Research Topics
| Osvaldo MarinottiSummaryAffiliation: University of California Country: USA Publications
| Collaborators
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Detail Information
Publications
Spatial mapping of gene expression in the salivary glands of the dengue vector mosquito, Aedes aegyptiJennifer Juhn
Department of Molecular Biology and Biochemistry, University of California, Irvine, USA
Parasit Vectors 4:1. 2011....
Complete mtDNA genomes of Anopheles darlingi and an approach to anopheline divergence timeMarta Moreno
Griffin Laboratory, New York State Department of Health, Wadsworth Center, 5668 State Farm Road, Slingerlands, NY 12159, USA
Malar J 9:127. 2010....
The salivary gland transcriptome of the neotropical malaria vector Anopheles darlingi reveals accelerated evolution of genes relevant to hematophagyEric Calvo
Section of Vector Biology, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852, USA
BMC Genomics 10:57. 2009..Here we present and analyze data from a comprehensive salivary gland (SG) transcriptome of the neotropical malaria vector Anopheles darlingi (subgenus Nyssorhynchus)...
aeGEPUCI: a database of gene expression in the dengue vector mosquito, Aedes aegyptiSumudu N Dissanayake
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
BMC Res Notes 3:248. 2010....
Microarray analysis of genes showing variable expression following a blood meal in Anopheles gambiaeO Marinotti
Department of Molecular Biology and Biochemistry, University of California, Irvine, 92697, USA
Insect Mol Biol 14:365-73. 2005..The microarray data and an electronic hyperlinked version of all tables are available to the research community at http://www.angagepuci.bio.uci.edu/1/...
Genetic control of malaria parasite transmission: threshold levels for infection in an avian model systemNijole Jasinskiene
Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697 3900, USA
Am J Trop Med Hyg 76:1072-8. 2007..We conclude that similar endpoints must be reached with human pathogens if we are to expect an effect on disease transmission...
RNA-seq analyses of blood-induced changes in gene expression in the mosquito vector species, Aedes aegyptiMariangela Bonizzoni
Department of Molecular Biology and Biochemistry, University of California, Irvine, California, USA
BMC Genomics 12:82. 2011..The mosquito Aedes aegypti (Diptera, Culicidae), a vector of Dengue viruses, Yellow Fever Virus (YFV) and Chikungunya virus (CV), is the subject of this study to look at genome-wide changes in gene expression following a blood meal...
Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensiAlison T Isaacs
Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States of America
PLoS Pathog 7:e1002017. 2011..Transgenic mosquito lines expressing each of the scFv genes had significantly lower infection levels than controls when challenged with P. falciparum...
Structure and expression of the lipophorin-encoding gene of the malaria vector, Anopheles gambiaeOsvaldo Marinotti
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900, USA
Comp Biochem Physiol B Biochem Mol Biol 144:101-9. 2006..An elevated transcriptional activity of the lipophorin gene during vitellogenesis is consistent with the presence of putative cis-regulatory elements (GATA and ecdysone responsive elements) in its 3'-end flanking DNA sequence...
Functional characterization of the promoter of the vitellogenin gene, AsVg1, of the malaria vector, Anopheles stephensiXavier Nirmala
Department of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697 3900, USA
Insect Biochem Mol Biol 36:694-700. 2006..These data indicate that the AsVg1 promoter is a good candidate for controlling the expression of anti-pathogen effector molecules in this malaria vector mosquito...
Comparative genomics allows the discovery of cis-regulatory elements in mosquitoesDouglas H Sieglaff
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
Proc Natl Acad Sci U S A 106:3053-8. 2009..These results validate the methodology and support a relationship between the discovered motifs and the conservation of hematophagy in mosquitoes...
Genome-wide analysis of gene expression in adult Anopheles gambiaeO Marinotti
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900, USA
Insect Mol Biol 15:1-12. 2006..uci.edu/) has been made available so that detailed analyses of specific groups of genes based on their descriptions, functions or levels of gene expression variation can be performed by interested investigators according to their needs...
angaGEDUCI: Anopheles gambiae gene expression database with integrated comparative algorithms for identifying conserved DNA motifs in promoter sequencesSumudu N Dissanayake
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
BMC Genomics 7:116. 2006....
Proteomics reveals novel components of the Anopheles gambiae eggshellDolphine A Amenya
Program in Public Health, University of California, Irvine, CA 92697, USA
J Insect Physiol 56:1414-9. 2010..This analysis fills a considerable gap of knowledge about proteins that build the eggshell of anopheline mosquitoes...
Molecular genetic manipulation of vector mosquitoesOlle Terenius
Department of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697, USA
Cell Host Microbe 4:417-23. 2008..We discuss how this information may be exploited for the optimization of transgenes that interfere with the propagation and development of pathogens in their mosquito hosts...
Expression patterns of the larval and adult hexamerin genes of Musca domesticaM L Capurro
Departamento de Bioquimica, Instituto de Quimica, Universidade de Sao Paulo, Brasil
Insect Mol Biol 9:169-77. 2000..Genomic analyses showed that the larval hexamerin and female hexamerin genes from M. domestica belong to two distinct multigenic families...
Gene structure and expression of nanos (nos) and oskar (osk) orthologues of the vector mosquito, Culex quinquefasciatusJ Juhn
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
Insect Mol Biol 17:545-52. 2008..Hybridization in situ analyses reveal differences in mRNA distribution in early embryos in comparison with the cyclorraphan, Drosophila melanogaster, highlighting a possible feature in the divergence of the clades each insect represents...
16S rRNA gene sequences from bacteria associated with adult Anopheles darlingi (Diptera: Culicidae) mosquitoesOlle Terenius
Department of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697, USA
J Med Entomol 45:172-5. 2008..The 16S sequences of bacteria recovered, include some closely related to those found in other vector mosquitoes, including Aeromonas, Pantoea and Pseudomonas species...
Nanos (nos) genes of the vector mosquitoes, Anopheles gambiae, Anopheles stephensi and Aedes aegyptiEric Calvo
Department of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697-3900, USA
Insect Biochem Mol Biol 35:789-98. 2005..These features make nos genes promising candidates for donating control sequences to modified transposons...
The accumulation of specific mRNAs following multiple blood meals in Anopheles gambiaeX Nirmala
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900, USA
Insect Mol Biol 14:95-103. 2005..The multiple feeding behaviour of An. gambiae thus can be an advantage to express high levels of antiparasite effector molecules to counteract the parasites throughout most of adult development...
Comparative fitness assessment of Anopheles stephensi transgenic lines receptive to site-specific integrationD A Amenya
Program in Public Health, University of California, Irvine, CA 92697 3900, USA
Insect Mol Biol 19:263-9. 2010..These transgenic lines are suitable for future site-specific integrations of antiparasite transgenes into the attP sites...
The transcriptome of adult female Anopheles darlingi salivary glandsE Calvo
University of California, Irvine, Department of Molecular Biology and Biochemistry, Irvine, CA 92697-3900, USA
Insect Mol Biol 13:73-88. 2004..Tabular and supplementary material containing the cDNA sequences and annotations are available at http://www.ncbi.nlm.nih.gov/projects/Mosquito/A_darlingi_sialome/..
Amazonian malaria vector anopheline relationships interpreted from ITS2 rDNA sequencesM T Marrelli
Departamento de Parasitologia, , Universidade de Sao Paulo, Sao Paulo, Brazil
Med Vet Entomol 19:208-18. 2005..These ITS2 sequence data proved to be a useful tool for species identification and, potentially, to solve taxonomic problems...
Analysis of the wild-type and mutant genes encoding the enzyme kynurenine monooxygenase of the yellow fever mosquito, Aedes aegyptiQ Han
Department of Pathobiology, University of Illinois at Urbana-Champaign, IL, USA
Insect Mol Biol 12:483-90. 2003..Recombinant Ae. aegypti KMO showed high substrate specificity for kynurenine with optimum activity at 40 degrees C and pH = 7.5. Kinetic parameters and inhibition of KMO activity by Cl- and pyridoxal-5-phosphate were determined...
Primary characterization and basal promoter activity of two hexamerin genes of Musca domesticaC K Moreira
Dept. de Parasitologia, , ICB, , SP, 05508-900, Brazil
J Insect Sci 4:2. 2004..The constructs were assayed in vitro in transfected S2 Drosophila melanogaster cells demonstrating that the cloned M. domestica DNA fragments exhibit promoter activity...
