Research Topics
| Karen E MarkSummaryAffiliation: University of Washington Country: USA Publications
Research Grants
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Detail Information
Publications
Gonorrhea surveillance: estimating epidemiologic and clinical characteristics of reported cases using a sample survey methodologyKaren E Mark
Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Sex Transm Dis 31:215-20. 2004..Knowing the proportion of reported gonorrhea cases identified through screening, the diagnostic test used, and patient behavioral risk factors might help to better explain changes in gonorrhea rates over time...
Rapidly cleared episodes of herpes simplex virus reactivation in immunocompetent adultsKaren E Mark
Department of Medicine, University of Washington, Seattle, Washington 98122, USA
J Infect Dis 198:1141-9. 2008..Recent in situ data show the localization of HSV-specific CD8(+) T cells at the dermal epidermal junction next to peripheral sensory nerve endings, suggesting that viral reactivation may occur more frequently than previously appreciated...
Internet and email use among STD clinic patientsKaren E Mark
Department of Medicine, University of Washington, Seattle, Washington 98122, USA
Sex Transm Dis 35:960-5. 2008..Little data exist on Internet and email use among STD clinic patients for research and clinical care communication...
Topical resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trialKaren E Mark
Department of Medicine, University of Washington, Seattle, WA 98104, USA
J Infect Dis 195:1324-31. 2007..In animal models, induction of Th1-specific responses modifies experimental herpes simplex virus (HSV) infection...
Medical care and alcohol use after testing hepatitis C antibody positive at STD clinic and HIV test site screening programsKaren E Mark
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA
Public Health Rep 122:37-43. 2007..The purpose of this study was to assess rates of medical evaluation and HCV treatment, change in alcohol consumption, and barriers to medical care after testing anti-HCV positive through a public screening program...
Targeted prenatal herpes simplex virus testing: can we identify women at risk of transmission to the neonate?Karen E Mark
Department of Medicine, University of Washington, Seattle, WA, USA
Am J Obstet Gynecol 194:408-14. 2006..The cost-effectiveness of these interventions would be improved if high-risk pregnancies could be easily identified for targeted testing...
Rapidly cleared episodes of oral and anogenital herpes simplex virus shedding in HIV-infected adultsKaren E Mark
Department of Medicine, University of Washington, Seattle, WA, USA
J Acquir Immune Defic Syndr 54:482-8. 2010..To determine whether rapidly cleared episodes of herpes simplex virus (HSV) reactivation occur in HIV-infected adults...
Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodesJoshua T Schiffer
Department of Medicine, Laboratory Medicine, Global Health Medicine, University of Washington, Seattle, WA 98195, USA
Proc Natl Acad Sci U S A 107:18973-8. 2010..The model suggests that the rate of containment of infected cells by the peripheral mucosal immune system is the major driver of duration and severity of HSV-2 reactivation in the immunocompetent host...
Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical modelJoshua T Schiffer
Department of Medicine, University of Washington, Seattle, WA 98195, USA
Sci Transl Med 1:7ra16. 2009..Frequent HSV-2 shedding episodes in humans are explained by nearly constant release of small numbers of viruses from neurons that terminate in the genital tract...
Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study)Ruanne V Barnabas
Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Acquir Immune Defic Syndr 57:238-44. 2011..To explore these relationships, we examined the impact of preexisting HSV-2 infection in an international HIV vaccine trial...
Contraception among HIV concordant and discordant couples in Zambia: a randomized controlled trialKaren E Mark
Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA
J Womens Health (Larchmt) 16:1200-10. 2007..This study examines the impact of an intervention to promote dual-method contraceptive use among HIV concordant and discordant couples already using condoms for HIV prevention...
Prevalence of and associated risk factors for fluoroquinolone-resistant Neisseria gonorrhoeae in California, 2000-2003Heidi M Bauer
California Department of Health Services Sexually Transmitted Disease Control Branch, Oakland, CA, USA
Clin Infect Dis 41:795-803. 2005..Rates of fluoroquinolone-resistant Neisseria gonorrhoeae (QRNG) are increasing worldwide and in California...
Research Grants
- Effect of Suppressive Therapy on Behavioral Determinants of HSV-2 TransmissionKAREN MARK; Fiscal Year: 2007....
