Research Topics
| M Catherine McEllistremSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators
|
Detail Information
Publications
Detection of very high-level penicillin-resistant variants of the Tennessee (23 F)-4 clone via single and serial transformations with four serotype 19 A international pneumococcal clonesM Catherine McEllistrem
University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
Microb Drug Resist 11:271-8. 2005..Recombination within the MLST housekeeping genes was commonly detected in the transformants that had acquired penicillin resistance...- Acute otitis media due to penicillin-nonsusceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccineM Catherine McEllistrem
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
Clin Infect Dis 40:1738-44. 2005..The impact of the 7-valent pneumococcal conjugate vaccine (PCV7 [Prevnar]) on penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) recovered from children with acute otitis media (AOM) is unclear... - Erythromycin-nonsusceptible Streptococcus pneumoniae in children, 1999-2001M Catherine McEllistrem
University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
Emerg Infect Dis 11:969-72. 2005..The decline in infection rates was likely due to the pneumococcal 7-valent conjugate vaccine... - Marked increase in biofilm-derived rough pneumococcal variants and rifampin-resistant strains not due to hex gene mutationsM Catherine McEllistrem
University of Pittsburgh, Department of Medicine, Pittsburgh, Pennsylvania, USA
Microb Drug Resist 15:85-90. 2009..Taken together, these data suggest that mutations in the hex genes and modulation of hexA activity are unlikely to account for the generation of biofilm-derived rough variants... - Serotype 14 variants of the France 9V(-3) clone from Baltimore, Maryland, can be differentiated by the cpsB geneM Catherine McEllistrem
Infectious Diseases Epidemiology Research Unit, Division of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15229, USA
J Clin Microbiol 42:250-6. 2004..Although the correlation between serotype and the cpsB sequence was high, the overall diversity of the cpsB gene within a serotype likely will limit the role of this gene in a sequence-based serotyping method... - Locus-specific mutational events in a multilocus variable-number tandem repeat analysis of Escherichia coli O157:H7Anna C Noller
Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, 521 Parran Hall, 130 DeSoto St, Pittsburgh, PA 15261, USA
J Clin Microbiol 44:374-7. 2006..The remaining four loci had no slippage events detected. The mutation rates were locus specific and may impact the interpretation of MLVA data for epidemiologic investigations... - Pneumococcal resistance and serotype 19A in Pittsburgh-area children with acute otitis media before and after introduction of 7-valent pneumococcal polysaccharide vaccineAlejandro Hoberman
Division of General Academic Pediatrics, Children s Hospital of Pittsburgh of UPMC, 4401 Penn Ave, Pittsburgh, PA 15201, USA
Clin Pediatr (Phila) 50:114-20. 2011.... - Correlating epidemiologic trends with the genotypes causing meningococcal disease, MarylandM Catherine McEllistrem
University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania, USA
Emerg Infect Dis 10:451-6. 2004..The nonepidemic age-specific increases in serogroup C meningococcal infection in Maryland were clonal in nature and the changes in serogroup Y incidence were associated with a shift in the genotypes of strains causing invasive disease... - Characterization of in vitro biofilm-associated pneumococcal phase variants of a clinically relevant serotype 3 cloneM Catherine McEllistrem
Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA 15213 2582, USA
J Clin Microbiol 45:97-101. 2007..These in vitro phase variation data, which underscore the plasticity of the pneumococcus, need to be confirmed with in vivo analyses of the middle ear mucosa during otitis media... - Recurrent invasive pneumococcal disease in individuals with human immunodeficiency virus infectionM Catherine McEllistrem
Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
J Infect Dis 185:1364-8. 2002..Although a substantial proportion of recurrent pneumococcal infections was potentially preventable by vaccine, creating an effective vaccine may be challenging for this population... - Epidemiology of acute otitis media caused by Streptococcus pneumoniae before and after licensure of the 7-valent pneumococcal protein conjugate vaccineM Catherine McEllistrem
Division of Infectious Diseases, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania 15213-2582, USA
J Infect Dis 188:1679-84. 2003..In 1999 and 2001, 30.8% (4/13) and 26.1% (6/23) of the nonvaccine serogroups were implicated in capsular switching, respectively. Continued surveillance will be of great importance as the distribution of the PNC7 vaccine increases... - Multilocus variable-number tandem repeat analysis distinguishes outbreak and sporadic Escherichia coli O157:H7 isolatesAnna C Noller
Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Clin Microbiol 41:5389-97. 2003..In addition to being a simple and validated method for E. coli O157:H7 outbreak detection, MLVA appears to have a sensitivity equal to that of PFGE and a specificity superior to that of PFGE... - Distribution of penicillin-nonsusceptible pneumococcal clones in the Baltimore metropolitan area and variables associated with drug resistanceM Catherine McEllistrem
Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15213, USA
Clin Infect Dis 34:704-7. 2002.... - A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genesM Catherine McEllistrem
University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
Clin Infect Dis 40:265-72. 2005..The binary toxin genes cdt and cdtB have been detected in approximately 5% of Clostridium difficile strains. Severe C. difficile disease (CDD) may be associated with strains that carry the binary toxin genes... - Multilocus sequence typing reveals a lack of diversity among Escherichia coli O157:H7 isolates that are distinct by pulsed-field gel electrophoresisAnna C Noller
Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania, USA
J Clin Microbiol 41:675-9. 2003..E. coli O157:H7 has a striking lack of genetic diversity in the genes we explored, even among isolates that are clearly distinct by PFGE. Other approaches to identify improved molecular subtyping methods for E. coli 0157:H7 are needed... - Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Vaccine 26:1420-31. 2008..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations... - Pre- and postvaccination clonal compositions of invasive pneumococcal serotypes for isolates collected in the United States in 1999, 2001, and 2002Bernard Beall
Repsiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Mailstop C02, Atlanta, Georgia 30333, USA
J Clin Microbiol 44:999-1017. 2006..Continued genotypic surveillance is warranted, since certain clones not targeted by PCV7 are expanding, and their emergence as significant pathogens could occur with maintained vaccine pressure... - Geographic, demographic, and seasonal differences in penicillin-resistant Streptococcus pneumoniae in BaltimoreBernadette A Albanese
Department of International Health, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD, USA
Clin Infect Dis 34:15-21. 2002..The incidence of PRSP is increasing in Baltimore, and the seasonality of PRSP suggests that recent antibiotic use, which is more common in winter months, may rapidly affect the prevalence of resistant pneumococcal infections... - Clonal distribution of invasive pneumococcal isolates from children and selected adults in the United States prior to 7-valent conjugate vaccine introductionRobert E Gertz
Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:4194-216. 2003..In this work, we established the basic genetic structure within individual serotypes prior to PC7V use. The resultant database will be useful for detecting potential selective effects of this vaccine in postvaccine surveillance... - Emergence of a novel penicillin-nonsusceptible, invasive serotype 35B clone of Streptococcus pneumoniae within the United StatesBernard Beall
Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 186:118-22. 2002..The mosaic pbp2b and divergent ddl sequences were suggestive of interspecies recombination at the ddl-pbp2b chromosomal region... - Genotyping primers for fully automated multilocus variable-number tandem repeat analysis of Escherichia coli O157:H7Anna C Noller
J Clin Microbiol 42:3908. 2004