ADRIAN MORRISONSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
Perverting medical history in the service of "animal rights"Adrian R Morrison
Laboratory for Study of the Brain in Sleep, Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA
Perspect Biol Med 45:606-19. 2002..This essay reveals the distortions by a number of such medically trained individuals that I and several colleagues have uncovered...- Hypoglycemia activates arousal-related neurons and increases wake time in adult ratsNancy C Tkacs
School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Physiol Behav 91:240-9. 2007..Basal forebrain cholinergic nuclei also showed increased Fos-immunoreactivity after insulin. These correlated behavioral and histological data provide targets for future studies of the neural pathways underlying hypoglycemic arousal... - A rodent model of sleep disturbances in posttraumatic stress disorder: the role of context after fear conditioningAaron C Pawlyk
Laboratory for the Study of the Brain in Sleep, Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA
Biol Psychiatry 57:268-77. 2005..Animals that were mock-trained showed no changes in sleep. CONCLUSIONS: Shock training induced days-long changes in sleep architecture that were disrupted when the animal was exposed to situational reminders of the training context... - The central nucleus of the amygdala and the wake-promoting effects of modafinilAmy J Silvestri
Laboratory for Study of the Brain in Sleep, Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104, USA
Brain Res 941:43-52. 2002..Injection of modafinil into the ACe did not affect sleep architecture. Thus, ACe does not play a simple role in modafinil's wake-promoting action. We suggest that more complex testing will be required to elucidate its role... - Sleep-related neurons in the central nucleus of the amygdala of rats and their modulation by the dorsal raphe nucleusSushil K Jha
Laboratory for Study of the Brain in Sleep, The School of Veterinary Medicine, USA
Physiol Behav 86:415-26. 2005.... - Long-term effect of cued fear conditioning on REM sleep microarchitecture in ratsVibha Madan
Laboratory for Study of the Brain in Sleep, Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104 6045, USA
Sleep 31:497-503. 2008..To study long-term effects of conditioned fear on REM sleep (REMS) parameters in albino rats... - Developing an ethical view on the use of animals in biomedical research. Fourth Walter C. Randall Lecture on Biomedical EthicsAdrian R Morrison
University of Pennsylvania, USA
Physiologist 45:135, 139-44. 2002 - Differential effect of sleep-wake states on lingual and dorsal neck muscle activity in ratsJackie W Lu
Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104-6046, USA
Respir Physiol Neurobiol 147:191-203. 2005..In obstructive sleep apnea subjects, the sleep-wake changes in the activity of pharyngeal muscles may become similar to those in postural muscles as a result of pharyngeal tone adaptations to the disorder... - "Animal rights" terrorists/extremists: A serious threat to medicineAdrian R Morrison
Mo Med 103:467-71. 2006 - Tetrodotoxin inactivation of pontine regions: influence on sleep-wake statesLarry D Sanford
Sleep Research Laboratory, Department of Pathology and Anatomy, Eastern Virginia Medical School, PO Box 1980, Norfolk, VA 23501, USA
Brain Res 1044:42-50. 2005..The results complement studies that have implicated RPO and SubC in REM generation. REM-A was not observed, suggesting that REM-A is a complex phenomenon that requires time for reorganization of the nervous system after insult... - REM sleep: a sensitive index of fear conditioning in ratsSushil K Jha
Medical Research Service (151, Philadelphia VA Medical Center, Philadelphia, USA
Eur J Neurosci 21:1077-80. 2005..Results are discussed in terms of the decreases in REM as a response to conditioned fear, and the relevance of these findings to the sleep changes seen in post-traumatic stress disorder (PTSD)... - Stress-induced changes in sleep in rodents: models and mechanismsAaron C Pawlyk
Women s Health and Musculoskeletal Biology, Wyeth Research, Collegeville, PA 19426, USA
Neurosci Biobehav Rev 32:99-117. 2008..A complete understanding of the neural correlates of stress-induced sleep alterations may lead to novel treatments for a variety of debilitating sleep disorders...
Research Grants
- Amygdalar Modulation of Fear-Conditioned Changes in REM SleepADRIAN MORRISON; Fiscal Year: 2007..It is very important to investigate the serotonergic modulation of CFC in animals because drugs that influence 5-HT function have widespread acceptance for treating PTSD yet little is known about their actions in related animal models. ..
- BRAINSTEM MECHANISMS OF ALERTINGADRIAN MORRISON; Fiscal Year: 2002..These experiments address basic mechanisms likely to be altered in narcolepsy and PTSD. ..
- Amygdalar Modulation of Fear-Conditioned Changes in REM SleepADRIAN MORRISON; Fiscal Year: 2009..It is very important to investigate the serotonergic modulation of CFC in animals because drugs that influence 5-HT function have widespread acceptance for treating PTSD yet little is known about their actions in related animal models. ..