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Genomes and Genes | Rob McConnellSummaryAffiliation: University of Southern California Country: USA Publications
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Publications
Asthma in exercising children exposed to ozone: a cohort studyRob McConnell
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, CA 90089 9011, USA
Lancet 359:386-91. 2002..We investigated the relation between newly-diagnosed asthma and team sports in a cohort of children exposed to different concentrations and mixtures of air pollutants...- Dog ownership enhances symptomatic responses to air pollution in children with asthmaRob McConnell
Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA
Environ Health Perspect 114:1910-5. 2006..Experimental data suggest that asthma exacerbation by ambient air pollutants is enhanced by exposure to endotoxin and allergens; however, there is little supporting epidemiologic evidence... - Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort studyW James Gauderman
Department of Preventive Medicine, University of Southern California, 1540 Alcazar Street, Suite 220, Los Angeles, CA 90033, USA
Lancet 369:571-7. 2007..This study investigated the association between residential exposure to traffic and 8-year lung-function growth... - Ozone, oxidant defense genes, and risk of asthma during adolescenceTalat Islam
M D Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 177:388-95. 2008.... - The effect of air pollution on lung development from 10 to 18 years of ageW James Gauderman
Department of Preventive Medicine, University of Southern California, Los Angeles 90089, USA
N Engl J Med 351:1057-67. 2004..Whether exposure to air pollution adversely affects the growth of lung function during the period of rapid lung development that occurs between the ages of 10 and 18 years is unknown... - Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescenceTalat Islam
Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Thorax 65:139-45. 2010..Because nitrosative stress affects respiratory health, it was hypothesised that variants in NOS2A are associated with asthma incidence and lung function growth during adolescence... - Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health StudyJoshua Millstein
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
Arch Environ Health 59:505-14. 2004..07 [95%CI = 1.61-5.86]; OR = 1.31 [95%CI = 0.47-2.71]; respectively). The authors concluded that monthly variations in some ambient air pollutants were associated with monthly respiratory morbidity among school children... - Parental stress increases the detrimental effect of traffic exposure on children's lung functionTalat Islam
Department of Preventive Medicine, Keck School of Medicine, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 184:822-7. 2011..Emerging evidence indicates that psychosocial stress enhances the effect of traffic exposure on the development of asthma... - Childhood incident asthma and traffic-related air pollution at home and schoolRob McConnell
University of Southern California, Los Angeles, California, USA
Environ Health Perspect 118:1021-6. 2010..Traffic-related air pollution has been associated with adverse cardiorespiratory effects, including increased asthma prevalence. However, there has been little study of effects of traffic exposure at school on new-onset asthma... - Regular smoking and asthma incidence in adolescentsFrank D Gilliland
Department of Preventive Medicine, Keck School of Medicine of USC, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 174:1094-100. 2006.... - Traffic, susceptibility, and childhood asthmaRob McConnell
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Environ Health Perspect 114:766-72. 2006..These results indicate that residence near a major road is associated with asthma. The reason for larger effects in those with no parental history of asthma merits further investigation... - Bayesian modeling of air pollution health effects with missing exposure dataJohn Molitor
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
Am J Epidemiol 164:69-76. 2006..From these incomplete measures, long-term nitrogen dioxide exposure and its effect on health must be inferred. Results show that the method improves estimates when compared with standard frequentist approaches... - Childhood asthma and exposure to traffic and nitrogen dioxideW James Gauderman
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90089, USA
Epidemiology 16:737-43. 2005..Evidence for a causal relationship between traffic-related air pollution and asthma has not been consistent across studies, and comparisons among studies have been difficult because of the use of different indicators of exposure... - Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in childrenFrank D Gilliland
Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 166:457-63. 2002..Among children with GSTM1 (+) genotype, in utero exposure was not associated with asthma or wheezing. Our findings indicate that there are important long-term effects of in utero exposure in a genetically susceptible group of children... - Health effects of the 2003 Southern California wildfires on childrenNino Kunzli
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, School of Public Health, University of California, Los Angeles, CA, USA
Am J Respir Crit Care Med 174:1221-8. 2006..In late October 2003, Southern California wildfires burned more than 3,000 km2. The wildfires produced heavy smoke that affected several communities participating in the University of Southern California Children's Health Study (CHS)... - Prospective study of air pollution and bronchitic symptoms in children with asthmaRob McConnell
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 168:790-7. 2003.... - Rodent allergen in Los Angeles inner city homes of children with asthmaJill Berg
School of Nursing at the University of California, Los Angeles, Los Angeles, CA, USA
J Urban Health 85:52-61. 2008..Many of the predictors of rodent allergen are amenable to low-cost interventions that can be integrated with other measures to reduce exposure to indoor allergens... - TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absencesMade Wenten
Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine of USC, 1540 Alcazar Street, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 172:1563-8. 2005..The role of genetic susceptibility in risk for adverse effects from SHS has not been extensively investigated in children... - Predicting residential ozone deficits from nearby trafficRob McConnell
Department of Preventive Medicine, Keck School of Medicine at the University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90089, United States
Sci Total Environ 363:166-74. 2006..These findings may have implications for studies of health effects of traffic-related pollutants... - Ethnic differences in the effect of asthma on pulmonary function in childrenYue Zhang
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
Am J Respir Crit Care Med 183:596-603. 2011..The impact of asthma on chronic lung function deficits is well known. However, there has been little study of ethnic differences in these asthma-associated deficits... - Relationship between air pollution, lung function and asthma in adolescentsTalat Islam
Department of Preventive Medicine, Keck School of Medicine, Los Angeles, California 90033, USA
Thorax 62:957-63. 2007..A study was undertaken to determine whether lung function is associated with new onset asthma and whether this relationship varies by exposure to ambient air pollutants... - Obesity and the risk of newly diagnosed asthma in school-age childrenFrank D Gilliland
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Am J Epidemiol 158:406-15. 2003..77, 95% CI: 1.26, 2.49) than in allergic children (RR = 1.16, 95% CI: 0.63, 2.15). The authors conclude that being overweight is associated with an increased risk of new-onset asthma in boys and in nonallergic children... - Use of an electrostatic dust cloth for self-administered home allergen collectionWendy Cozen
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089 9175, United States of America
Twin Res Hum Genet 11:150-5. 2008.... - Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthmaMuhammad T Salam
Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Am J Respir Crit Care Med 176:1192-9. 2007..Tobacco smoke and traffic emissions induce airway inflammation and modulate TGF-beta1 gene expression. We hypothesized that the effects of functional TGF-beta1 variants on asthma occurrence vary by these exposures... - Parental stress and childhood wheeze in a prospective cohort studyJoel Milam
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
J Asthma 45:319-23. 2008..Although studies indicate that psychological stress is linked with asthma morbidity, it is unknown whether stress is associated with the incidence of asthma symptoms... - Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intakeFrank D Gilliland
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Am J Epidemiol 158:576-84. 2003..In summary, lung function levels were lower in children with inadequate dietary antioxidant vitamin intake... - Residential proximity to freeways and autism in the CHARGE studyHeather E Volk
Department of Preventive Medicine, Zilkha Neurogenetic Institute, Keck School of Medicine, Children s Hospital Los Angeles, University of Southern California, Los Angeles, California 90033, USA
Environ Health Perspect 119:873-7. 2011..Traffic-related air pollution, a common exposure with established effects on these pathways, contains substances found to have adverse prenatal effects... - Breathless in Los Angeles: the exhausting search for clean airNino Kunzli
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
Am J Public Health 93:1494-9. 2003..We describe these findings and urge a more aggressive effort to reduce air pollution exposures to protect our children's health. Lessons from this "case study" have national implications... - Indoor risk factors for asthma in a prospective study of adolescentsRob McConnell
Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
Epidemiology 13:288-95. 2002..However, there has been little investigation of the effect of the indoor environment on incident asthma in adolescents... - Asthma and school commuting timeRob McConnell
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Occup Environ Med 52:827-8. 2010..This study examined associations of asthma with school commuting time... - Association between air pollution and lung function growth in southern California children: results from a second cohortW James Gauderman
Department of Preventive Medicine, University of Southern California, Los Angeles 90033, USA
Am J Respir Crit Care Med 166:76-84. 2002.... - Cockroach counts and house dust allergen concentrations after professional cockroach control and cleaningRob McConnell
Department of Preventive Medicine, Keck School of Medicine at the University of Southern California, Los Angeles, California 90033, USA
Ann Allergy Asthma Immunol 91:546-52. 2003..However, there have been few studies of interventions to reduce exposures in this setting... - Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school childrenFrank D Gilliland
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90053, USA
Am J Respir Crit Care Med 166:346-51. 2002..80; 95% confidence interval, 0.65-0.99). GSTM1 and T1 genotypes were not associated with respiratory illness. We conclude that GSTP1 genotype influences the risk or severity of respiratory infections in school-aged children... - Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention ResearchFrank Gilliland
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Environ Health Perspect 113:1447-54. 2005..If these lessons are applied, the National Children's Study offers a unique opportunity to assess the adverse effects of air pollution on interrelated health outcomes during the critical early life period... - Competing definitions of contextual environmentsZaria Tatalovich
Department of Geography, University of Southern California, Los Angeles, California 90089 0255, USA
Int J Health Geogr 5:55. 2006..The sensitivity of census variable estimates to the choice of community boundaries and weights was assessed using standard tests of significance... - Knowledge of skin test results among parents of asthmatic childrenJean L Richardson
Department of Preventive Medicine, Keck School of Medicine at the University of Southern California, Los Angeles, California 90033, USA
J Asthma 41:199-204. 2004..If parents are ill-informed of the specific allergen sensitivity of their children, they may be unable to take the necessary steps to minimize exposure... - Mode of delivery is associated with asthma and allergy occurrences in childrenMuhammad T Salam
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Ann Epidemiol 16:341-6. 2006..CONCLUSION: We conclude that birth by C-section or processes associated with it may increase the risk for atopic disease in childhood... - Associations of place of birth with asthma and wheezing in Mexican American childrenKamal Eldeirawi
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, IL 60612 7260, USA
J Allergy Clin Immunol 116:42-8. 2005..There are wide global variations in the prevalence of asthma and wheezing... - Assessing uncertainty in spatial exposure models for air pollution health effects assessmentJohn Molitor
Department of Epidemiology and Public Health, Imperial College London, London, UK
Environ Health Perspect 115:1147-53. 2007..Although numerous epidemiologic studies now use models of intraurban exposure, there has been little systematic evaluation of the performance of different models... - Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurementMichael Jerrett
School of Public Health, Division of Environmental Health Science, University of California, Berkeley, California 94720 7360, USA
Environ Health Perspect 116:1433-8. 2008..The question of whether air pollution contributes to asthma onset remains unresolved... - Lessons Learned for the Study of Childhood Asthma from the Centers for Children's Environmental Health and Disease Prevention ResearchPeyton A Eggleston
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Environ Health Perspect 113:1430-6. 2005..Medications confounded the definition of asthma disease activity, and must be repeatedly and systematically estimated. Despite these many challenges, the Children's Centers successfully conducted long-term studies of asthma... - An attributable risk model for exposures assumed to cause both chronic disease and its exacerbationsNino Kunzli
Institucio Catalana de Recerca i Estudis Avancats, Barcelona, Spain
Epidemiology 19:179-85. 2008..For exposures affecting both the development of chronic disease and its exacerbation, the usual methods to derive attributable risks (AR) are inappropriate... - Long-term neurobehavioral effects of mild poisonings with organophosphate and n-methyl carbamate pesticides among banana workersCatharina Wesseling
Universidad Nacional, Heredia, Costa Rica
Int J Occup Environ Health 8:27-34. 2002..Workers with histories of poisoning may be more susceptible to neurobehavioral effects with subsequent exposures... - Tactile vibration thresholds after acute poisonings with organophosphate insecticidesJamilette Miranda
Department of Physiology, National Autonomous University, Leon, Nicaragua
Int J Occup Environ Health 8:212-9. 2002..The development of threshold impairment as a consequence of severe intentional poisonings with neuropathic OPs is consistent with other reports indicating that only severe OP poisonings produce sensory peripheral nerve effects...