Morris F Maduro

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Knockdown of SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification in C. briggsae as compared with C. elegans
    Katy Tan Hui Lin
    Department of Biology, University of California, Riverside, Riverside, CA 92521, USA
    Dev Biol 325:296-306. 2009
  2. ncbi The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development
    Gina Broitman-Maduro
    Department of Biology, University of California, Riverside, CA 92521, USA
    Development 136:2735-46. 2009
  3. ncbi Structure and evolution of the C. elegans embryonic endomesoderm network
    Morris F Maduro
    Department of Biology, University of California, Riverside, CA 92521, USA
    Biochim Biophys Acta 1789:250-60. 2009
  4. ncbi Cell fate specification in the C. elegans embryo
    Morris F Maduro
    Department of Biology, University of California, Riverside, Riverside, California 92521, USA
    Dev Dyn 239:1315-29. 2010
  5. ncbi Maternal deployment of the embryonic SKN-1-->MED-1,2 cell specification pathway in C. elegans
    Morris F Maduro
    Department of Biology, 3380 Spieth Hall, University of California, Riverside, Riverside, CA 92521, USA
    Dev Biol 301:590-601. 2007
  6. ncbi The noncanonical binding site of the MED-1 GATA factor defines differentially regulated target genes in the C. elegans mesendoderm
    Gina Broitman-Maduro
    Department of Biology and Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California 93106, USA
    Dev Cell 8:427-33. 2005
  7. ncbi Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network
    Melissa Owraghi
    Department of Biology, University of California, 2121A Genomics Building, Riverside, Riverside, CA 92521, USA
    Dev Biol 340:209-21. 2010
  8. ncbi Genetic redundancy in endoderm specification within the genus Caenorhabditis
    Morris F Maduro
    Department of Molecular, Cellular and Developmental Biology and Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA
    Dev Biol 284:509-22. 2005
  9. ncbi Med-type GATA factors and the evolution of mesendoderm specification in nematodes
    Cristian Coroian
    Department of Biology, UC Riverside, 3380 Spieth Hall, Riverside, CA 92521, USA
    Dev Biol 289:444-55. 2006
  10. ncbi Specification of the C. elegans MS blastomere by the T-box factor TBX-35
    Gina Broitman-Maduro
    Department of Biology, University of California, Riverside, Riverside, CA 92521, USA
    Development 133:3097-106. 2006

Research Grants

  1. Specification of embryonic C. elegans mesoderm by a T-box factor
    Morris Maduro; Fiscal Year: 2007

Collaborators

  • JOEL ROTHMAN
  • Paul W Sternberg
  • Rueyling Lin
  • Serena Cervantes
  • Gina Broitman-Maduro
  • Melissa Owraghi
  • Wendy W K Hung
  • Katy Tan Hui Lin
  • Erica M Sommermann
  • Cristian Coroian
  • Kyunghee Koh
  • Keith R Strohmaier
  • Heather Roberson
  • Thomas Luu
  • Steven Kuntz
  • Katy Tan-Hui Lin
  • Cricket G Wood
  • Sara M Peyrot
  • David M Eisenmann
  • Javier A Wagmaister

Detail Information

Publications17

  1. ncbi Knockdown of SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification in C. briggsae as compared with C. elegans
    Katy Tan Hui Lin
    Department of Biology, University of California, Riverside, Riverside, CA 92521, USA
    Dev Biol 325:296-306. 2009
    ..Our results suggest that integration of Wnt-dependent and Wnt-independent cell fate specification pathways within the Caenorhabditis genus can occur in different ways...
  2. ncbi The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development
    Gina Broitman-Maduro
    Department of Biology, University of California, Riverside, CA 92521, USA
    Development 136:2735-46. 2009
    ..elegans to specify a major precursor of mesoderm...
  3. ncbi Structure and evolution of the C. elegans embryonic endomesoderm network
    Morris F Maduro
    Department of Biology, University of California, Riverside, CA 92521, USA
    Biochim Biophys Acta 1789:250-60. 2009
    ..Overall, the complexities of C. elegans endomesoderm specification build a picture of a network that is robust, complex, and still evolving...
  4. ncbi Cell fate specification in the C. elegans embryo
    Morris F Maduro
    Department of Biology, University of California, Riverside, Riverside, California 92521, USA
    Dev Dyn 239:1315-29. 2010
    ..In this review, the C. elegans embryo is considered as a model system for studies of cell specification. The techniques used to study cell fate in this species, and the themes that have emerged, are described...
  5. ncbi Maternal deployment of the embryonic SKN-1-->MED-1,2 cell specification pathway in C. elegans
    Morris F Maduro
    Department of Biology, 3380 Spieth Hall, University of California, Riverside, Riverside, CA 92521, USA
    Dev Biol 301:590-601. 2007
    ....
  6. ncbi The noncanonical binding site of the MED-1 GATA factor defines differentially regulated target genes in the C. elegans mesendoderm
    Gina Broitman-Maduro
    Department of Biology and Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California 93106, USA
    Dev Cell 8:427-33. 2005
    ..Some MED targets encode transcription factors related to those that regulate mesendoderm development in other phyla, supporting the existence of an ancient metazoan mesendoderm gene regulatory network...
  7. ncbi Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network
    Melissa Owraghi
    Department of Biology, University of California, 2121A Genomics Building, Riverside, Riverside, CA 92521, USA
    Dev Biol 340:209-21. 2010
    ..The findings reported here shed new light on the flexibility of combinatorial control mechanisms in endomesoderm specification in Caenorhabditis...
  8. ncbi Genetic redundancy in endoderm specification within the genus Caenorhabditis
    Morris F Maduro
    Department of Molecular, Cellular and Developmental Biology and Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA
    Dev Biol 284:509-22. 2005
    ..briggsae end genes also function redundantly to specify endoderm. We propose that duplicated end genes have been maintained over long periods of evolution, owing in part to their synergistic function...
  9. ncbi Med-type GATA factors and the evolution of mesendoderm specification in nematodes
    Cristian Coroian
    Department of Biology, UC Riverside, 3380 Spieth Hall, Riverside, CA 92521, USA
    Dev Biol 289:444-55. 2006
    ..elegans med-1,2(-) strain. We conclude that Med function and expression have been conserved over tens of millions of years of evolution, and that there may be a mechanism that selects against the acquisition of introns in these genes...
  10. ncbi Specification of the C. elegans MS blastomere by the T-box factor TBX-35
    Gina Broitman-Maduro
    Department of Biology, University of California, Riverside, Riverside, CA 92521, USA
    Development 133:3097-106. 2006
    ..Our results show that this role has been evolutionarily conserved in the early C. elegans embryo, and that a progenitor of multiple tissue types can be specified by a surprisingly simple gene cascade...
  11. ncbi Endoderm development in Caenorhabditis elegans: the synergistic action of ELT-2 and -7 mediates the specification?differentiation transition
    Erica M Sommermann
    Department of Molecular, Cellular, and Developmental Biology, and Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA
    Dev Biol 347:154-66. 2010
    ....
  12. ncbi Endomesoderm specification in Caenorhabditis elegans and other nematodes
    Morris F Maduro
    Department of Biology, University of California, Riverside, Riverside, CA 92521, USA
    Bioessays 28:1010-22. 2006
    ....
  13. ncbi Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein
    Kyunghee Koh
    Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA
    Development 129:5171-80. 2002
    ..These findings demonstrate that the EGL-18 and ELT-6 GATA factors are essential, genetically redundant regulators of cell fates and fusion in the developing vulva and are apparent direct transcriptional targets of the LIN-39 Hox protein...
  14. ncbi Dynamics of a developmental switch: recursive intracellular and intranuclear redistribution of Caenorhabditis elegans POP-1 parallels Wnt-inhibited transcriptional repression
    Morris F Maduro
    Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA
    Dev Biol 248:128-42. 2002
    ..Thus, a Tcf/Lef factor represses transactivation of genes in an unsignaled daughter cell by abrogating the function of a bound activator...
  15. ncbi In situ hybridization of embryos with antisense RNA probes
    Gina Broitman-Maduro
    Department of Biology, University of California at Riverside, Riverside, California, USA
    Methods Cell Biol 106:253-70. 2011
    ..Rather, we describe an alternative protocol that uses RNA probes with a different fixative. This approach has been applied to C. elegans and related nematodes, providing reliable, sensitive detection of endogenous transcripts...
  16. ncbi Making worm guts: the gene regulatory network of the Caenorhabditis elegans endoderm
    Morris F Maduro
    Department of MCD Biology and Neuroscience Research Institute, University of California, Santa Barbara 93106, USA
    Dev Biol 246:68-85. 2002
    ..elegans. Dissection of the architecture of the C. elegans endoderm network may provide insights into the evolutionary plasticity and origins of this germ layer...
  17. ncbi The Wnt effector POP-1 and the PAL-1/Caudal homeoprotein collaborate with SKN-1 to activate C. elegans endoderm development
    Morris F Maduro
    Department of MCD Biology and Neuroscience Research Institute, University of California at Santa Barbara, Santa Barbara, CA 93106, USA
    Dev Biol 285:510-23. 2005
    ....

Research Grants2

  1. Specification of embryonic C. elegans mesoderm by a T-box factor
    Morris Maduro; Fiscal Year: 2007
    ..elegans may shed light on how development goes awry, a process which can lead to birth defects or cancer. ..