Tanya K Murphy

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
    Tanya K Murphy
    Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
    Biol Psychiatry 61:279-84. 2007
  2. ncbi Immunology of obsessive-compulsive disorder
    Tanya K Murphy
    Department of Psychiatry, University of Florida School of Medicine, Gainesville, FL 32610, USA
    Psychiatr Clin North Am 29:445-69. 2006
  3. ncbi Insight in pediatric obsessive-compulsive disorder: associations with clinical presentation
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Psychiatry Res 160:212-20. 2008
  4. ncbi Clinical features associated with treatment-resistant pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 49:35-42. 2008
  5. ncbi Florida Obsessive-Compulsive Inventory: development, reliability, and validity
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Psychol 63:851-9. 2007
  6. ncbi Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 48:313-8. 2007
  7. ncbi Sleep-related problems in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:877-85. 2008
  8. ncbi Peer victimization in children with obsessive-compulsive disorder: relations with symptoms of psychopathology
    Eric A Storch
    Department of Psychiatry and Department of Pediatrics, University of Florida, Box 100234, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 35:446-55. 2006
  9. ncbi Family accommodation in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:207-16. 2007
  10. ncbi Quality of life in youth with Tourette's syndrome and chronic tic disorder
    Eric A Storch
    Department of Psychiatry and Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:217-27. 2007

Research Grants

  1. NEUROIMMUNOLOGY OF CHILDHOOD PSYCHIATRIC DISORDERS
    Tanya Murphy; Fiscal Year: 2005
  2. Prospective Study of 'PANDAS'
    Tanya Murphy; Fiscal Year: 2006

Detail Information

Publications50

  1. ncbi Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
    Tanya K Murphy
    Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
    Biol Psychiatry 61:279-84. 2007
    ..Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) research is based on the hypothesis that infections trigger changes in behavior and movement in children...
  2. ncbi Immunology of obsessive-compulsive disorder
    Tanya K Murphy
    Department of Psychiatry, University of Florida School of Medicine, Gainesville, FL 32610, USA
    Psychiatr Clin North Am 29:445-69. 2006
    ..The assimilation of these study results should allow for elucidation of the immune system's role in the onset and maintenance of OCD...
  3. ncbi Insight in pediatric obsessive-compulsive disorder: associations with clinical presentation
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Psychiatry Res 160:212-20. 2008
    ..These findings suggest that OCD with poor insight may represent a distinct clinical feature that may require more intensive and multimodal treatment approaches...
  4. ncbi Clinical features associated with treatment-resistant pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 49:35-42. 2008
    ..The objective of the study was to identify clinical and sociodemographic characteristics that may differentiate youth with obsessive-compulsive disorder (OCD) who are resistant to treatment vs those who have a favorable response...
  5. ncbi Florida Obsessive-Compulsive Inventory: development, reliability, and validity
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Psychol 63:851-9. 2007
    ..A strength of the FOCI is that it offers a quick evaluation of both presence and severity of OCD symptoms. An important limitation is that the FOCI does not assess the severity of individual symptoms...
  6. ncbi Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Compr Psychiatry 48:313-8. 2007
    ..This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms...
  7. ncbi Sleep-related problems in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:877-85. 2008
    ..These results suggest that SRPs are relatively common in youth with OCD, are associated with symptom severity, and warrant attention during assessment and treatment...
  8. ncbi Peer victimization in children with obsessive-compulsive disorder: relations with symptoms of psychopathology
    Eric A Storch
    Department of Psychiatry and Department of Pediatrics, University of Florida, Box 100234, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 35:446-55. 2006
    ..Recognition of the magnitude of the problem and contribution problematic peer relations may play in comorbid psychological conditions is important for clinicians who see children with OCD...
  9. ncbi Family accommodation in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:207-16. 2007
    ..Family accommodation mediated the relation between symptom severity and parent-rated functional impairment...
  10. ncbi Quality of life in youth with Tourette's syndrome and chronic tic disorder
    Eric A Storch
    Department of Psychiatry and Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Clin Child Adolesc Psychol 36:217-27. 2007
    ....
  11. ncbi The children's Yale-Brown obsessive-compulsive scale: psychometric properties of child- and parent-report formats
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 20:1055-70. 2006
    ..Exploratory factor analyses identified a two-factor structure in both measures comprised of disturbance and severity factors. This study provides preliminary support for the use of child- and parent-report versions of the CY-BOCS...
  12. ncbi Reliability and validity of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    Psychol Assess 17:486-91. 2005
    ..07-.20), and child ratings of depression (r = .02-.26) and anxiety (r = -.06 -.28). Findings suggest that the YGTSS is a reliable and valid instrument for the assessment of pediatric TS...
  13. ncbi Family-based cognitive-behavioral therapy for pediatric obsessive-compulsive disorder: comparison of intensive and weekly approaches
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 46:469-78. 2007
    ..To examine the relative efficacy of intensive versus weekly cognitive-behavioral therapy (CBT) for children and adolescents with obsessive-compulsive disorder (OCD)...
  14. ncbi Sequential cognitive-behavioral therapy for children with obsessive-compulsive disorder with an inadequate medication response: a case series of five patients
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 326110, USA
    Depress Anxiety 24:375-81. 2007
    ..Although a number of limitations of this preliminary report exist, this study provides preliminary support for the utility of an intensive intervention for youth with OCD who have had an inadequate response and/or adverse side effects...
  15. ncbi Convergent and discriminant validity of the Children's Yale-Brown Obsessive Compulsive Scale-Symptom Checklist
    Jason Gallant
    Department of Educational Psychology, University of Florida, Gainesville, FL 32610, United States
    J Anxiety Disord 22:1369-76. 2008
    ..These results provide initial psychometric support for the CY-BOCS-SC and support its use as a clinical and research instrument for assessing presence of a range of obsessive and compulsive symptoms in youth with OCD...
  16. ncbi Aripiprazole augmentation of incomplete treatment response in an adolescent male with obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 25:172-4. 2008
    ..This case suggests that aripiprazole may have utility as an augmenting agent of CBT in adolescents with OCD and underscores the need for conducting controlled studies to test this hypothesis...
  17. ncbi Impact of comorbidity on cognitive-behavioral therapy response in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 47:583-92. 2008
    ..To examine the impact of psychiatric comorbidity on cognitive-behavioral therapy response in children and adolescents with obsessive-compulsive disorder...
  18. ncbi Obsessive-compulsive disorder in youth with and without a chronic tic disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 25:761-7. 2008
    ..Implications of these findings on clinical presentation and treatment efficacy are highlighted...
  19. ncbi Cognitive-behavioral therapy for PANDAS-related obsessive-compulsive disorder: findings from a preliminary waitlist controlled open trial
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Am Acad Child Adolesc Psychiatry 45:1171-8. 2006
    ....
  20. ncbi Effect of comorbid tics on a clinically meaningful response to 8-week open-label trial of fluoxetine in obsessive compulsive disorder
    David S Husted
    Department of Psychiatry, University of Florida College of Medicine, P O Box 100256, Gainesville, FL 32610 0256, USA
    J Psychiatr Res 41:332-7. 2007
    ..Limitations include the relatively low number of tic subjects and the open-label nature of the study. Additional data are needed on how comorbid tics may affect SRI treatment response in OCD...
  21. ncbi D-cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorder
    Eric A Storch
    Departments of Psychiatry, University of Florida, Florida 32610, USA
    Int Clin Psychopharmacol 22:230-7. 2007
    ..As this study is the first to explore this question and a number of methodological issues must be considered when interpreting the findings, the conclusions that may be drawn from our results are limited...
  22. ncbi Factor analytic study of the Children's Yale-Brown Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesvile, FL 32610, USA
    J Clin Child Adolesc Psychol 34:312-9. 2005
    ..These findings suggest that the CY-BOCS Total Score may represent an inaccurate assessment of symptom severity and supports the use of the revised Severity and Disturbance factors in assessing illness severity...
  23. ncbi Further psychometric properties of the Tourette's Disorder Scale-Parent Rated version (TODS-PR)
    Eric A Storch
    Department of Psychiatry, University of Florida, Box 100234, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 35:107-20. 2004
    ..The TODS-PR Total Score and factors showed good convergent validity with other measures of symptomatology and impairment. These findings suggest that the TODS-PR is a reliable and valid parent-rating scale for assessing TD symptoms...
  24. ncbi Associations between miscellaneous symptoms and symptom dimensions in adults with obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610 USA
    Anxiety Stress Coping 21:199-212. 2008
    ..g., hierarchy development)...
  25. ncbi Cognitive behavioral therapy plus motivational interviewing improves outcome for pediatric obsessive-compulsive disorder: a preliminary study
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, Florida, USA
    Cogn Behav Ther 39:24-7. 2010
    ....
  26. ncbi Associations between miscellaneous symptoms and symptom dimensions: an examination of pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Behav Res Ther 45:2593-603. 2007
    ..g., understanding which miscellaneous symptoms relate to certain dimensions) and treatment implications (e.g., hierarchy development)...
  27. ncbi Obsessive-compulsive disorder in Tourette syndrome
    Wayne K Goodman
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Child Neurol 21:704-14. 2006
    ....
  28. ncbi Cognitive-behavioral therapy for obsessive-compulsive disorder: a non-randomized comparison of intensive and weekly approaches
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 22:1146-58. 2008
    ..Since many people with OCD do not have access to trained CBT providers, intensive treatment may be a viable option in such cases...
  29. ncbi Clinical predictors of early fluoxetine treatment response in obsessive-compulsive disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 23:429-33. 2006
    ..Furthermore, findings suggest early predictors of patients with certain characteristics who may ultimately need adjunctive care to facilitate response...
  30. ncbi Reliability and validity of the Child Behavior Checklist Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    J Anxiety Disord 20:473-85. 2006
    ..Suggestions for cutoff scores are provided using results from ROC analyses. Overall, these findings suggest that the OCS-R is a reliable and valid instrument for the assessment of pediatric OCD...
  31. ncbi A measure of functional impairment in youth with Tourette's syndrome
    Eric A Storch
    Department of Psychiatry, University of Florida, Box 100234, Gainesville, FL 32610, USA
    J Pediatr Psychol 32:950-9. 2007
    ..The current study was undertaken to examine both tic-related impairment and impairment from other psychological problems in 59 youth (mean age 11.4 years, 69% male) with TS...
  32. ncbi Further psychometric examination of the Tourette's Disorder Scales
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 38:89-98. 2007
    ..Excellent inter-rater agreement and convergent and divergent validity was found. These results provide further psychometric support for the TODS-PR and TODS-CR...
  33. ncbi SSRI adverse events: how to monitor and manage
    Tanya K Murphy
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Int Rev Psychiatry 20:203-8. 2008
    ..With diligence to appropriate prescribing and monitoring, the benefits of therapy outweigh the potential of treatment related risk...
  34. ncbi Yale-Brown Obsessive Compulsive Scale: the dimensional structure revisited
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 22:28-35. 2005
    ..Reliability and convergent validity of these factors were generally satisfactory, although divergent validity was not entirely supported. Implications of these findings on scoring the Y-BOCS are discussed...
  35. ncbi Assessment of pediatric obsessive-compulsive disorder: a critical review of current methodology
    Lisa J Merlo
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Child Psychiatry Hum Dev 36:195-214. 2005
    ..Finally, a critical review is offered of major trends in the assessment of pediatric OCD (e.g., diagnostic interviews, self-report and parent-report measures, and clinician-administered inventories)...
  36. ncbi Factor-analytic study of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Psychiatry Res 149:231-7. 2007
    ..These findings support the use of the original scoring structure in assessing pediatric tic severity...
  37. ncbi Current directions in pediatric obsessive-compulsive disorder
    Adam B Lewin
    Department of Clinical and Health Psychology, University of Florida Health Science Center, Gainesville, FL 32610, USA
    Pediatr Ann 34:128-34. 2005
    ..Additionally, intervention studies for children with significant comorbid psychopathology should be pursued...
  38. ncbi Psychometric evaluation of the Children's Yale-Brown Obsessive-Compulsive Scale
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
    Psychiatry Res 129:91-8. 2004
    ..Findings suggest that the CY-BOCS is a reliable and valid instrument for the assessment of childhood obsessions and compulsions...
  39. ncbi Risk of adverse behavioral effects with pediatric use of antidepressants
    Wayne K Goodman
    Department of Psychiatry, University of Florida College of Medicine, McKnight Brain Institute, Room L4 100, P O Box 100256, Gainesville, FL 32610 0256, USA
    Psychopharmacology (Berl) 191:87-96. 2007
    ....
  40. ncbi Evaluation of open-label topiramate for scar therapy
    Nathan A Shapira
    Department of Psychiatry, College of Medicine and the Evelyn F and William McKnight Brain Institute, University of Florida, Gainesville, USA
    Dermatol Online J 9:3. 2003
    ..025). The data indicate that topiramate may be a safe and effective treatment for scar therapy...
  41. ncbi Topiramate attenuates self-injurious behaviour in Prader-Willi Syndrome
    Nathan A Shapira
    Department of Psychiatry, Evelyn F and William L McKnight Brain Institute of the University of Florida, Gainsville 32610 0256, USA
    Int J Neuropsychopharmacol 5:141-5. 2002
    ....
  42. ncbi Peer victimization and the development of obsessive-compulsive disorder in adolescence
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 21:41-4. 2005
    ..This case illustrates how negative peer experiences may be related to the development and maintenance of OCD...
  43. ncbi Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics
    Tanya K Murphy
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610-0256, USA
    Biol Psychiatry 55:61-8. 2004
    ..03). CONCLUSIONS: Patients with marked obsessive-compulsive/tic symptom changes may be characterized by streptococcal titer elevations and exhibit evidence of seasonal tic exacerbations...
  44. ncbi A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder
    Nathan A Shapira
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida 32610-0256, USA
    Biol Psychiatry 55:553-5. 2004
    ..CONCLUSIONS: These findings indicate no additional advantage of adding olanzapine for 6 weeks in OCD patients who have not had a satisfactory response to fluoxetine for 8 weeks, compared with extending the monotherapy trial...
  45. ncbi Preclinical/Clinical evidence of central nervous system infectious etiology in PANDAS
    Tanya K Murphy
    Department of Psychiatry, University of Florida, USA
    Adv Neurol 99:148-58. 2006
  46. ncbi Case series on the use of aripiprazole for Tourette syndrome
    Tanya K Murphy
    Int J Neuropsychopharmacol 8:489-90. 2005
  47. ncbi Avoiding deep brain stimulation failures in Tourette syndrome
    Michael S Okun
    J Neurol Neurosurg Psychiatry 79:111-2. 2008
  48. ncbi Priapism associated with oxcarbazepine, aripiprazole, and lithium
    Brett Negin
    J Am Acad Child Adolesc Psychiatry 44:1223-4. 2005
  49. ncbi Cardiac involvement in children with PANDAS
    Ana R Segarra
    J Am Acad Child Adolesc Psychiatry 47:603-4. 2008
  50. ncbi [Autoimmunity in obsessive-compulsive disorder and tic disorders]
    Tanya K Murphy
    Rev Bras Psiquiatr 26:218-9. 2004

Research Grants2

  1. NEUROIMMUNOLOGY OF CHILDHOOD PSYCHIATRIC DISORDERS
    Tanya Murphy; Fiscal Year: 2005
    ..This award, along with support from the University Florida Brain Institute and the Department of Psychiatry, will enable the candidate to build a strong foundation of research skills needed to become an independent investigator. ..
  2. Prospective Study of 'PANDAS'
    Tanya Murphy; Fiscal Year: 2006
    ..The results will help determine if antimicrobial interventions are warranted in certain subtypes of pediatric OCD or TS. ..