Research Topics
Species | Haijin MengSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomicsHaijin Meng
Department of Medicine, Cardiology Division, University of California Los Angeles, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 104:4530-5. 2007..Our results demonstrate the power of the integrative genomics in discovering causal genes and pathways underlying complex traits...
Disruption of the aortic elastic lamina and medial calcification share genetic determinants in miceSusanna S Wang
Department of Human Genetics, UCLA David Geffen School of Medicine, Los Angeles, CA, USA
Circ Cardiovasc Genet 2:573-82. 2009..Disruption of the elastic lamina, as an early indicator of aneurysm formation, and vascular calcification frequently occur together in atherosclerotic lesions of humans...
Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion modelImran N Mungrue
675 Charles E Young Dr S, MRL3210, Los Angeles, CA 90095
Arterioscler Thromb Vasc Biol 31:2806-12. 2011..The spectrum of PXE has been noted in Abcc6-deficient mice, including dystrophic cardiac calcification. We tested the role of Abcc6 in response to cardiac ischemia-reperfusion (I/R) injury...
A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J backgroundRichard C Davis
Department of Microbiology, Immunology and Molecular Genetics, Department of Medicine, and Department of Human Genetics, University of California, Los Angeles, CA 90095 1679, USA
Genomics 86:259-70. 2005..These 65 strains cover more than 95% of the autosomal genome and should facilitate the analysis of the many genetic trait differences that have been reported between these parental strains...
Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysisMichael R Garrett
Department of Physiology and Cardiovascular Genomics, Medical College of Ohio, Toledo 43614 5804, USA
Hypertension 45:451-9. 2005..Together, these results demonstrate that a BP QTL independent of Resp18 exists within the newly defined 117-kb QTL region on RNO9...
Localization of a blood pressure QTL to a 2.4-cM interval on rat chromosome 9 using congenic strainsHaijin Meng
Department of Physiology and Molecular Medicine, Medical College of Ohio, 3035 Arlington Avenue, Toledo 43614-5804, USA
Genomics 81:210-20. 2003..Ae3 mRNA was not differentially expressed in the kidney of congenic compared to S rats. Although the identity of the QTL remains unknown its map location has been reduced from an interval of 34.2 to 2.4 cM...
