R A Memon

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1
    R A Memon
    Departments of Medicine, University of California, San Francisco and the Metabolism Section, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Biol Chem 276:30118-26. 2001
  2. ncbi Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    J Lipid Res 42:452-9. 2001
  3. ncbi Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the li
    R A Memon
    Department of Medicine, University of California, San Francisco 94143, USA
    Endocrinology 141:4021-31. 2000
  4. ncbi Infection and inflammation induce LDL oxidation in vivo
    R A Memon
    Department of Medicine, University of California San Francisco, CA, USA
    Arterioscler Thromb Vasc Biol 20:1536-42. 2000
  5. ncbi Upregulation of uncoupling protein 2 mRNA in genetic obesity: lack of an essential role for leptin, hyperphagia, increased tissue lipid content, and TNF-alpha
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Biochim Biophys Acta 1484:41-50. 2000
  6. ncbi Down-regulation of liver and heart specific fatty acid binding proteins by endotoxin and cytokines in vivo
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Biochim Biophys Acta 1440:118-26. 1999
  7. ncbi In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response
    R A Memon
    Department of Medicine, University of California San Francisco CA 94143, USA
    Am J Physiol 277:R94-103. 1999
  8. ncbi Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice
    R A Memon
    Department of Medicine, University of California San Francisco, USA
    Diabetes 48:121-7. 1999
  9. ncbi Endotoxin and interleukin-1 decrease hepatic lipase mRNA levels
    K R Feingold
    Department of Medicine, University of California San Francisco, Department of Veterans Affairs Medical Center, 94121, USA
    Atherosclerosis 142:379-87. 1999
  10. ncbi Endotoxin, tumor necrosis factor, and interleukin-1 decrease hepatic squalene synthase activity, protein, and mRNA levels in Syrian hamsters
    R A Memon
    Department of Medicine, University of California San Francisco, and Department of Veterans Affairs Medical Center, 94121, USA
    J Lipid Res 38:1620-9. 1997

Collaborators

Detail Information

Publications12

  1. ncbi In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1
    R A Memon
    Departments of Medicine, University of California, San Francisco and the Metabolism Section, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Biol Chem 276:30118-26. 2001
    ..A decrease in bile acid synthesis in liver would reduce cholesterol catabolism and thereby contribute to the increase in hepatic lipoprotein production that is induced by LPS and cytokines...
  2. ncbi Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    J Lipid Res 42:452-9. 2001
    ..Memon, R. A., W. M. Holleran, Y. Uchida, A. H. Moser, C. Grunfeld, and K. R. Feingold. Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin. J. Lipid Res. 2001. 42: 452--459...
  3. ncbi Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the li
    R A Memon
    Department of Medicine, University of California, San Francisco 94143, USA
    Endocrinology 141:4021-31. 2000
    ..Taken together, our results suggest that the effects of PPAR-gamma activators on lipid metabolism and energy homeostasis in obesity and type 2 diabetes may be partly mediated through their effects on PPAR-gamma in the liver...
  4. ncbi Infection and inflammation induce LDL oxidation in vivo
    R A Memon
    Department of Medicine, University of California San Francisco, CA, USA
    Arterioscler Thromb Vasc Biol 20:1536-42. 2000
    ..Increased LDL oxidation during infection and inflammation may promote atherogenesis and could be a mechanism for increased incidence of coronary artery disease in patients with chronic infections and inflammatory disorders...
  5. ncbi Upregulation of uncoupling protein 2 mRNA in genetic obesity: lack of an essential role for leptin, hyperphagia, increased tissue lipid content, and TNF-alpha
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Biochim Biophys Acta 1484:41-50. 2000
    ..Taken together, these results suggest that the upregulation of UCP2 mRNA levels in the liver and WAT of ob/ob mice is not due to the lack of leptin, hyperphagia, increased tissue lipid content, or over-expression of TNF-alpha...
  6. ncbi Down-regulation of liver and heart specific fatty acid binding proteins by endotoxin and cytokines in vivo
    R A Memon
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Biochim Biophys Acta 1440:118-26. 1999
    ..The LPS-induced decrease in L-FABP and H-FABP may be an additional mechanism contributing to the decrease in FA oxidation that is associated with the host response to infection and inflammation...
  7. ncbi In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response
    R A Memon
    Department of Medicine, University of California San Francisco CA 94143, USA
    Am J Physiol 277:R94-103. 1999
    ..An increase in plasma PAF-AH may enhance the degradation of PAF as well as alter the structure and function of HDL during infection and inflammation...
  8. ncbi Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice
    R A Memon
    Department of Medicine, University of California San Francisco, USA
    Diabetes 48:121-7. 1999
    ....
  9. ncbi Endotoxin and interleukin-1 decrease hepatic lipase mRNA levels
    K R Feingold
    Department of Medicine, University of California San Francisco, Department of Veterans Affairs Medical Center, 94121, USA
    Atherosclerosis 142:379-87. 1999
    ..These changes may be initially beneficial to the host but if present for an extended period may be proatherogenic...
  10. ncbi Endotoxin, tumor necrosis factor, and interleukin-1 decrease hepatic squalene synthase activity, protein, and mRNA levels in Syrian hamsters
    R A Memon
    Department of Medicine, University of California San Francisco, and Department of Veterans Affairs Medical Center, 94121, USA
    J Lipid Res 38:1620-9. 1997
    ....
  11. ncbi Fatty acid synthesis in obese insulin resistant diabetic mice
    R A Memon
    Department of Medicine, University of California, San Francisco
    Horm Metab Res 26:85-7. 1994
    ..2 fold in ob/ob). FA synthesis was also increased in the liver of NIDDM (9 fold in db/db and 6 fold in ob/ob). These results provide further evidence that diabetes leads to changes in lipid metabolism in the SI...
  12. ncbi In vivo effects of interferon-alpha and interferon-gamma on lipolysis and ketogenesis
    R A Memon
    Department of Medicine, University of California, San Francisco
    Endocrinology 131:1695-702. 1992
    ..These data suggest that both IFNs exert a ketogenic effect by stimulating lipolysis, but at higher doses the ketogenic effect of IFN alpha is counteracted by its effect on hepatic FA synthesis...