S Murakami

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. ncbi A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado at Boulder 80309 0447, USA
    Genetics 143:1207-18. 1996
  2. ncbi Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene
    S Murakami
    Institute for Behavioral Genetics, University of Colorado at Boulder 80309 0447, USA
    Curr Biol 8:1091-4. 1998
  3. ncbi Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors
    T E Johnson
    Institute for Behavioral Genetics, Box 447, University of Colorado at Boulder, 80309, USA
    Exp Gerontol 35:687-94. 2000
  4. ncbi The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Curr Biol 11:1517-23. 2001
  5. ncbi Paralogy and orthology of tyrosine kinases that can extend the life span of Caenorhabditis elegans
    B A Rikke
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Mol Biol Evol 17:671-83. 2000
  6. ncbi Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
    Ann N Y Acad Sci 908:40-9. 2000
  7. ncbi Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease
    T E Johnson
    Institute for Behavioral Genetics, University of Colorado at Boulder, 80309, USA
    J Inherit Metab Dis 25:197-206. 2002
  8. ncbi Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity
    T Wada
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Japan
    Mol Cell Biol 21:1633-46. 2001
  9. ncbi Effect of aging on blood pressure in Leh, Ladakh, a high-altitude (3524 m) community, by comparison with a Japanese town
    K Otsuka
    Department of Medicine, Medical Center East, Division of Neurocardiology and Chronoecology, Tokyo Women s Medical University, Nishiogu 2 1 10, Arakawa, Tokyo 116 8567, Japan
    Biomed Pharmacother 59:S54-7. 2005
  10. ncbi Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study
    S Murakami
    Department of Medicine, Medical Center East, Tokyo Women's Medical University, Nishiogu 2-1-10, Arakawa, Tokyo 116-8567, Japan
    Biomed Pharmacother 59:S49-53. 2005

Collaborators

  • T E Johnson
  • B A Rikke
  • Shoichiro Yano
  • Kiyosumi Shibata
  • Y Sato
  • Takashi Ueda
  • Toshiyasu Sasaoka
  • K Otsuka
  • T Wada
  • K Matsubayashi
  • F Halberg
  • K Okumiya
  • K Ichihara
  • M Ishine
  • N Hotta
  • O Matsuoka
  • G Cornelissen
  • Y Kubo
  • T Yamanaka
  • Y Nishimura
  • T Tsugoshi
  • T Norboo
  • Y Otsuka
  • G Yamanaka
  • W Wei
  • D Angchuk
  • H Saitoh
  • M Nishinaga
  • M Shinagawa
  • C Narushima
  • S Nunoda
  • H Higuchi
  • M Hayajiri
  • Y Ebihara
  • D Dorjsuren
  • H Mitsuzawa
  • A Takashima
  • Y Lin
  • T Nomura
  • N Hayashi
  • T Chogyal
  • T Choygal
  • T Ozawa
  • M Miyamoto
  • J Tsukada
  • S Okushiba
  • Y Cho
  • T Shichinohe
  • Y Kawarada
  • H Kaneko
  • A Fukunaga
  • H Katoh
  • Y Murakami
  • H Hashimoto
  • T Itoh
  • H Uehara
  • S Kondo
  • G Mitsutake
  • S Ohkawa
  • H Sano
  • S Takenaka
  • N Matsushima
  • T Haruta
  • M Funaki
  • I Wada
  • W Ogawa
  • K Aoki
  • W Qin
  • M Kobayashi
  • H Ishihara
  • H Hori
  • T Himi
  • T Asano
  • Y Kuroki
  • D Iwaki
  • M Ishiki
  • T Yamashita
  • Y Serino
  • M Nakanishi
  • M Misago
  • Y Kominato
  • R Ogawa
  • I Morimoto
  • S Eto
  • P E Auron
  • S Tonai

Detail Information

Publications22

  1. ncbi A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado at Boulder 80309 0447, USA
    Genetics 143:1207-18. 1996
    ..We propose that life span and some aspects of stress resistance are jointly negatively regulated by a set of gerontogenes (genes whose alteration causes life extension) in C. elegans...
  2. ncbi Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene
    S Murakami
    Institute for Behavioral Genetics, University of Colorado at Boulder 80309 0447, USA
    Curr Biol 8:1091-4. 1998
    ..This transgenic system is an effective means for identifying overexpression gerontogenes...
  3. ncbi Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors
    T E Johnson
    Institute for Behavioral Genetics, Box 447, University of Colorado at Boulder, 80309, USA
    Exp Gerontol 35:687-94. 2000
    ..We suggest that the role of the Age genes in both longevity and stress resistance indicates that a major evolutionary determinant of longevity is the ability to respond to stress...
  4. ncbi The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Curr Biol 11:1517-23. 2001
    ..This study reveals a new system for specifying longevity and stress resistance and suggests possible mechanisms for mediating life extension by dietary restriction and hormesis...
  5. ncbi Paralogy and orthology of tyrosine kinases that can extend the life span of Caenorhabditis elegans
    B A Rikke
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Mol Biol Evol 17:671-83. 2000
    ....
  6. ncbi Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans
    S Murakami
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
    Ann N Y Acad Sci 908:40-9. 2000
    ..Interestingly, increased resistance to environmental stress shows a strong correlation with life extension...
  7. ncbi Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease
    T E Johnson
    Institute for Behavioral Genetics, University of Colorado at Boulder, 80309, USA
    J Inherit Metab Dis 25:197-206. 2002
    ..In mammals, both dietary restriction and hormesis are phenomena in which the endogenous level of resistance to stress has been upregulated; both of these interventions extend longevity, suggesting possible evolutionary conservation...
  8. ncbi Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity
    T Wada
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Japan
    Mol Cell Biol 21:1633-46. 2001
    ....
  9. ncbi Effect of aging on blood pressure in Leh, Ladakh, a high-altitude (3524 m) community, by comparison with a Japanese town
    K Otsuka
    Department of Medicine, Medical Center East, Division of Neurocardiology and Chronoecology, Tokyo Women s Medical University, Nishiogu 2 1 10, Arakawa, Tokyo 116 8567, Japan
    Biomed Pharmacother 59:S54-7. 2005
    ..Longitudinal observations of effects of socio-ecologic factors on the cardiovascular system should help prevent strokes and other cardiovascular events, especially at high altitude...
  10. ncbi Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study
    S Murakami
    Department of Medicine, Medical Center East, Tokyo Women's Medical University, Nishiogu 2-1-10, Arakawa, Tokyo 116-8567, Japan
    Biomed Pharmacother 59:S49-53. 2005
    ..351 (1.029-5.372) and 2.890 (1.059-7.891), respectively. Carotid IMT assessed by ultrasonography is positively associated with an increased risk of all-cause and cardiovascular death in elderly community-dwelling people...
  11. ncbi Fractal analysis of heart rate variability and mortality in elderly community-dwelling people -- Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study
    N Hotta
    Department of Medicine, Medical Center East, Tokyo Women's Medical University, Nishiogu 2-1-10, Arakawa, Tokyo 116-8567, Japan
    Biomed Pharmacother 59:S45-8. 2005
    ....
  12. ncbi Arterial stiffness independently predicts cardiovascular events in an elderly community -- Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study
    O Matsuoka
    Department of Medicine, Division of Neurocardiology and Chronoecology, Tokyo Women s Medical University, Medical Center East, Nishiogu 2 1 10, Arakawa, Tokyo 116 8567, Japan
    Biomed Pharmacother 59:S40-4. 2005
    ..The early detection of risk by chronomics allows the timely institution of prophylactic measures, thereby shifting the focus from rehabilitation to prehabilitation medicine, as a public service to several Japanese towns...
  13. ncbi Positive impact of social intervention on disturbed neurobehavioral function in an elderly community-dwelling population: longitudinal investigation for longevity and aging in Hokkaido County (LILAC)
    S Murakami
    Tokyo Women s Medical University, Daini Hospital, Department of Medicine, Division of Neurocardiology and Chronoecology, Nishiogu 2 1 10, Arakawa ku, Tokyo 116 8567, Japan
    Biomed Pharmacother 58:S45-7. 2004
    ..Direct social intervention, including lifestyle modification can have a positive impact, notably on subjects with cardiovascular disorders...
  14. ncbi Over-expression of E2F-1 in esophageal squamous cell carcinoma correlates with tumor progression
    Y Ebihara
    Surgical Oncology, Cancer Medicine, Division of Cancer Medicine, Hokkaido University Graduate School of Medicine, Hokkaido, Japan
    Dis Esophagus 17:150-4. 2004
    ..0290). Over-expression of E2F-1 is associated with tumor progression and a worse prognosis after surgery in ESCC...
  15. ncbi Chronomics for chronoastrobiology with immediate spin-offs for life quality and longevity
    K Otsuka
    Division of Neurocardiology and Chronoecology, Department of Medicine, Tokyo Women's Medical University, Daini Hospital, Nishiogu 2-1-10, Arakawa-ku, Tokyo, 116-8567, Japan
    Biomed Pharmacother 57:1s-18s. 2003
    ..Cognitive function was maintained or improved, especially for people suffering from hypertension, tachycardia, or a decreased HRV, suggesting that cardiovascular function is a major factor affecting cognitive function...
  16. ncbi RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein
    D Dorjsuren
    Department of Molecular Oncology, Cancer Research Institute, Kanazawa University, Kanazawa 920 0934, Japan
    Mol Cell Biol 18:7546-55. 1998
    ..These results suggest that RMP negatively modulates RNA polymerase II function by binding to RPB5 and that HBx counteracts the negative role of RMP on transcription indirectly by interacting with RPB5...
  17. ncbi Regulation by two CatR proteins that differ in binding affinity to catB promoters expressing two cat gene clusters
    A Takashima
    Division of Bioscience, The Graduate School of Science and Technology, Kobe University, Rokko, Japan
    Biosci Biotechnol Biochem 65:2146-53. 2001
    ..However, the amount of MC II synthesized was larger than that of MC I at low concentrations. On the basis of these results, we concluded that the catB2 promoter was activated at low concentrations of cis,cis-muconate...
  18. ncbi Human T-cell leukemia virus type I Tax transactivates the promoter of human prointerleukin-1beta gene through association with two transcription factors, nuclear factor-interleukin-6 and Spi-1
    J Tsukada
    First Department of Internal Medicine, School of Medicine and the School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
    Blood 90:3142-53. 1997
    ....
  19. ncbi Extracellular Toll-like receptor 2 region containing Ser40-Ile64 but not Cys30-Ser39 is critical for the recognition of Staphylococcus aureus peptidoglycan
    H Mitsuzawa
    First Department of Biochemistry, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan
    J Biol Chem 276:41350-6. 2001
    ....
  20. ncbi Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting
    T Ueda
    Department of Anatomy and Neuroscience, Nagoya City University Medical School, Nagoya, Japan
    Biochem Biophys Res Commun 285:147-51. 2001
    ..The identification of nucleotide diversity and amino acid polymorphisms in human T2R receptors could help clarify individual differences in the acceptability and sensitivity to bitter compounds...
  21. ncbi Direct interaction between the subunit RAP30 of transcription factor IIF (TFIIF) and RNA polymerase subunit 5, which contributes to the association between TFIIF and RNA polymerase II
    W Wei
    Department of Molecular Oncology, Cancer Research Institute, Kanazawa University, Takara machi 13 1, Kanazawa 920 0934, Japan
    J Biol Chem 276:12266-73. 2001
    ..The exposed domain of RPB5 interacts with RAP30 of TFIIF and is important for the association between pol II and TFIIF...
  22. ncbi Chronoecological health watch of arterial stiffness and neuro-cardio-pulmonary function in elderly community at high altitude (3524 m), compared with Japanese town
    K Otsuka
    Department of Medicine, Medical Center East, Tokyo Women s Medical University, Nishiogu 2 1 10, Arakawa, Tokyo 116 8567, Japan
    Biomed Pharmacother 59:S58-67. 2005
    ....