Research Topics
| Bradley MarpleSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
Competency-based resident educationBradley F Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas, Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9035, USA
Otolaryngol Clin North Am 40:1215-25, vi-vii. 2007..This article is a brief overview of current efforts to achieve this goal...
Safety review of benzalkonium chloride used as a preservative in intranasal solutions: an overview of conflicting data and opinionsBradley Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, 75390, USA
Otolaryngol Head Neck Surg 130:131-41. 2004..However, over the past several years there have been conflicting reports of damage to human nasal epithelia and/or exacerbation of rhinitis medicamentosa associated with intranasal products containing BKC...
Keys to successful management of patients with allergic rhinitis: focus on patient confidence, compliance, and satisfactionBradley F Marple
University of Texas Southwestern Medical School, Dallas, TX 75390 7208, USA
Otolaryngol Head Neck Surg 136:S107-24. 2007..CONCLUSIONS: Health care providers must gain a greater understanding of patient expectations to increase medication compliance and patient satisfaction and confidence...
Allergy and the contemporary rhinologistBradley F Marple
Department of Otolaryngology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9035, USA
Otolaryngol Clin North Am 36:941-55. 2003..Instead, to be most effective, rhinologists must synthesize diagnostic and treatment plans, using all aspects of this field of medicine...
American Academy of Otolaryngic Allergy CME report: allergy; scope of knowledgeBradley F Marple
Department of Otolaryngology, Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390-9035, USA
Otolaryngol Head Neck Surg 136:8-10. 2007
Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trialBradley F Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Clin Ther 29:2690-8. 2007..The speed with which patients experience resolution of ABRS symptoms has not been reported...
Targeting congestion in allergic rhinitis: the importance of intranasal corticosteroidsBradley F Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9035, USA
Allergy Asthma Proc 29:232-40. 2008..Pretreatment with INSs has been shown to relieve early and late-phase clinical symptoms of AR. Modification of the disease process results in significant relief of symptoms and leads to fewer disease exacerbations...
Going to the next level: health care's evolving expectations for evidenceBradley F Marple
Department of Otolaryngology, Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9035, USA
Otolaryngol Head Neck Surg 141:551-4. 2009..It has become the responsibility of the organized medical profession to play a role in influencing and supporting production of high-quality outcomes research...
Natural history of allergic fungal rhinosinusitis: a 4- to 10-year follow-upBradley Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390, USA
Otolaryngol Head Neck Surg 127:361-6. 2002..Short-term studies have revealed varying recurrence rates based on therapy; however, little is currently known about the long-term natural history of the disease...
Diagnosis and management of chronic rhinosinusitis in adultsBradley F Marple
UT Southwestern Medical Center, Department of Otolaryngology Head and Neck Surgery, Dallas, TX 75390 7208, USA
Postgrad Med 121:121-39. 2009....
Azithromycin extended release vs amoxicillin/clavulanate: symptom resolution in acute sinusitisBradley F Marple
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Am J Otolaryngol 31:1-8. 2010..The aim of the study was to compare early symptom resolution with a single 2-g dose of azithromycin extended release or 10 days of amoxicillin/clavulanate 875 mg/125 mg every 12 hours in patients with acute sinusitis...
Acute bacterial rhinosinusitis: a review of U.S. treatment guidelinesBradley F Marple
University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9035, USA
Otolaryngol Head Neck Surg 135:341-8. 2006..This article provides an overview of current U.S. guidelines for the treatment of ABRS, focusing on the impact of antibiotic resistance on treatment options...
Editorial commentary: dilemma in trial design: do current study designs adequately evaluate effectiveness antibiotic in ABRS?Bradley F Marple
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Otolaryngol Head Neck Surg 133:200-1. 2005
Rhinologic pharmacotherapy in rhinoplastyC Spencer Cochran
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9035, USA
Facial Plast Surg Clin North Am 12:415-24, v-vi. 2004..A thorough medical history and examination elucidate sinonasal disease conditions that may not improve after septorhinoplasty but potentially could respond to pharmacologic therapy...
Olopatadine nasal spray for the treatment of allergic rhinitisPeter S Roland
Department of Otolaryngology, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9035, USA
Expert Rev Clin Immunol 6:197-204. 2010..With an onset of action of 30 min, olopatadine nasal spray has also been shown to improve quality of life, ability to perform work and the conduct of usual activities in SAR patients...
Balloon catheter technology in rhinology: Reviewing the evidencePete S Batra
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Laryngoscope 121:226-32. 2011..The frank strengths and weaknesses of the peer-reviewed literature will be highlighted. The potential complications unique to balloon catheters and radiation exposure from fluoroscopy will also be discussed...
The role of fungi in chronic rhinosinusitisAmber Luong
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Otolaryngol Clin North Am 38:1203-13. 2005..As investigation focusing upon these new concepts continues, it should lead to better understanding of chronic inflammatory disease of the respiratory tracts...
Techniques of intranasal steroid useMichael S Benninger
Department of Otolaryngology Head and Neck Surgery, Henry Ford Hospital, Detroit, Michigan 48202, USA
Otolaryngol Head Neck Surg 130:5-24. 2004..To determine whether the technique used affects the efficacy and safety of the product, this review of evidence had the goal of identifying and establishing a preferred method of applying INS sprays...
Clinical practice guideline: adult sinusitisRichard M Rosenfeld
Department of Otolaryngology, SUNY Downstate Medical Center and Long Island College Hospital, Brooklyn, NY 11201 5514, USA
Otolaryngol Head Neck Surg 137:S1-31. 2007..This guideline is intended for all clinicians who are likely to diagnose and manage adults with sinusitis...
Fungal rhinosinusitis: state-of-the-art diagnosis and treatmentRobert Todd Adelson
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390-9035, USA
J Otolaryngol 34:S18-23. 2005..We review the classification of the various forms of fungal rhinosinusitis and their clinical presentations, radiologic findings, and treatment options...
Sinus surgery: indications and techniquesAmber Luong
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA
Clin Rev Allergy Immunol 30:217-22. 2006..This article reviews the indications of sinus surgery. In addition, it addresses some of the controversies, limitations, and advances in FESS...
Effect of topical nasal steroid sprays on nasal mucosa and ciliary functionD J Verret
Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9035, USA
Curr Opin Otolaryngol Head Neck Surg 13:14-8. 2005..The purpose of this article is to review current literature addressing the effects of the components of local intranasal steroid sprays on the structure and function of the nasal mucosa...
Allergic fungal rhinosinusitisAmber Luong
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Curr Allergy Asthma Rep 4:465-70. 2004..In this article, we review current data and theories regarding the pathophysiology and clinical presentation of AFRS, as well as the roles of various surgical and nonsurgical forms of therapy...
Skull base cerebrospinal fluid fistulas: a comprehensive diagnostic algorithmJeffrey S Zapalac
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390, USA
Otolaryngol Head Neck Surg 126:669-76. 2002....
The safety of intranasal steroidsMichael S Benninger
Department of Otolaryngology Head and Neck Surgery, Henry Ford Health System, Detroit, MI 48202, USA
Otolaryngol Head Neck Surg 129:739-50. 2003..An extensive review of the literature overwhelmingly supports the assertion that intranasal steroids are safe in prescribed doses and should allay the misconceptions regarding their appropriate use in the management of allergic rhinitis...
Allergic fungal rhinosinusitis: diagnosis and managementMatthew W Ryan
Department of Otolaryngology, The University of Texas Medical Branch, Galveston, Texas 77555 0521, USA
Curr Opin Otolaryngol Head Neck Surg 15:18-22. 2007..The proper diagnosis and treatment of allergic fungal rhinosinusitis remain controversial. We discuss recent additions to the literature regarding diagnosis and treatment of this condition...
The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgeryTijani Issioui
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9068, USA
Anesth Analg 94:1188-93, table of contents. 2002..However, acetaminophen (2000 mg) or celecoxib (200 mg) alone was not significantly more effective than placebo in reducing postoperative pain...
Optimal duration of allergic rhinitis clinical trialsJohn H Krouse
Department of Otolaryngology Head and Neck Surgery, Wayne State University, Detroit, MI 48201, USA
Otolaryngol Head Neck Surg 133:467-87; discussion 488. 2005..Therefore, we performed an evidence-based review to answer the clinical question, What is the optimal duration for SAR and PAR clinical trials?..
Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitisEli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 95:600-6. 2005..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
An assessment of the onset and duration of action of olopatadine nasal sprayPiyush Patel
Allied Research International, Mississauga, ON, Canada
Otolaryngol Head Neck Surg 137:918-24. 2007..Seasonal allergic rhinitis (SAR) is a highly prevalent disease. This study was conducted to evaluate the onset and duration of action of three concentrations of olopatadine nasal spray...
Rhinosinusitis: establishing definitions for clinical research and patient careEli O Meltzer
Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
J Allergy Clin Immunol 114:155-212. 2004
The impact/role of asthma in otolaryngologyHarold C Pillsbury
Otolaryngol Head Neck Surg 136:157. 2007
Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgeryTijani Issioui
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, 75390-9068, USA
Anesthesiology 97:931-7. 2002..CONCLUSIONS: Rofecoxib, 50 mg administered orally, decreased postoperative pain and the need for analgesic rescue medication after otolaryngologic surgery. The addition of 2 g oral acetaminophen failed to improve its analgesic efficacy...
Dry mouth and nose in the older patient. What every PCP should knowBenjamin A Bassichis
Department of Otolaryngology-Head and Neck Surgery, University of Illinois at Chicago, USA
Geriatrics 57:22-4, 29, 32 passim. 2002..Management of dry mouth includes hydration and use of mouthwash, sugarless gum, candy, and saliva substitutes. Dry nose can be managed with nasal sprays that moisten the nasal cavity...
Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiologyMichael S Benninger
Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, MI 48202, USA
Otolaryngol Head Neck Surg 129:S1-32. 2003
Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis to mountain cedarPaul H Ratner
Sylvana Research, San Antonio, Texas 78229, USA
Ann Allergy Asthma Immunol 95:474-9. 2005..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR) to mountain cedar...
Rhinosinusitis: developing guidance for clinical trialsEli O Meltzer
Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
J Allergy Clin Immunol 118:S17-61. 2006....
Rhinosinusitis: Developing guidance for clinical trialsEli O Meltzer
Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
Otolaryngol Head Neck Surg 135:S31-80. 2006....
Minor recurrent epistaxis: prevalence and a new method for managementMichael S Benninger
Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, Michigan, USA
Otolaryngol Head Neck Surg 131:317-20. 2004
Rhinosinusitis: Establishing definitions for clinical research and patient careEli O Meltzer
Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
Otolaryngol Head Neck Surg 131:S1-62. 2004
