Research Topics
| Paul MooreSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Type 1 diabetes mellitus and oral health: assessment of tooth loss and edentulismP A Moore
University of Pittsburgh, School of Dental Medicine, PA 15261, USA
J Public Health Dent 58:135-42. 1998..The goal of this exploratory cross-sectional evaluation was to described the characteristics related to partial tooth loss edentulism in subjects with Type 1 diabetes mellitus...- Educational experiences and preparedness in dental anesthesia: five-year outcome assessment and conclusionsPaul A Moore
Department of Anesthesiology, University of Pittsburgh School of Dental Medicine, G89 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA
J Dent Educ 73:1379-86. 2009.... - Periodontal ligament and intraosseous anesthetic injection techniques: alternatives to mandibular nerve blocksPaul A Moore
Department of Dental Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Am Dent Assoc 142:13S-8S. 2011..The authors also present indications for and complications associated with these techniques... - The anesthetic efficacy of 4 percent articaine 1:200,000 epinephrine: two controlled clinical trialsPaul A Moore
Department of Anesthesiology, Oral Health Science Institute, School of Dental Medicine, University of Pittsburgh, 552 Salk Hall, Pittsburgh, PA 15261, USA
J Am Dent Assoc 137:1572-81. 2006.... - Hemostatic and anesthetic efficacy of 4% articaine HCl with 1:200,000 epinephrine and 4% articaine HCl with 1:100,000 epinephrine when administered intraorally for periodontal surgeryPaul A Moore
Department of Pharmacology and Dental Public Health, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261
J Periodontol 78:247-53. 2007.... - Burning mouth syndrome and peripheral neuropathy in patients with type 1 diabetes mellitusPaul A Moore
Oral Health Science Institute, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15206, USA
J Diabetes Complications 21:397-402. 2007..Burning mouth syndrome (BMS) has been attributed secondarily to diabetes, poor glycemic control, and diabetic neuropathy. The prevalence and predictor factors of BMS were compared in type 1 diabetes mellitus (T1DM) and nondiabetic subjects... - A case for the lowly case reportPaul A Moore
University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Anesth Prog 54:175-7. 2007 - Pharmacokinetics of lidocaine with epinephrine following local anesthesia reversal with phentolamine mesylatePaul A Moore
Department of Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Anesth Prog 55:40-8. 2008..The phentolamine-induced delay of the lidocaine Tmax likely represents phentolamine's ability to accelerate the systemic absorption of lidocaine from oral tissues into the systemic circulation... - Diabetes: a growing epidemic of all agesPaul A Moore
Department of Dental Public Health, Oral Health Science Institute, University of Pittsburgh, School of Dental Medicine, PA 15261, USA
J Am Dent Assoc 134:11S-15S. 2003..Despite greater knowledge of the disease, one-third of people with the disease are undiagnosed. Recent estimates indicate that one in three U.S. children born in 2000 will develop diabetes... - Common medications prescribed for adolescent dental patientsPaul A Moore
School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, 552 Salk Hall, Pittsburgh, PA 15261, USA
Dent Clin North Am 50:139-49, vii. 2006..This overview identifies prescription medications commonly used by adolescent patients and discusses their possible impact on dental care... - Local anesthetics: pharmacology and toxicityPaul A Moore
Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
Dent Clin North Am 54:587-99. 2010..This introductory article provides a brief update of the clinical pharmacology of local anesthetic agents and formulations used in dentistry at present... - Type 1 diabetes mellitus and oral health: assessment of periodontal diseaseP A Moore
University of Pittsburgh, School of Dental Medicine, Department of Dental Public Health, PA 15261, USA
J Periodontol 70:409-17. 1999..These patients had been monitored at 2-year intervals as part of a large University of Pittsburgh longitudinal study assessing the medical complications associated with insulin dependent diabetes... - Celecoxib and rofecoxib. The role of COX-2 inhibitors in dental practiceP A Moore
Department of Public Health Dentistry, University of Pittsburgh School of Dental Medicine, 380 Salk Hall, Pittsburgh, PA 15261, USA
J Am Dent Assoc 132:451-6. 2001..Two NSAIDs that recently came on the market, celecoxib and rofecoxib, have been developed to limit the adverse effects seen after chronic use of NSAIDs... - Paresthesias in dentistryPaul A Moore
Department of Dental Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Dent Clin North Am 54:715-30. 2010.... - Type 1 diabetes mellitus, xerostomia, and salivary flow ratesP A Moore
School of Dental Medicine, Department of Dental Public Health, University of Pittsburgh, PA 15261, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:281-91. 2001..This report describes the prevalence of dry-mouth symptoms (xerostomia), the prevalence of hyposalivation in this population, and the possible interrelationships between salivary dysfunction and diabetic complications... - Type 1 diabetes mellitus and oral health: assessment of coronal and root cariesP A Moore
Department of Dental Public Health, University of Pittsburgh, School of Dental Medicine, PA 15261, USA
Community Dent Oral Epidemiol 29:183-94. 2001.... - The efficacy of six local anesthetic formulations used for posterior mandibular buccal infiltration anesthesiaMohammad Abdulwahab
Department of Dental Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Am Dent Assoc 140:1018-24. 2009.... - Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adultsElliot V Hersh
Oral and Maxillofacial Surgery and Pharmacology, School of Dental Medicine, University of Pennsylvania, 240 S 40th Street, Philadelphia, PA 19104, USA
J Am Dent Assoc 139:1080-93. 2008..The study involved 484 subjects who received one of four commercially available local anesthetic solutions containing vasoconstrictors for restorative or scaling procedures... - Complications associated with anesthesia administered for dental treatmentSean G Boynes
Department of Anesthesiology, UPSDM, Pittsburgh, Pennsylvania, USA
Gen Dent 58:e20-5. 2010..The overall complication rate from anesthesia administered during dental care is similar to or less than that reported within the hospital operating system environment... - Dental therapeutic practice patterns in the U.S. I. Anesthesia and sedationPaul A Moore
Oral Health Science Institute, University of Pittsburgh School of Dental Medicine, USA
Gen Dent 54:92-8. 2006..The most frequently selected local anesthetic formulations were 2% lidocaine, 1:100,000 epinephrine for surgical anesthesia and 0.5% bupivacaine, 1:200,000 epinephrine for postoperative pain management... - Adverse drug reactions to local anesthesiaRichard L Finder
Department of Physiology and Pharmacology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
Dent Clin North Am 46:747-57, x. 2002..Serious reactions are extremely infrequent and, when treated properly, unlikely to result in significant morbidity or mortality... - The pharmacokinetics and cardiovascular effects of high-dose articaine with 1:100,000 and 1:200,000 epinephrineElliot V Hersh
Oral and Maxillofacial Surgery and Pharmacology, School of Dental Medicine, University of Pennsylvania, 240 South 40th St, Philadelphia, PA 19104 6003, USA
J Am Dent Assoc 137:1562-71. 2006..9 milliliters of 4 percent articaine hydrochloride (HCl) plus 1:100,000 epinephrine (A100) with those of 11.9 mL of 4 percent articaine HCl plus 1:200,000 epinephrine (A200)... - Practice characteristics among dental anesthesia providers in the United StatesSean G Boynes
Department of Anesthesiology, School of Dental Medicine, Pittsburgh, Pennsylvania 15261, USA
Anesth Prog 57:52-8. 2010..These distinctions include representation of sedation/anesthesia providers across all disciplines of the dental profession, as well as variations in the techniques used for sedation/anesthesia care... - The therapeutic applications of and risks associated with acetaminophen use: a review and updateJames Guggenheimer
Department of Diagnostic Services, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA
J Am Dent Assoc 142:38-44. 2011..S. Food and Drug Administration's (FDA's) revision of warning labeling for over-the-counter (OTC) acetaminophen, or N-acetyl-p-aminophenol (APAP), products, the authors reviewed APAP's potential for liver toxicity... - Xerostomia: etiology, recognition and treatmentJames Guggenheimer
Department of Oral Medicine and Pathology, School of Dental Medicine, University of Pittsburgh, PA 15261, USA
J Am Dent Assoc 134:61-9; quiz 118-9. 2003..When xerostomia is the result of a reduction in salivary flow, significant oral complications can occur... - Complications associated with anesthesia administration for dental treatment in a special needs clinicSean G Boynes
Department of Anesthesiology, University of Pittsburgh, School of Dental Medicine, Pittsburgh, Pennsylvania, USA
Spec Care Dentist 30:3-7. 2010..Our findings show that anesthesia administered during dental treatment for patients with special needs is safe and effective... - Medication-induced hyposalivation: etiology, diagnosis, and treatmentPaul A Moore
Department of Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pennsylvania, USA
Compend Contin Educ Dent 29:50-5. 2008..The general approach to patients with hyposalivation and xerostomia is directed at palliative treatment for the relief of symptoms and prevention of oral complications... - The diabetes-oral health connectionPaul A Moore
Department of Dental Public Health, University of Pittsburgh, School of Dental Medicine, Pittsburgh, Pennsylvania, USA
Compend Contin Educ Dent 23:14-20. 2002 - Dental therapeutics update. IntroductionPaul A Moore
Department of Dental Public Health, University of Pittsburgh, School of Dental Medicine, 552 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA
Dent Clin North Am 46:xv-xviii. 2002 - Dental therapeutic practice patterns in the U.S. II. Analgesics, corticosteroids, and antibioticsPaul A Moore
Oral Health Science Institute, University of Pittsburgh School of Dental Medicine, USA
Gen Dent 54:201-7; quiz 208, 221-2. 2006..The frequency with which oral and maxillofacial surgeons administered antibiotics and corticosteroids varied widely based on perceived patient need and dentist expectations... - The patient with asthma: implications for dental practiceJames Guggenheimer
School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Compend Contin Educ Dent 30:200-2, 205-7; quiz 208, 210. 2009.... - Analgesic update: tapentadol hydrochlorideElliot V Hersh
School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Compend Contin Educ Dent 31:594-9; quiz 600, 603. 2010.... - Local anesthesia: advances in agents and techniquesJ Mel Hawkins
Continuing Education Program, Faculty of Dentistry, University of Toronto, 4800 Leslie Street, Suite 111, Toronto, Ontario, Canada M2J2K9
Dent Clin North Am 46:719-32, ix. 2002..This article provides a brief review of the local anesthetic agents, formulations, and techniques used in dentistry with special emphasis on newly introduced agents and procedures... - Pain control and anxiety management for periodontal therapiesKatherine E Wilson
Department of Sedation, School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK
Periodontol 2000 46:42-55. 2008 - Adverse drug interactions in dentistryElliot V Hersh
Division of Pharmacology, University of Pennsylvania School of Dental Medicine, Philadelphia, USA
Periodontol 2000 46:109-42. 2008 - Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patientsMary Tavares
Clinical Research Collaborative, The Forsyth Institute, 140 The Fenway, Boston, MA 02115, USA
J Am Dent Assoc 139:1095-104. 2008..The authors evaluated the safety and efficacy of a formulation of phentolamine mesylate (PM) as a local anesthesia reversal agent for pediatric patients... - Balancing efficacy and safety in the use of oral sedation in dental outpatientsRaymond A Dionne
Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA
J Am Dent Assoc 137:502-13. 2006..Concerns about the safety of pediatric oral sedation and the incremental use of triazolam in adults prompted a workshop cosponsored by several professional organizations... - Drug interactions in dentistry: the importance of knowing your CYPsElliot V Hersh
University of Pennsylvania School of Dental Medicine, Philadelphia 19104 6030, USA
J Am Dent Assoc 135:298-311. 2004..The hepatic and intestinal cytochrome, or CY, P450 enzyme system is responsible for the biotransformation of a multitude of drugs. Certain medications used in dentistry can act as substrates, inducers or inhibitors of this system... - Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cellsSatish Devadas
Department of Molecular Genetics, Microbiology, and Immunology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
Immunity 25:237-47. 2006..GrB-deficient mice exhibited increased susceptibility to allergen-induced asthma. Thus, GrB plays a critical role in the TCR-ICD of Th2 cells... - Sedation for pediatric dental patientsMichael D Webb
Department of Pediatric Dentistry, Baylor College of Dentistry, USA
Dent Clin North Am 46:803-14, xi. 2002..By controlling disruptive behaviors, the pediatric dentist is able to provide quality dental care in an environment that is pleasant for the child, the parent, and the practitioner... - Adverse drug interactions involving common prescription and over-the-counter analgesic agentsElliot V Hersh
Department of Oral Surgery and Pharmacology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania 19104 6030, USA
Clin Ther 29:2477-97. 2007..In addition, an estimated 36 million Americans use over-the-counter (OTC) analgesics daily. Given this volume of use, it is not surprising that a number of drug interactions involving analgesic drugs have been reported... - Administering sedation: the controversy continuesPaul A Moore
Gen Dent 55:273-4; author reply 274. 2007 - Preemptive rofecoxib and dexamethasone for prevention of pain and trismus following third molar surgery *Paul A Moore
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:E1-7. 2005..The combination of preoperative rofecoxib 50 mg and intraoperative dexamethasone 10 mg was most effective in minimizing pain and trismus following third molar surgery...
Research Grants
- Microbiology/Immunology of Periodontal Disease in T1DMPaul Moore; Fiscal Year: 2002..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
- ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTSPaul Moore; Fiscal Year: 2003..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..