest 132:1898-905. 2007
  6. ncbi The role of hyaluronan synthase 3 in ventilator-induced lung injury
    Kuan Jen Bai
    Pulmonary and Critical Care Unit, Massachusetts General Hospital, 55 Fruit Street, Bulfinch 148, Boston, MA 02114, USA
    Am J Respir Crit Care Med 172:92-8. 2005
  7. ncbi New developments in lung endothelial heterogeneity: Von Willebrand factor, P-selectin, and the Weibel-Palade body
    Cristhiaan D Ochoa
    Department of Pharmacology, University of South Alabama, Mobile, AL 36688, USA
    Semin Thromb Hemost 36:301-8. 2010
  8. ncbi Cold exposure reveals two populations of microtubules in pulmonary endothelia
    Cristhiaan D Ochoa
    Departments of Pharmacology, University of South Alabama, Mobile, Alabama 36688, USA
    Am J Physiol Lung Cell Mol Physiol 300:L132-8. 2011

Collaborators

Detail Information

Publications8

  1. ncbi Cyclic stretch affects pulmonary endothelial cell control of pulmonary smooth muscle cell growth
    Cristhiaan D Ochoa
    Pulmonary and Critical Care Unit, Massachusetts General Hospital, Bullfinch 148, 55 Fruit Street, Boston, MA 02114, USA
    Am J Respir Cell Mol Biol 39:105-12. 2008
    ..The complete identification and understanding of the secreted proteome of stretched PAECs may lead to new insights into the pathophysiology of pulmonary vascular remodeling...
  2. ncbi Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
    Cristhiaan D Ochoa
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    J Cardiothorac Surg 5:32. 2010
    ..In addition, TSP-1 produced by the pulmonary endothelium inhibits pulmonary artery smooth muscle cell growth. Based on these observations we sought to describe the pulmonary vascular changes in TSP-1(-/-) mice exposed to chronic hypoxia...
  3. ncbi Thrombospondin-1, endothelium and systemic vascular tone
    Cristhiaan D Ochoa
    Department of Pharmacology, University of South Alabama, Mobile, AL, USA
    Future Cardiol 7:169-72. 2011
    ..The importance of these two pathways in supporting systemic and pulmonary vascular tone in health and disease is unclear...
  4. ncbi Low molecular weight hyaluronan, via AP-1 and NF-?B signalling, induces IL-8 in transformed bronchial epithelial cells
    Christiaan D Ochoa
    Pulmonary and Critical Care Unit, Dept of Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, USA
    Swiss Med Wkly 141:w13255. 2011
    ..In the present study, it was investigated whether LMW-HA synthesised in the lung, in response to cyclic stretch, increased IL-8 production in the bronchial epithelium...
  5. ncbi Low-molecular-weight heparin inhibits hypoxic pulmonary hypertension and vascular remodeling in guinea pigs
    Essam Al Ansari
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Chest 132:1898-905. 2007
    ..We have shown previously that antiproliferative unfractionated heparins block hypoxia-induced pulmonary arterial hypertension (PAH) and vascular remodeling, and hypothesized that low-molecular-weight heparins (LMWHs) would too...
  6. ncbi The role of hyaluronan synthase 3 in ventilator-induced lung injury
    Kuan Jen Bai
    Pulmonary and Critical Care Unit, Massachusetts General Hospital, 55 Fruit Street, Bulfinch 148, Boston, MA 02114, USA
    Am J Respir Crit Care Med 172:92-8. 2005
    ..We conclude that high VT induced low-molecular-weight hyaluronan production is dependent on de novo synthesis through hyaluronan synthase 3, and plays a role in the inflammatory response of ventilator-induced lung injury...
  7. ncbi New developments in lung endothelial heterogeneity: Von Willebrand factor, P-selectin, and the Weibel-Palade body
    Cristhiaan D Ochoa
    Department of Pharmacology, University of South Alabama, Mobile, AL 36688, USA
    Semin Thromb Hemost 36:301-8. 2010
    ..This information is considered in the context of vasculitis and pneumonia, two pathophysiological processes to which the stimulated secretion of VWF and P-selectin contribute...
  8. ncbi Cold exposure reveals two populations of microtubules in pulmonary endothelia
    Cristhiaan D Ochoa
    Departments of Pharmacology, University of South Alabama, Mobile, Alabama 36688, USA
    Am J Physiol Lung Cell Mol Physiol 300:L132-8. 2011
    ..Hence, pulmonary endothelia have a population of cold-stable microtubules...